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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

81607

Name

PVRL4

Synonymous

poliovirus receptor-related 4;PVRL4;poliovirus receptor-related 4

Definition

Ig superfamily receptor LNIR|nectin 4|nectin-4|poliovirus receptor-related protein 4

Position

1q23.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.112G>T; p.D38Y; 1:161079917-161079917

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.1018G>T; p.G340W; 1:161074356-161074356

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.1260C>T; p.A420A; 1:161073273-161073273

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1473C>T; p.T491T; 1:161072721-161072721

 breastcarcinomaSubstitution - coding silent

c.1261G>C; p.E421Q; 1:161073272-161073272

 breastcarcinomaSubstitution - Missense

c.840C>T; p.Y280Y; 1:161076366-161076366

 breastcarcinomaSubstitution - coding silent

c.71C>T; p.S24L; 1:161089226-161089226

 breastcarcinomaSubstitution - Missense

c.290G>A; p.R97H; 1:161079739-161079739

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.290G>A; p.R97H; 1:161079739-161079739

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.91G>A; p.A31T; 1:161079938-161079938

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.91G>A; p.A31T; 1:161079938-161079938

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1249G>A; p.G417R; 1:161073284-161073284

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1249G>A; p.G417R; 1:161073284-161073284

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.640C>T; p.R214C; 1:161077543-161077543

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.1072G>A; p.A358T; 1:161074302-161074302

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1072G>A; p.A358T; 1:161074302-161074302

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1072G>A; p.A358T; 1:161074302-161074302

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1173C>A; p.T391T; 1:161073780-161073780

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.327C>T; p.D109D; 1:161079702-161079702

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.665C>T; p.T222I; 1:161077518-161077518

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1036G>A; p.V346M; 1:161074338-161074338

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeSubstitution - Missense

c.57_59delGCT; p.L22delL; 1:161089238-161089240

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - In frame

c.57_59delGCT; p.L22delL; 1:161089238-161089240

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - In frame

c.57_59delGCT; p.L22delL; 1:161089238-161089240

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - In frame

c.83G>A; p.R28Q; 1:161079946-161079946

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1126C>A; p.R376R; 1:161074248-161074248

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.711C>A; p.T237T; 1:161077472-161077472

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1061G>A; p.G354D; 1:161074313-161074313

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1233G>T; p.Q411H; 1:161073720-161073720

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1516C>T; p.R506W; 1:161072678-161072678

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.259G>A; p.G87R; 1:161079770-161079770

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.57_59delGCT; p.L22delL; 1:161089238-161089240

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - In frame

c.57_59delGCT; p.L22delL; 1:161089238-161089240

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.762A>C; p.E254D; 1:161076444-161076444

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.431G>A; p.R144Q; 1:161079598-161079598

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1434C>A; p.I478I; 1:161072760-161072760

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.608C>T; p.A203V; 1:161077575-161077575

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1117C>T; p.R373*; 1:161074257-161074257

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1053G>T; p.V351V; 1:161074321-161074321

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.71C>T; p.S24L; 1:161089226-161089226

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.599G>A; p.R200H; 1:161077584-161077584

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.344G>A; p.R115H; 1:161079685-161079685

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.291C>T; p.R97R; 1:161079738-161079738

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1433T>C; p.I478T; 1:161072761-161072761

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1433T>C; p.I478T; 1:161072761-161072761

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1433T>C; p.I478T; 1:161072761-161072761

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.554C>T; p.T185M; 1:161077629-161077629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.220G>A; p.E74K; 1:161079809-161079809

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.551A>G; p.D184G; 1:161077632-161077632

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1009G>A; p.E337K; 1:161074365-161074365

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1105_1107delGTG; p.V369delV; 1:161074267-161074269

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.1105_1107delGTG; p.V369delV; 1:161074267-161074269

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1105_1107delGTG; p.V369delV; 1:161074267-161074269

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.887A>G; p.D296G; 1:161074724-161074724

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.68C>T; p.A23V; 1:161089229-161089229

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.639C>T; p.S213S; 1:161077544-161077544

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.418C>T; p.R140W; 1:161079611-161079611

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.242T>G; p.L81R; 1:161079787-161079787

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1171A>G; p.T391A; 1:161073782-161073782

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.214G>T; p.A72S; 1:161079815-161079815

 livercarcinomaSubstitution - Missense

c.214G>T; p.A72S; 1:161079815-161079815

 livercarcinomaSubstitution - Missense

c.302C>T; p.P101L; 1:161079727-161079727

 livercarcinomaSubstitution - Missense

c.302C>T; p.P101L; 1:161079727-161079727

 livercarcinomaSubstitution - Missense

c.1485G>T; p.K495N; 1:161072709-161072709

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1288A>T; p.N430Y; 1:161073245-161073245

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1183G>A; p.E395K; 1:161073770-161073770

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.299A>T; p.Q100L; 1:161079730-161079730

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1375G>A; p.E459K; 1:161072819-161072819

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1146G>T; p.M382I; 1:161074228-161074228

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.348C>T; p.N116N; 1:161079681-161079681

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1218G>A; p.T406T; 1:161073735-161073735

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1013A>T; p.D338V; 1:161074361-161074361

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.509C>G; p.S170C; 1:161077674-161077674

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.92C>T; p.A31V; 1:161079937-161079937

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.792A>C; p.E264D; 1:161076414-161076414

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.990G>T; p.V330V; 1:161074621-161074621

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1016C>G; p.S339C; 1:161074358-161074358

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1261G>A; p.E421K; 1:161073272-161073272

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.491G>A; p.G164D; 1:161077692-161077692

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.649A>G; p.N217D; 1:161077534-161077534

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.552C>A; p.D184E; 1:161077631-161077631

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1432A>G; p.I478V; 1:161072762-161072762

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.431G>T; p.R144L; 1:161079598-161079598

 ovaryother; neoplasmSubstitution - Missense

c.1265G>A; p.G422D; 1:161073268-161073268

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.1473C>T; p.T491T; 1:161072721-161072721

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1170G>A; p.L390L; 1:161073783-161073783

 skinmalignant_melanomaSubstitution - coding silent

c.259G>A; p.G87R; 1:161079770-161079770

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.892G>A; p.D298N; 1:161074719-161074719

 skinmalignant_melanomaSubstitution - Missense

c.936C>T; p.I312I; 1:161074675-161074675

 skinmalignant_melanomaSubstitution - coding silent

c.429C>T; p.L143L; 1:161079600-161079600

 skinmalignant_melanomaSubstitution - coding silent

c.772C>T; p.L258L; 1:161076434-161076434

 skinmalignant_melanomaSubstitution - coding silent

c.431G>A; p.R144Q; 1:161079598-161079598

 skinmalignant_melanomaSubstitution - Missense

c.1420C>T; p.Q474*; 1:161072774-161072774

 skinmalignant_melanomaSubstitution - Nonsense

c.474A>C; p.A158A; 1:161077709-161077709

 skinmalignant_melanomaSubstitution - coding silent

c.1423G>A; p.D475N; 1:161072771-161072771

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.977C>T; p.S326F; 1:161074634-161074634

 skinmalignant_melanomaSubstitution - Missense

c.397C>T; p.P133S; 1:161079632-161079632

 skinmalignant_melanomaSubstitution - Missense

c.328G>A; p.G110S; 1:161079701-161079701

 skinmalignant_melanomaSubstitution - Missense

c.555G>A; p.T185T; 1:161077628-161077628

 skinmalignant_melanomaSubstitution - coding silent

c.922G>A; p.E308K; 1:161074689-161074689

 skinmalignant_melanomaSubstitution - Missense

c.885G>A; p.V295V; 1:161074726-161074726

 skinmalignant_melanomaSubstitution - coding silent

c.222A>G; p.E74E; 1:161079807-161079807

 skinmalignant_melanomaSubstitution - coding silent

c.1020G>A; p.G340G; 1:161074354-161074354

 skinmalignant_melanomaSubstitution - coding silent

c.1020G>A; p.G340G; 1:161074354-161074354

 skinmalignant_melanomaSubstitution - coding silent

c.832C>T; p.P278S; 1:161076374-161076374

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.570A>C; p.T190T; 1:161077613-161077613

 skinmalignant_melanomaSubstitution - coding silent

c.1462G>A; p.E488K; 1:161072732-161072732

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1090C>T; p.L364L; 1:161074284-161074284

 skinmalignant_melanomaSubstitution - coding silent

c.11C>T; p.S4F; 1:161089286-161089286

 skinmalignant_melanomaSubstitution - Missense

c.89C>T; p.P30L; 1:161079940-161079940

 skinmalignant_melanomaSubstitution - Missense

c.89C>T; p.P30L; 1:161079940-161079940

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1009G>A; p.E337K; 1:161074365-161074365

 skinmalignant_melanomaSubstitution - Missense

c.556G>A; p.E186K; 1:161077627-161077627

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1191C>T; p.S397S; 1:161073762-161073762

 skinmalignant_melanomaSubstitution - coding silent

c.708C>T; p.I236I; 1:161077475-161077475

 skinmalignant_melanomaSubstitution - coding silent

c.1235C>T; p.P412L; 1:161073298-161073298

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.530C>T; p.P177L; 1:161077653-161077653

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.259G>A; p.G87R; 1:161079770-161079770

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.930C>T; p.S310S; 1:161074681-161074681

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.850C>T; p.R284W; 1:161076356-161076356

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.231G>T; p.Q77H; 1:161079798-161079798

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1068C>T; p.I356I; 1:161074306-161074306

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1218G>A; p.T406T; 1:161073735-161073735

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.176G>A; p.G59D; 1:161079853-161079853

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.939C>T; p.Y313Y; 1:161074672-161074672

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.258C>T; p.Y86Y; 1:161079771-161079771

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1328G>A; p.R443H; 1:161072866-161072866

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.268G>A; p.V90M; 1:161079761-161079761

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.540C>T; p.S180S; 1:161077643-161077643

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.540C>T; p.S180S; 1:161077643-161077643

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.804C>G; p.L268L; 1:161076402-161076402

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1077C>G; p.L359L; 1:161074297-161074297

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.788G>C; p.R263T; 1:161076418-161076418

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.617C>T; p.S206L; 1:161077566-161077566

 urinary_tract; bladdercarcinomaSubstitution - Missense