ONGene
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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7298

Name

TYMS

Synonymous

thymidylate synthetase;TYMS;thymidylate synthetase

Definition

TSase|thymidylate synthase

Position

18p11.32

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.913C>T; p.P305S; 18:672968-672968

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.604T>C; p.Y202H; 18:670739-670739

 breastcarcinomaSubstitution - Missense

c.811C>T; p.R271*; 18:672866-672866

 endometriumcarcinoma; serous_carcinomaSubstitution - Nonsense

c.681C>T; p.I227I; 18:670816-670816

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.381A>G; p.E127E; 18:662247-662247

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.376A>G; p.R126G; 18:662242-662242

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.97T>C; p.Y33H; 18:657839-657839

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.700A>G; p.T234A; 18:670835-670835

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.646T>C; p.S216P; 18:670781-670781

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.519C>T; p.D173D; 18:669136-669136

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.691G>A; p.A231T; 18:670826-670826

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.430G>A; p.A144T; 18:662296-662296

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.902A>G; p.Y301C; 18:672957-672957

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.343C>T; p.R115*; 18:662209-662209

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.425T>G; p.F142C; 18:662291-662291

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.425T>G; p.F142C; 18:662291-662291

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.847C>T; p.R283*; 18:672902-672902

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.197G>A; p.S66N; 18:657939-657939

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.603C>A; p.F201L; 18:670738-670738

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.603C>A; p.F201L; 18:670738-670738

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.527G>A; p.R176K; 18:669144-669144

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.687C>G; p.S229R; 18:670822-670822

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.909G>A; p.P303P; 18:672964-672964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.634C>T; p.L212L; 18:670769-670769

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.636G>A; p.L212L; 18:670771-670771

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.606T>C; p.Y202Y; 18:670741-670741

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.494T>C; p.I165T; 18:669111-669111

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.572C>T; p.A191V; 18:670707-670707

 livercarcinomaSubstitution - Missense

c.572C>T; p.A191V; 18:670707-670707

 livercarcinomaSubstitution - Missense

c.572C>T; p.A191V; 18:670707-670707

 livercarcinomaSubstitution - Missense

c.445A>G; p.M149V; 18:662311-662311

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.663C>T; p.L221L; 18:670798-670798

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.594C>G; p.L198L; 18:670729-670729

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.889C>G; p.Q297E; 18:672944-672944

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.125G>T; p.R42L; 18:657867-657867

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.389A>G; p.D130G; 18:662255-662255

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.812G>A; p.R271Q; 18:672867-672867

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.590C>A; p.A197D; 18:670725-670725

 ovaryother; neoplasmSubstitution - Missense

c.590C>A; p.A197D; 18:670725-670725

 ovaryother; neoplasmSubstitution - Missense

c.590C>A; p.A197D; 18:670725-670725

 ovaryother; neoplasmSubstitution - Missense

c.703T>C; p.Y235H; 18:670838-670838

 pancreascarcinomaSubstitution - Missense

c.509C>T; p.T170I; 18:669126-669126

 skinmalignant_melanomaSubstitution - Missense

c.259G>A; p.E87K; 18:659694-659694

 skinmalignant_melanomaSubstitution - Missense

c.657G>A; p.M219I; 18:670792-670792

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.692_693CC>AT; p.A231D; 18:670827-670828

 skinmalignant_melanomaSubstitution - Missense

c.427G>A; p.G143R; 18:662293-662293

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - Missense

c.427G>A; p.G143R; 18:662293-662293

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.427G>A; p.G143R; 18:662293-662293

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.427G>A; p.G143R; 18:662293-662293

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.238T>C; p.F80L; 18:659673-659673

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.612G>A; p.V204V; 18:670747-670747

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.619G>A; p.E207K; 18:670754-670754

 urinary_tract; bladdercarcinomaSubstitution - Missense