Entrez Gene

Basic Information
Gene ID	79923
Name	NANOG
Synonymous	Nanog homeobox;NANOG;Nanog homeobox
Definition	homeobox protein NANOG\|homeobox transcription factor Nanog\|homeobox transcription factor Nanog-delta 48
Position	12p13.31
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.273C>T; p.V91V; 12:7793071-7793071	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.174G>A; p.M58I; 12:7792972-7792972	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.278T>C; p.V93A; 12:7793076-7793076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.203C>A; p.S68Y; 12:7793001-7793001	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.444G>T; p.M148I; 12:7794486-7794486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.14delC; p.P5fs*23; 12:7789628-7789628	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Deletion - Frameshift
c.45A>C; p.E15D; 12:7789659-7789659	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.525C>T; p.P175P; 12:7794702-7794702	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.327A>G; p.V109V; 12:7793125-7793125	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.731G>C; p.G244A; 12:7794908-7794908	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.97G>T; p.E33*; 12:7789711-7789711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.97G>T; p.E33*; 12:7789711-7789711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.460C>A; p.Q154K; 12:7794502-7794502	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.205T>C; p.S69P; 12:7793003-7793003	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.194G>A; p.S65N; 12:7792992-7792992	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.270G>T; p.K90N; 12:7793068-7793068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.52G>A; p.D18N; 12:7789666-7789666	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.25_26insA; p.S10fs*6; 12:7789639-7789640	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.467A>C; p.N156T; 12:7794509-7794509	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.49T>C; p.S17P; 12:7789663-7789663	liver	carcinoma	Substitution - Missense
c.49T>C; p.S17P; 12:7789663-7789663	liver	carcinoma	Substitution - Missense
c.208A>C; p.T70P; 12:7793006-7793006	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.798C>T; p.A266A; 12:7794975-7794975	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.183T>A; p.L61L; 12:7792981-7792981	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.88G>A; p.G30R; 12:7789702-7789702	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.195delC; p.P66fs*67; 12:7792993-7792993	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.149C>A; p.T50N; 12:7789763-7789763	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.31T>A; p.L11M; 12:7789645-7789645	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.70C>A; p.P24T; 12:7789684-7789684	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.115C>T; p.Q39*; 12:7789729-7789729	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.216C>A; p.P72P; 12:7793014-7793014	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.328C>A; p.L110I; 12:7793126-7793126	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.402C>T; p.L134L; 12:7793200-7793200	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.151G>T; p.V51F; 12:7789765-7789765	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.59A>G; p.K20R; 12:7789673-7789673	pancreas	carcinoma; adenocarcinoma	Substitution - Missense
c.137C>A; p.P46H; 12:7789751-7789751	pancreas	carcinoma	Substitution - Missense
c.51C>T; p.S17S; 12:7789665-7789665	prostate	adenoma	Substitution - coding silent
c.347G>T; p.R116I; 12:7793145-7793145	prostate	carcinoma	Substitution - Missense
c.158C>T; p.P53L; 12:7792956-7792956	skin	malignant_melanoma	Substitution - Missense
c.580C>T; p.P194S; 12:7794757-7794757	skin	malignant_melanoma	Substitution - Missense
c.400C>T; p.L134F; 12:7793198-7793198	skin	malignant_melanoma	Substitution - Missense
c.61G>A; p.E21K; 12:7789675-7789675	skin	malignant_melanoma	Substitution - Missense
c.775C>T; p.P259S; 12:7794952-7794952	skin; extremity	malignant_melanoma	Substitution - Missense
c.566C>T; p.P189L; 12:7794743-7794743	skin	malignant_melanoma	Substitution - Missense
c.106C>T; p.P36S; 12:7789720-7789720	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.444G>A; p.M148I; 12:7794486-7794486	skin	malignant_melanoma	Substitution - Missense
c.168C>T; p.S56S; 12:7792966-7792966	skin	malignant_melanoma	Substitution - coding silent
c.163C>T; p.P55S; 12:7792961-7792961	skin	malignant_melanoma	Substitution - Missense
c.163C>T; p.P55S; 12:7792961-7792961	skin	malignant_melanoma	Substitution - Missense
c.314C>T; p.T105I; 12:7793112-7793112	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.282G>A; p.K94K; 12:7793080-7793080	skin	malignant_melanoma	Substitution - coding silent
c.152-1G>T; p.?; 12:7792949-7792949	stomach	carcinoma; adenocarcinoma	Unknown
c.210C>G; p.T70T; 12:7793008-7793008	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.531T>C; p.L177L; 12:7794708-7794708	thyroid	other; neoplasm	Substitution - coding silent
c.798C>T; p.A266A; 12:7794975-7794975	thyroid	other; neoplasm	Substitution - coding silent
c.476C>T; p.P159L; 12:7794518-7794518	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.798C>T; p.A266A; 12:7794975-7794975	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.276G>A; p.P92P; 12:7793074-7793074	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246G>T; p.K82N; 12:7793044-7793044	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.54C>G; p.D18E; 12:7789668-7789668	urinary_tract; bladder	carcinoma	Substitution - Missense
c.365T>A; p.L122H; 12:7793163-7793163	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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