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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

84951

Name

TNS4

Synonymous

tensin 4;TNS4;tensin 4

Definition

C terminal tensin like|C-terminal tensin-like protein|tensin-4

Position

17q21.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1651A>T; p.K551*; 17:40482150-40482150

 autonomic_ganglianeuroblastomaSubstitution - Nonsense

c.801G>T; p.R267R; 17:40488608-40488608

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.722C>T; p.S241L; 17:40488687-40488687

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.584G>A; p.R195Q; 17:40488825-40488825

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1942A>C; p.T648P; 17:40478617-40478617

 breastcarcinomaSubstitution - Missense

c.536T>C; p.L179P; 17:40488873-40488873

 breastcarcinomaSubstitution - Missense

c.1234A>C; p.T412P; 17:40487090-40487090

 breastcarcinomaSubstitution - Missense

c.1168C>A; p.R390R; 17:40487156-40487156

 breastcarcinomaSubstitution - coding silent

c.563G>A; p.R188K; 17:40488846-40488846

 breastcarcinomaSubstitution - Missense

c.1228C>T; p.P410S; 17:40487096-40487096

 breastcarcinomaSubstitution - Missense

c.1366C>T; p.R456*; 17:40484930-40484930

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Nonsense

c.658G>T; p.G220C; 17:40488751-40488751

 breastcarcinomaSubstitution - Missense

c.970T>G; p.S324A; 17:40487354-40487354

 breastcarcinomaSubstitution - Missense

c.1644G>T; p.L548L; 17:40482157-40482157

 breastcarcinomaSubstitution - coding silent

c.536T>C; p.L179P; 17:40488873-40488873

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1274C>A; p.T425N; 17:40487050-40487050

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1323C>T; p.F441F; 17:40484973-40484973

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.205G>A; p.A69T; 17:40496221-40496221

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1848G>A; p.T616T; 17:40479736-40479736

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.503C>G; p.S168C; 17:40488906-40488906

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.352C>A; p.L118M; 17:40496074-40496074

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2039A>C; p.E680A; 17:40477697-40477697

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.735T>C; p.G245G; 17:40488674-40488674

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1248C>A; p.S416R; 17:40487076-40487076

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1659C>T; p.T553T; 17:40482142-40482142

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.343A>G; p.T115A; 17:40496083-40496083

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1482G>A; p.A494A; 17:40484503-40484503

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1949G>A; p.R650H; 17:40478610-40478610

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1319A>C; p.K440T; 17:40484977-40484977

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1854C>T; p.T618T; 17:40479730-40479730

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.575G>A; p.R192Q; 17:40488834-40488834

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1493G>A; p.S498N; 17:40484492-40484492

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1640C>T; p.A547V; 17:40482161-40482161

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia_associated_with_MDSSubstitution - Missense

c.1908G>A; p.R636R; 17:40479676-40479676

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; polycythaemia_veraSubstitution - coding silent

c.211C>A; p.Q71K; 17:40496215-40496215

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.925A>T; p.S309C; 17:40487399-40487399

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1793C>A; p.A598D; 17:40479791-40479791

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1491G>T; p.Q497H; 17:40484494-40484494

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.522G>A; p.P174P; 17:40488887-40488887

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.271C>A; p.P91T; 17:40496155-40496155

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2135C>A; p.A712E; 17:40477601-40477601

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1924C>T; p.R642C; 17:40478635-40478635

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1924C>T; p.R642C; 17:40478635-40478635

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1406G>A; p.G469E; 17:40484579-40484579

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.470G>T; p.R157I; 17:40488939-40488939

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1087C>T; p.P363S; 17:40487237-40487237

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.771G>T; p.E257D; 17:40488638-40488638

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1156T>C; p.S386P; 17:40487168-40487168

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1042C>T; p.P348S; 17:40487282-40487282

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.169G>A; p.V57M; 17:40496257-40496257

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1337C>A; p.S446Y; 17:40484959-40484959

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.26T>C; p.L9P; 17:40496400-40496400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1493G>A; p.S498N; 17:40484492-40484492

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1366C>T; p.R456*; 17:40484930-40484930

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1790G>A; p.G597E; 17:40479794-40479794

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.243G>A; p.P81P; 17:40496183-40496183

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1676T>C; p.L559P; 17:40480765-40480765

 livercarcinomaSubstitution - Missense

c.1676T>C; p.L559P; 17:40480765-40480765

 livercarcinomaSubstitution - Missense

c.128A>G; p.Y43C; 17:40496298-40496298

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1741+1G>T; p.?; 17:40480699-40480699

 lungcarcinoma; adenocarcinomaUnknown

c.1294G>A; p.A432T; 17:40485002-40485002

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.758C>T; p.S253F; 17:40488651-40488651

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1977G>T; p.R659R; 17:40478582-40478582

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1544C>G; p.S515W; 17:40482374-40482374

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1828G>T; p.E610*; 17:40479756-40479756

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.680A>T; p.N227I; 17:40488729-40488729

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1285G>T; p.E429*; 17:40487039-40487039

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.361_362insT; p.P121fs*9; 17:40496064-40496065

 lungcarcinoma; adenocarcinomaInsertion - Frameshift

c.1205C>T; p.A402V; 17:40487119-40487119

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1843C>T; p.P615S; 17:40479741-40479741

 NSmalignant_melanomaSubstitution - Missense

c.567C>T; p.D189D; 17:40488842-40488842

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.409A>G; p.M137V; 17:40496017-40496017

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1234A>G; p.T412A; 17:40487090-40487090

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1556G>C; p.G519A; 17:40482362-40482362

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1110G>A; p.V370V; 17:40487214-40487214

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1554_1555insA; p.G519fs*9; 17:40482363-40482364

 ovarycarcinoma; serous_carcinomaInsertion - Frameshift

c.1790G>A; p.G597E; 17:40479794-40479794

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.722C>T; p.S241L; 17:40488687-40488687

 pancreascarcinomaSubstitution - Missense

c.2106C>T; p.I702I; 17:40477630-40477630

 pancreascarcinomaSubstitution - coding silent

c.191G>A; p.G64D; 17:40496235-40496235

 pancreascarcinomaSubstitution - Missense

c.191G>A; p.G64D; 17:40496235-40496235

 pancreascarcinomaSubstitution - Missense

c.191G>A; p.G64D; 17:40496235-40496235

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.327C>G; p.I109M; 17:40496099-40496099

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.327C>G; p.I109M; 17:40496099-40496099

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.1288+8G>A; p.?; 17:40487028-40487028

 pancreascarcinoid-endocrine_tumourUnknown

c.1847C>T; p.T616M; 17:40479737-40479737

 pancreascarcinomaSubstitution - Missense

c.1605T>A; p.S535S; 17:40482196-40482196

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.2086C>T; p.Q696*; 17:40477650-40477650

 prostatecarcinomaSubstitution - Nonsense

c.1553A>C; p.K518T; 17:40482365-40482365

 prostatecarcinomaSubstitution - Missense

c.1052C>T; p.P351L; 17:40487272-40487272

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.1626C>T; p.S542S; 17:40482175-40482175

 skinmalignant_melanomaSubstitution - coding silent

c.1381G>A; p.E461K; 17:40484604-40484604

 skin; trunkmalignant_melanomaSubstitution - Missense

c.957C>T; p.S319S; 17:40487367-40487367

 skinmalignant_melanomaSubstitution - coding silent

c.1169G>A; p.R390Q; 17:40487155-40487155

 skinmalignant_melanomaSubstitution - Missense

c.683C>T; p.S228F; 17:40488726-40488726

 skin; legmalignant_melanomaSubstitution - Missense

c.683C>T; p.S228F; 17:40488726-40488726

 skin; legmalignant_melanomaSubstitution - Missense

c.683C>T; p.S228F; 17:40488726-40488726

 skinmalignant_melanomaSubstitution - Missense

c.683C>T; p.S228F; 17:40488726-40488726

 skin; facemalignant_melanomaSubstitution - Missense

c.337G>A; p.D113N; 17:40496089-40496089

 skinmalignant_melanomaSubstitution - Missense

c.358C>T; p.P120S; 17:40496068-40496068

 skinmalignant_melanomaSubstitution - Missense

c.358C>T; p.P120S; 17:40496068-40496068

 skinmalignant_melanomaSubstitution - Missense

c.508C>T; p.P170S; 17:40488901-40488901

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.508C>T; p.P170S; 17:40488901-40488901

 skinmalignant_melanomaSubstitution - Missense

c.528C>T; p.F176F; 17:40488881-40488881

 skinmalignant_melanomaSubstitution - coding silent

c.645G>T; p.L215L; 17:40488764-40488764

 skinmalignant_melanomaSubstitution - coding silent

c.653C>T; p.S218L; 17:40488756-40488756

 skin; facemalignant_melanomaSubstitution - Missense

c.1253C>T; p.T418I; 17:40487071-40487071

 skinmalignant_melanomaSubstitution - Missense

c.1921C>T; p.R641W; 17:40478638-40478638

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.206C>T; p.A69V; 17:40496220-40496220

 skin; lower_legmalignant_melanomaSubstitution - Missense

c.655G>A; p.E219K; 17:40488754-40488754

 skinmalignant_melanomaSubstitution - Missense

c.667_668CC>TT; p.P223F; 17:40488741-40488742

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1386G>T; p.L462L; 17:40484599-40484599

 skinmalignant_melanomaSubstitution - coding silent

c.222C>T; p.A74A; 17:40496204-40496204

 skinmalignant_melanomaSubstitution - coding silent

c.1055C>T; p.P352L; 17:40487269-40487269

 skin; shouldermalignant_melanomaSubstitution - Missense

c.512C>T; p.S171F; 17:40488897-40488897

 skinmalignant_melanomaSubstitution - Missense

c.136G>A; p.E46K; 17:40496290-40496290

 skinmalignant_melanomaSubstitution - Missense

c.1438C>T; p.R480*; 17:40484547-40484547

 skinmalignant_melanomaSubstitution - Nonsense

c.453C>T; p.I151I; 17:40488956-40488956

 skinmalignant_melanomaSubstitution - coding silent

c.2122C>T; p.L708L; 17:40477614-40477614

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1291C>T; p.P431S; 17:40485005-40485005

 skinmalignant_melanomaSubstitution - Missense

c.1491G>A; p.Q497Q; 17:40484494-40484494

 skinmalignant_melanomaSubstitution - coding silent

c.2003C>T; p.S668F; 17:40478310-40478310

 skinmalignant_melanomaSubstitution - Missense

c.2141G>A; p.R714K; 17:40477595-40477595

 skinmalignant_melanomaSubstitution - Missense

c.1362C>T; p.I454I; 17:40484934-40484934

 skinmalignant_melanomaSubstitution - coding silent

c.1730A>C; p.K577T; 17:40480711-40480711

 skinmalignant_melanomaSubstitution - Missense

c.686C>T; p.P229L; 17:40488723-40488723

 skinmalignant_melanomaSubstitution - Missense

c.1987A>T; p.K663*; 17:40478326-40478326

 skinmalignant_melanomaSubstitution - Nonsense

c.666C>T; p.S222S; 17:40488743-40488743

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.524C>T; p.P175L; 17:40488885-40488885

 skinmalignant_melanomaSubstitution - Missense

c.1940C>T; p.T647I; 17:40478619-40478619

 skin; neckmalignant_melanomaSubstitution - Missense

c.1283C>T; p.P428L; 17:40487041-40487041

 skin; armmalignant_melanomaSubstitution - Missense

c.806G>A; p.S269N; 17:40488603-40488603

 skinmalignant_melanomaSubstitution - Missense

c.1430C>T; p.S477F; 17:40484555-40484555

 skinmalignant_melanomaSubstitution - Missense

c.477G>T; p.R159S; 17:40488932-40488932

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - Missense

c.477G>T; p.R159S; 17:40488932-40488932

 soft_tissue; striated_musclerhabdomyosarcoma; alveolarSubstitution - Missense

c.1914G>A; p.V638V; 17:40478645-40478645

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2074T>C; p.Y692H; 17:40477662-40477662

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1654C>T; p.L552F; 17:40482147-40482147

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.212_238del27; p.Q71_F79delQVEAKATCF; 17:40496188-40496214

 stomachcarcinoma; diffuse_adenocarcinomaDeletion - In frame

c.1855G>A; p.V619M; 17:40479729-40479729

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.574C>T; p.R192*; 17:40488835-40488835

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.169G>A; p.V57M; 17:40496257-40496257

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.915A>C; p.R305S; 17:40487409-40487409

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1975C>T; p.R659W; 17:40478584-40478584

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.907T>A; p.S303T; 17:40487417-40487417

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.445A>T; p.K149*; 17:40488964-40488964

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.242C>T; p.P81L; 17:40496184-40496184

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1367G>A; p.R456Q; 17:40484929-40484929

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.536T>C; p.L179P; 17:40488873-40488873

 thyroidother; neoplasmSubstitution - Missense

c.679A>C; p.N227H; 17:40488730-40488730

 thyroidother; neoplasmSubstitution - Missense

c.1493G>A; p.S498N; 17:40484492-40484492

 thyroidother; neoplasmSubstitution - Missense

c.1211C>T; p.S404F; 17:40487113-40487113

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.473C>T; p.S158L; 17:40488936-40488936

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.473C>T; p.S158L; 17:40488936-40488936

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.611C>G; p.S204C; 17:40488798-40488798

 urinary_tract; bladdercarcinomaSubstitution - Missense