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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7525

Name

YES1

Synonymous

YES proto-oncogene 1, Src family tyrosine kinase;YES1;YES proto-oncogene 1, Src family tyrosine kinase

Definition

YES1 proto-oncogene, Src family tyrosine kinase|Yamaguchi sarcoma oncogene|cellular yes-1 protein|proto-oncogene c-Yes|proto-oncogene tyrosine-protein kinase YES|tyrosine-protein kinase Yes|v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1

Position

18p11.31-p11.21

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.107C>T; p.P36L; 18:756721-756721

 bone; tibiaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.137C>T; p.S46L; 18:756691-756691

 breastcarcinomaSubstitution - Missense

c.760G>C; p.V254L; 18:743380-743380

 breastcarcinomaSubstitution - Missense

c.118T>C; p.S40P; 18:756710-756710

 central_nervous_system; braingliomaSubstitution - Missense

c.350G>T; p.R117I; 18:751726-751726

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1378A>C; p.I460L; 18:732879-732879

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1406delG; p.G469fs*9; 18:732851-732851

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.559_560delAG; p.S187fs*1; 18:745962-745963

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.403G>A; p.A135T; 18:747987-747987

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.206C>T; p.T69M; 18:756622-756622

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1116G>A; p.Q372Q; 18:739756-739756

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1184G>A; p.R395Q; 18:736915-736915

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.978A>C; p.K326N; 18:743000-743000

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.64C>A; p.P22T; 18:756764-756764

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.627G>T; p.V209V; 18:745805-745805

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.502G>T; p.A168S; 18:746020-746020

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.592A>G; p.I198V; 18:745840-745840

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1351A>G; p.I451V; 18:732906-732906

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.134C>T; p.S45F; 18:756694-756694

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.1490G>C; p.C497S; 18:724566-724566

 kidneyother; neoplasmSubstitution - Missense

c.815T>G; p.I272S; 18:743325-743325

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.371+4A>C; p.?; 18:751701-751701

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.472T>C; p.W158R; 18:746050-746050

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1027C>T; p.P343S; 18:742951-742951

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.644G>T; p.R215M; 18:745788-745788

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.24A>C; p.E8D; 18:756804-756804

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.473G>A; p.W158*; 18:746049-746049

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1621G>T; p.E541*; 18:724435-724435

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1516A>G; p.N506D; 18:724540-724540

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.681A>T; p.R227S; 18:745751-745751

 large_intestine; colonadenomaSubstitution - Missense

c.276T>C; p.G92G; 18:751800-751800

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.474G>A; p.W158*; 18:746048-746048

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.403G>A; p.A135T; 18:747987-747987

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1485G>T; p.Q495H; 18:724571-724571

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.428C>T; p.P143L; 18:747962-747962

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1485G>T; p.Q495H; 18:724571-724571

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1475C>T; p.P492L; 18:724581-724581

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.868G>A; p.E290K; 18:743272-743272

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1488C>A; p.G496G; 18:724568-724568

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.98G>C; p.G33A; 18:756730-756730

 livercarcinomaSubstitution - Missense

c.98G>C; p.G33A; 18:756730-756730

 livercarcinomaSubstitution - Missense

c.1007A>G; p.Y336C; 18:742971-742971

 livercarcinomaSubstitution - Missense

c.1007A>G; p.Y336C; 18:742971-742971

 livercarcinomaSubstitution - Missense

c.1133C>G; p.A378G; 18:739739-739739

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1332A>G; p.A444A; 18:732925-732925

 livercarcinomaSubstitution - coding silent

c.1332A>G; p.A444A; 18:732925-732925

 livercarcinomaSubstitution - coding silent

c.1246G>A; p.G416S; 18:736853-736853

 livercarcinomaSubstitution - Missense

c.1246G>A; p.G416S; 18:736853-736853

 livercarcinomaSubstitution - Missense

c.1516A>T; p.N506Y; 18:724540-724540

 livercarcinomaSubstitution - Missense

c.1516A>T; p.N506Y; 18:724540-724540

 livercarcinomaSubstitution - Missense

c.313A>G; p.R105G; 18:751763-751763

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.787C>T; p.Q263*; 18:743353-743353

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1534G>T; p.D512Y; 18:724522-724522

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.835C>T; p.L279L; 18:743305-743305

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.253T>A; p.Y85N; 18:756575-756575

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.473G>T; p.W158L; 18:746049-746049

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.484A>T; p.K162*; 18:746038-746038

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.371+1G>T; p.?; 18:751704-751704

 lungcarcinoma; adenocarcinomaUnknown

c.372G>T; p.T124T; 18:748018-748018

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1113A>T; p.P371P; 18:739759-739759

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1521G>T; p.L507L; 18:724535-724535

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1558G>A; p.E520K; 18:724498-724498

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.87G>T; p.V29V; 18:756741-756741

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.427C>T; p.P143S; 18:747963-747963

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.825A>T; p.E275D; 18:743315-743315

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.614G>A; p.R205K; 18:745818-745818

 ovaryother; neoplasmSubstitution - Missense

c.1483C>T; p.Q495*; 18:724573-724573

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.685C>T; p.Q229*; 18:745747-745747

 pancreascarcinomaSubstitution - Nonsense

c.1243T>C; p.F415L; 18:736856-736856

 pituitary; craniopharyngeal_ductcraniopharyngioma; adamantinomatousSubstitution - Missense

c.711G>A; p.V237V; 18:745721-745721

 prostatecarcinomaSubstitution - coding silent

c.170T>C; p.L57P; 18:756658-756658

 skinmalignant_melanomaSubstitution - Missense

c.122C>T; p.P41L; 18:756706-756706

 skinmalignant_melanomaSubstitution - Missense

c.332C>T; p.S111L; 18:751744-751744

 skinmalignant_melanomaSubstitution - Missense

c.1149T>C; p.G383G; 18:736950-736950

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1282G>A; p.A428T; 18:736817-736817

 skinmalignant_melanomaSubstitution - Missense

c.1499C>T; p.S500F; 18:724557-724557

 skin; trunkmalignant_melanomaSubstitution - Missense

c.1499C>T; p.S500F; 18:724557-724557

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.951C>T; p.F317F; 18:743027-743027

 skinmalignant_melanomaSubstitution - coding silent

c.427C>T; p.P143S; 18:747963-747963

 skinmalignant_melanomaSubstitution - Missense

c.1272T>C; p.N424N; 18:736827-736827

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1315A>G; p.T439A; 18:732942-732942

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1408C>A; p.R470R; 18:732849-732849

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.669T>A; p.Y223*; 18:745763-745763

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.435T>C; p.N145N; 18:747955-747955

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.832C>T; p.R278*; 18:743308-743308

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - Nonsense

c.388G>A; p.E130K; 18:748002-748002

 thyroidcarcinomaSubstitution - Missense

c.1582G>A; p.D528N; 18:724474-724474

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1466A>G; p.Y489C; 18:724590-724590

 urinary_tract; bladdercarcinomaSubstitution - Missense