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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

8533

Name

COPS3

Synonymous

COP9 signalosome subunit 3;COPS3;COP9 signalosome subunit 3

Definition

COP9 complex subunit 3|COP9 constitutive photomorphogenic homolog subunit 3|COP9 signalosome complex subunit 3|JAB1-containing signalosome subunit 3|signalosome subunit 3

Position

17p11.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.797T>C; p.V266A; 17:17260440-17260440

 breastcarcinomaSubstitution - Missense

c.387C>A; p.D129E; 17:17267939-17267939

 breastcarcinomaSubstitution - Missense

c.527A>G; p.Y176C; 17:17264896-17264896

 breastcarcinomaSubstitution - Missense

c.842A>G; p.K281R; 17:17260395-17260395

 breastcarcinomaSubstitution - Missense

c.883G>T; p.V295L; 17:17260354-17260354

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.677A>C; p.K226T; 17:17262051-17262051

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.480A>G; p.P160P; 17:17264943-17264943

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.281G>A; p.R94Q; 17:17270913-17270913

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.997G>A; p.E333K; 17:17254885-17254885

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.493G>A; p.D165N; 17:17264930-17264930

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.297T>G; p.T99T; 17:17270897-17270897

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.222C>T; p.F74F; 17:17270972-17270972

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1169T>C; p.L390P; 17:17247529-17247529

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.679T>C; p.Y227H; 17:17262049-17262049

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.170G>A; p.G57D; 17:17276050-17276050

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.42G>T; p.Q14H; 17:17281145-17281145

 kidneyother; neoplasmSubstitution - Missense

c.228G>A; p.T76T; 17:17270966-17270966

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.713T>C; p.V238A; 17:17262015-17262015

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.645G>A; p.A215A; 17:17262083-17262083

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.931A>G; p.T311A; 17:17260306-17260306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.490G>A; p.V164M; 17:17264933-17264933

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1165C>T; p.R389W; 17:17247533-17247533

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.378A>C; p.Q126H; 17:17267948-17267948

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.783C>T; p.H261H; 17:17260454-17260454

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.783C>T; p.H261H; 17:17260454-17260454

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1048A>G; p.S350G; 17:17249015-17249015

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.975T>G; p.R325R; 17:17254907-17254907

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.86A>G; p.N29S; 17:17276134-17276134

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.466A>G; p.K156E; 17:17264957-17264957

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.588G>T; p.K196N; 17:17264835-17264835

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.915_917delGAA; p.K305delK; 17:17260320-17260322

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.967G>A; p.A323T; 17:17254915-17254915

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.863G>A; p.R288H; 17:17260374-17260374

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1166G>A; p.R389Q; 17:17247532-17247532

 livercarcinomaSubstitution - Missense

c.1127T>C; p.I376T; 17:17248936-17248936

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.827G>T; p.R276L; 17:17260410-17260410

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.57G>A; p.G19G; 17:17276163-17276163

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.502G>C; p.D168H; 17:17264921-17264921

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1262G>T; p.S421I; 17:17247108-17247108

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.433C>G; p.L145V; 17:17267893-17267893

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.680A>T; p.Y227F; 17:17262048-17262048

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.244C>T; p.Q82*; 17:17270950-17270950

 lung; left_lower_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.299-2A>G; p.?; 17:17270809-17270809

 lung; right_upper_lobecarcinoma; adenocarcinomaUnknown

c.951A>G; p.L317L; 17:17254931-17254931

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.621G>T; p.Q207H; 17:17264802-17264802

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.157G>C; p.E53Q; 17:17276063-17276063

 NSNSSubstitution - Missense

c.1013T>C; p.V338A; 17:17254869-17254869

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.362T>A; p.I121N; 17:17267964-17267964

 ovarycarcinomaSubstitution - Missense

c.692C>T; p.S231F; 17:17262036-17262036

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1213C>A; p.Q405K; 17:17247485-17247485

 prostateadenomaSubstitution - Missense

c.56-2A>G; p.?; 17:17276166-17276166

 skinmalignant_melanomaUnknown

c.590A>T; p.N197I; 17:17264833-17264833

 skinmalignant_melanomaSubstitution - Missense

c.42G>A; p.Q14Q; 17:17281145-17281145

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.590A>C; p.N197T; 17:17264833-17264833

 skinmalignant_melanomaSubstitution - Missense

c.646G>A; p.V216I; 17:17262082-17262082

 skinmalignant_melanomaSubstitution - Missense

c.701T>A; p.L234*; 17:17262027-17262027

 skinmalignant_melanomaSubstitution - Nonsense

c.379G>A; p.A127T; 17:17267947-17267947

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - Missense

c.379G>A; p.A127T; 17:17267947-17267947

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.416C>G; p.T139S; 17:17267910-17267910

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.346C>G; p.Q116E; 17:17270760-17270760

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.107C>T; p.A36V; 17:17276113-17276113

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.448T>C; p.L150L; 17:17264975-17264975

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.56-3C>T; p.?; 17:17276167-17276167

 thyroidother; neoplasmUnknown

c.1170G>A; p.L390L; 17:17247528-17247528

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.777A>G; p.A259A; 17:17260460-17260460

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.777A>G; p.A259A; 17:17260460-17260460

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1170G>A; p.L390L; 17:17247528-17247528

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1170G>A; p.L390L; 17:17247528-17247528

 urinary_tract; bladdercarcinomaSubstitution - coding silent