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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7472

Name

WNT2

Synonymous

wingless-type MMTV integration site family member 2;WNT2;wingless-type MMTV integration site family member 2

Definition

Int-1-related protein|int-1-like protein 1|protein Wnt-2|secreted growth factor

Position

7q31.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.433G>A; p.A145T; 7:117315226-117315226

 breastcarcinomaSubstitution - Missense

c.882_905del24; p.N295_D302del; 7:117278333-117278356

 breastcarcinoma; ductal_carcinomaDeletion - In frame

c.465T>C; p.G155G; 7:117315194-117315194

 breastcarcinomaSubstitution - coding silent

c.321A>G; p.E107E; 7:117315338-117315338

 breastcarcinoma; ER-PR-positive_carcinomaSubstitution - coding silent

c.1074C>T; p.T358T; 7:117278164-117278164

 breastcarcinomaSubstitution - coding silent

c.155G>A; p.R52Q; 7:117320722-117320722

 central_nervous_system; braingliomaSubstitution - Missense

c.692G>A; p.G231D; 7:117297773-117297773

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.187C>T; p.R63C; 7:117320690-117320690

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.958C>T; p.R320W; 7:117278280-117278280

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.307C>T; p.R103*; 7:117320570-117320570

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Nonsense

c.693C>T; p.G231G; 7:117297772-117297772

 central_nervous_system; braingliomaSubstitution - coding silent

c.326C>A; p.A109D; 7:117315333-117315333

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.251G>A; p.R84H; 7:117320626-117320626

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.317G>T; p.R106L; 7:117315342-117315342

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.205G>A; p.V69M; 7:117320672-117320672

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.308G>A; p.R103Q; 7:117320569-117320569

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.511T>C; p.F171L; 7:117315148-117315148

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1056G>T; p.K352N; 7:117278182-117278182

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.771C>T; p.N257N; 7:117297694-117297694

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.155G>A; p.R52Q; 7:117320722-117320722

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.667G>A; p.A223T; 7:117297798-117297798

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; polycythaemia_veraSubstitution - Missense

c.676G>A; p.D226N; 7:117297789-117297789

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.676G>A; p.D226N; 7:117297789-117297789

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.959G>A; p.R320Q; 7:117278279-117278279

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.338C>T; p.A113V; 7:117315321-117315321

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.996C>G; p.C332W; 7:117278242-117278242

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.575G>T; p.R192I; 7:117315084-117315084

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.68T>C; p.V23A; 7:117322922-117322922

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.558G>T; p.M186I; 7:117315101-117315101

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.489T>C; p.Y163Y; 7:117315170-117315170

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1013A>G; p.D338G; 7:117278225-117278225

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1000G>A; p.V334M; 7:117278238-117278238

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.997G>A; p.A333T; 7:117278241-117278241

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.997G>A; p.A333T; 7:117278241-117278241

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.508G>A; p.A170T; 7:117315151-117315151

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.816G>T; p.E272D; 7:117297649-117297649

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.261C>G; p.C87W; 7:117320616-117320616

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.263A>G; p.N88S; 7:117320614-117320614

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.263A>G; p.N88S; 7:117320614-117320614

 large_intestine; coloncarcinomaSubstitution - Missense

c.1059C>T; p.N353N; 7:117278179-117278179

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.637G>A; p.G213S; 7:117297828-117297828

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.227G>A; p.C76Y; 7:117320650-117320650

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.169C>T; p.R57*; 7:117320708-117320708

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.694G>A; p.D232N; 7:117297771-117297771

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1074C>T; p.T358T; 7:117278164-117278164

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.203G>A; p.G68D; 7:117320674-117320674

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.16G>A; p.G6S; 7:117322974-117322974

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.996C>T; p.C332C; 7:117278242-117278242

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.628G>A; p.G210R; 7:117297837-117297837

 livercarcinomaSubstitution - Missense

c.628G>A; p.G210R; 7:117297837-117297837

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.52T>A; p.W18R; 7:117322938-117322938

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.9C>T; p.A3A; 7:117322981-117322981

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.844C>A; p.R282R; 7:117297621-117297621

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.441C>T; p.D147D; 7:117315218-117315218

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.663G>C; p.W221C; 7:117297802-117297802

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.896G>T; p.R299L; 7:117278342-117278342

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.374G>T; p.R125M; 7:117315285-117315285

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.552C>A; p.A184A; 7:117315107-117315107

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.506G>A; p.R169H; 7:117315153-117315153

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.503C>T; p.A168V; 7:117315156-117315156

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.90G>A; p.M30I; 7:117320787-117320787

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.192C>T; p.A64A; 7:117320685-117320685

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.859C>A; p.L287M; 7:117278379-117278379

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.805G>T; p.V269L; 7:117297660-117297660

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.101G>C; p.G34A; 7:117320776-117320776

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.292G>C; p.G98R; 7:117320585-117320585

 NSmalignant_melanomaSubstitution - Missense

c.448G>A; p.G150S; 7:117315211-117315211

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.432C>T; p.S144S; 7:117315227-117315227

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.188G>A; p.R63H; 7:117320689-117320689

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.467G>A; p.G156D; 7:117315192-117315192

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.768T>A; p.A256A; 7:117297697-117297697

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.211G>A; p.E71K; 7:117320666-117320666

 ovaryother; neoplasmSubstitution - Missense

c.507C>T; p.R169R; 7:117315152-117315152

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.203G>A; p.G68D; 7:117320674-117320674

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.725T>A; p.I242N; 7:117297740-117297740

 pancreascarcinomaSubstitution - Missense

c.505C>A; p.R169S; 7:117315154-117315154

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.741C>G; p.N247K; 7:117297724-117297724

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.821C>T; p.S274F; 7:117297644-117297644

 skinmalignant_melanomaSubstitution - Missense

c.891T>G; p.T297T; 7:117278347-117278347

 skinmalignant_melanomaSubstitution - coding silent

c.215G>A; p.W72*; 7:117320662-117320662

 skinmalignant_melanomaSubstitution - Nonsense

c.505C>T; p.R169C; 7:117315154-117315154

 skin; neckmalignant_melanomaSubstitution - Missense

c.837C>T; p.I279I; 7:117297628-117297628

 skinmalignant_melanomaSubstitution - coding silent

c.550G>A; p.A184T; 7:117315109-117315109

 skinmalignant_melanomaSubstitution - Missense

c.492G>A; p.G164G; 7:117315167-117315167

 skinmalignant_melanomaSubstitution - coding silent

c.389G>A; p.G130E; 7:117315270-117315270

 skinmalignant_melanomaSubstitution - Missense

c.389G>A; p.G130E; 7:117315270-117315270

 skinmalignant_melanomaSubstitution - Missense

c.412G>A; p.D138N; 7:117315247-117315247

 skinmalignant_melanomaSubstitution - Missense

c.531G>A; p.R177R; 7:117315128-117315128

 skinmalignant_melanomaSubstitution - coding silent

c.849G>A; p.E283E; 7:117297616-117297616

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.799G>A; p.D267N; 7:117297666-117297666

 skinmalignant_melanomaSubstitution - Missense

c.799G>A; p.D267N; 7:117297666-117297666

 skinmalignant_melanomaSubstitution - Missense

c.799G>A; p.D267N; 7:117297666-117297666

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.420G>A; p.K140K; 7:117315239-117315239

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.372C>T; p.T124T; 7:117315287-117315287

 skinmalignant_melanomaSubstitution - coding silent

c.124G>A; p.D42N; 7:117320753-117320753

 skinmalignant_melanomaSubstitution - Missense

c.439G>A; p.D147N; 7:117315220-117315220

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.744G>A; p.Q248Q; 7:117297721-117297721

 skinmalignant_melanomaSubstitution - coding silent

c.291T>A; p.F97L; 7:117320586-117320586

 skinmalignant_melanomaSubstitution - Missense

c.1021G>A; p.E341K; 7:117278217-117278217

 skinmalignant_melanomaSubstitution - Missense

c.495C>T; p.I165I; 7:117315164-117315164

 skinmalignant_melanomaSubstitution - coding silent

c.255G>A; p.W85*; 7:117320622-117320622

 skinmalignant_melanomaSubstitution - Nonsense

c.156G>A; p.R52R; 7:117320721-117320721

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.199C>A; p.Q67K; 7:117320678-117320678

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.432C>T; p.S144S; 7:117315227-117315227

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.140_310+41del212; p.?; 7:117320526-117320737

 stomachcarcinoma; intestinal_adenocarcinomaUnknown

c.640T>A; p.S214T; 7:117297825-117297825

 stomachcarcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableSubstitution - Missense

c.477T>A; p.D159E; 7:117315182-117315182

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.308G>A; p.R103Q; 7:117320569-117320569

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.516G>T; p.V172V; 7:117315143-117315143

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1049C>T; p.A350V; 7:117278189-117278189

 stomachadenocarcinomaSubstitution - Missense

c.573C>A; p.N191K; 7:117315086-117315086

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.187C>T; p.R63C; 7:117320690-117320690

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.55C>T; p.L19F; 7:117322935-117322935

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.590C>T; p.A197V; 7:117297875-117297875

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.590C>T; p.A197V; 7:117297875-117297875

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.347C>T; p.S116L; 7:117315312-117315312

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.347C>T; p.S116L; 7:117315312-117315312

 urinary_tract; bladdercarcinomaSubstitution - Missense