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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7189

Name

TRAF6

Synonymous

TNF receptor-associated factor 6, E3 ubiquitin protein ligase;TRAF6;TNF receptor-associated factor 6, E3 ubiquitin protein ligase

Definition

E3 ubiquitin-protein ligase TRAF6|RING finger protein 85|TNF receptor-associated factor 6|interleukin-1 signal transducer

Position

11p12

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.303A>T; p.A101A; 11:36498634-36498634

 bonechondrosarcomaSubstitution - coding silent

c.240A>G; p.A80A; 11:36501276-36501276

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1490G>T; p.C497F; 11:36489917-36489917

 boneosteosarcomaSubstitution - Missense

c.1321C>A; p.P441T; 11:36490086-36490086

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1105G>A; p.E369K; 11:36490302-36490302

 breastcarcinomaSubstitution - Missense

c.557A>G; p.Q186R; 11:36497157-36497157

 breastcarcinomaSubstitution - Missense

c.1174C>T; p.R392C; 11:36490233-36490233

 breastcarcinomaSubstitution - Missense

c.1175G>A; p.R392H; 11:36490232-36490232

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.511A>G; p.K171E; 11:36497203-36497203

 breastcarcinomaSubstitution - Missense

c.448-1G>T; p.?; 11:36497267-36497267

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.635A>G; p.N212S; 11:36495019-36495019

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1003C>T; p.R335*; 11:36490404-36490404

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1486C>T; p.R496C; 11:36489921-36489921

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1303C>A; p.L435I; 11:36490104-36490104

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1032C>T; p.I344I; 11:36490375-36490375

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1032C>T; p.I344I; 11:36490375-36490375

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1193C>T; p.P398L; 11:36490214-36490214

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.764G>T; p.R255M; 11:36490643-36490643

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.668T>C; p.I223T; 11:36494986-36494986

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1214A>G; p.N405S; 11:36490193-36490193

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1105G>A; p.E369K; 11:36490302-36490302

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.815T>C; p.M272T; 11:36490592-36490592

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1264C>A; p.L422I; 11:36490143-36490143

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.564T>C; p.S188S; 11:36497150-36497150

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.729A>G; p.T243T; 11:36492578-36492578

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.729A>G; p.T243T; 11:36492578-36492578

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1003C>T; p.R335*; 11:36490404-36490404

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1194G>A; p.P398P; 11:36490213-36490213

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.995G>A; p.R332Q; 11:36490412-36490412

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.399A>G; p.K133K; 11:36498538-36498538

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.373C>T; p.R125C; 11:36498564-36498564

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.256G>A; p.G86S; 11:36501260-36501260

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.457G>T; p.A153S; 11:36497257-36497257

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.914G>A; p.R305H; 11:36490493-36490493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.865A>G; p.I289V; 11:36490542-36490542

 livercarcinomaSubstitution - Missense

c.377A>G; p.E126G; 11:36498560-36498560

 livercarcinomaSubstitution - Missense

c.377A>G; p.E126G; 11:36498560-36498560

 livercarcinomaSubstitution - Missense

c.767A>G; p.N256S; 11:36490640-36490640

 livercarcinomaSubstitution - Missense

c.767A>G; p.N256S; 11:36490640-36490640

 livercarcinomaSubstitution - Missense

c.767A>G; p.N256S; 11:36490640-36490640

 livercarcinomaSubstitution - Missense

c.99T>C; p.D33D; 11:36501417-36501417

 livercarcinomaSubstitution - coding silent

c.239C>T; p.A80V; 11:36501277-36501277

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.867C>G; p.I289M; 11:36490540-36490540

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.656A>G; p.N219S; 11:36494998-36494998

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.725G>A; p.C242Y; 11:36492582-36492582

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.358G>A; p.D120N; 11:36498579-36498579

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.871G>A; p.E291K; 11:36490536-36490536

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.290C>T; p.S97L; 11:36501226-36501226

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1324G>T; p.V442L; 11:36490083-36490083

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.898C>A; p.H300N; 11:36490509-36490509

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.418T>C; p.L140L; 11:36498519-36498519

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1193C>T; p.P398L; 11:36490214-36490214

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.874G>T; p.V292F; 11:36490533-36490533

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1006A>T; p.T336S; 11:36490401-36490401

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1242G>A; p.M414I; 11:36490165-36490165

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1008C>T; p.T336T; 11:36490399-36490399

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.818T>C; p.L273S; 11:36490589-36490589

 NSmalignant_melanomaSubstitution - Missense

c.541_549delGATTGTCCA; p.D181_P183delDCP; 11:36497165-36497173

 oesophaguscarcinoma; adenocarcinomaDeletion - In frame

c.349C>T; p.L117L; 11:36498588-36498588

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.362A>G; p.N121S; 11:36498575-36498575

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.325A>C; p.N109H; 11:36498612-36498612

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1052G>C; p.G351A; 11:36490355-36490355

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.807C>A; p.H269Q; 11:36490600-36490600

 ovaryother; neoplasmSubstitution - Missense

c.1441G>A; p.A481T; 11:36489966-36489966

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1396C>T; p.R466W; 11:36490011-36490011

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.248C>T; p.T83M; 11:36501268-36501268

 pancreascarcinomaSubstitution - Missense

c.1313C>G; p.S438C; 11:36490094-36490094

 pancreascarcinoma; adenocarcinomaSubstitution - Missense

c.721C>T; p.P241S; 11:36492586-36492586

 skinmalignant_melanomaSubstitution - Missense

c.1126C>T; p.H376Y; 11:36490281-36490281

 skinmalignant_melanomaSubstitution - Missense

c.517C>T; p.H173Y; 11:36497197-36497197

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.517C>T; p.H173Y; 11:36497197-36497197

 skinmalignant_melanomaSubstitution - Missense

c.609C>T; p.I203I; 11:36495045-36495045

 skinmalignant_melanomaSubstitution - coding silent

c.1266C>T; p.L422L; 11:36490141-36490141

 skinmalignant_melanomaSubstitution - coding silent

c.1267C>T; p.P423S; 11:36490140-36490140

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.340G>A; p.E114K; 11:36498597-36498597

 skinmalignant_melanomaSubstitution - Missense

c.1397G>A; p.R466Q; 11:36490010-36490010

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1303C>T; p.L435F; 11:36490104-36490104

 skinmalignant_melanomaSubstitution - Missense

c.1525C>T; p.R509W; 11:36489882-36489882

 skinmalignant_melanomaSubstitution - Missense

c.1225C>T; p.L409F; 11:36490182-36490182

 skinmalignant_melanomaSubstitution - Missense

c.1268C>T; p.P423L; 11:36490139-36490139

 skinmalignant_melanomaSubstitution - Missense

c.665T>C; p.L222P; 11:36494989-36494989

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.345T>A; p.N115K; 11:36498592-36498592

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1557T>C; p.D519D; 11:36489850-36489850

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.943G>A; p.E315K; 11:36490464-36490464

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.842G>A; p.S281N; 11:36490565-36490565

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1193C>T; p.P398L; 11:36490214-36490214

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.301G>A; p.A101T; 11:36498636-36498636

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.19G>A; p.E7K; 11:36501497-36501497

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.762G>A; p.Q254Q; 11:36490645-36490645

 urinary_tract; bladdercarcinomaSubstitution - coding silent