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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7161

Name

TP73

Synonymous

tumor protein p73;TP73;tumor protein p73

Definition

p53-like transcription factor|p53-related protein

Position

1p36.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.101C>T; p.S34L; 1:3683095-3683095

 breastcarcinomaSubstitution - Missense

c.311C>T; p.S104F; 1:3707673-3707673

 breastcarcinomaSubstitution - Missense

c.1174_1175delCA; p.Q392fs*134; 1:3729426-3729427

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.444_446delGAA; p.K150delK; 1:3722035-3722037

 central_nervous_system; parietal_lobeglioma; ependymomaDeletion - In frame

c.444G>C; p.L148F; 1:3722035-3722035

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.35G>A; p.G12D; 1:3682400-3682400

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1196+1delG; p.?; 1:3729449-3729449

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.515G>T; p.G172V; 1:3722106-3722106

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1215G>A; p.P405P; 1:3730018-3730018

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1009G>A; p.V337I; 1:3728152-3728152

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.135G>A; p.T45T; 1:3683129-3683129

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1741C>T; p.R581W; 1:3732909-3732909

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.436C>T; p.P146S; 1:3722027-3722027

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1467C>T; p.A489A; 1:3731048-3731048

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1554C>T; p.Y518Y; 1:3731532-3731532

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.571G>A; p.V191M; 1:3722162-3722162

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.519C>T; p.T173T; 1:3722110-3722110

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.584C>T; p.P195L; 1:3722175-3722175

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.584C>T; p.P195L; 1:3722175-3722175

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.584C>T; p.P195L; 1:3722175-3722175

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.397C>T; p.Q133*; 1:3707759-3707759

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.115A>G; p.N39D; 1:3683109-3683109

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.146T>C; p.M49T; 1:3683140-3683140

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1772G>A; p.R591H; 1:3732940-3732940

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1830G>A; p.A610A; 1:3732998-3732998

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1450C>T; p.P484S; 1:3731031-3731031

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1236G>A; p.S412S; 1:3730039-3730039

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.318C>T; p.F106F; 1:3707680-3707680

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.886G>A; p.A296T; 1:3727671-3727671

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1215G>A; p.P405P; 1:3730018-3730018

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1172A>G; p.Q391R; 1:3729424-3729424

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1172A>G; p.Q391R; 1:3729424-3729424

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1172A>G; p.Q391R; 1:3729424-3729424

 large_intestine; coloncarcinomaSubstitution - Missense

c.1172A>G; p.Q391R; 1:3729424-3729424

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1485-1_1485insT; p.L497fs*30; 1:3731462-3731463

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1736G>A; p.R579H; 1:3732904-3732904

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.330G>A; p.S110S; 1:3707692-3707692

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1170_1172delGCA; p.Q394delQ; 1:3729422-3729424

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - In frame

c.1389C>T; p.N463N; 1:3730970-3730970

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1842C>T; p.F614F; 1:3733010-3733010

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1453delC; p.Y487fs*11; 1:3731034-3731034

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1255delG; p.G420fs*2; 1:3730058-3730058

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1316C>T; p.S439L; 1:3730119-3730119

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.358G>A; p.D120N; 1:3707720-3707720

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1684C>T; p.R562C; 1:3732852-3732852

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1392C>T; p.G464G; 1:3730973-3730973

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1432G>A; p.G478R; 1:3731013-3731013

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1146G>A; p.P382P; 1:3729398-3729398

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.999delC; p.P335fs*10; 1:3728142-3728142

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.999delC; p.P335fs*10; 1:3728142-3728142

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1414G>A; p.A472T; 1:3730995-3730995

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1227G>A; p.P409P; 1:3730030-3730030

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.880A>C; p.I294L; 1:3727665-3727665

 livercarcinomaSubstitution - Missense

c.397C>A; p.Q133K; 1:3707759-3707759

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.790G>T; p.G264W; 1:3727172-3727172

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1172A>G; p.Q391R; 1:3729424-3729424

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1119G>T; p.E373D; 1:3729371-3729371

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1078C>T; p.R360*; 1:3729330-3729330

 lungcarcinoma; small_cell_carcinomaSubstitution - Nonsense

c.179C>G; p.S60C; 1:3683173-3683173

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.647G>T; p.R216L; 1:3723384-3723384

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.163G>A; p.E55K; 1:3683157-3683157

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1684C>T; p.R562C; 1:3732852-3732852

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1502G>T; p.G501V; 1:3731480-3731480

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.89A>C; p.D30A; 1:3683083-3683083

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1009G>A; p.V337I; 1:3728152-3728152

 oesophaguscarcinomaSubstitution - Missense

c.1771C>T; p.R591C; 1:3732939-3732939

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.187-6C>T; p.?; 1:3707543-3707543

 oesophagus; lower_thirdcarcinoma; adenocarcinomaUnknown

c.694G>A; p.G232S; 1:3723431-3723431

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1194G>A; p.R398R; 1:3729446-3729446

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.843-9A>C; p.?; 1:3727619-3727619

 ovaryother; neoplasmUnknown

c.399G>T; p.Q133H; 1:3707761-3707761

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1215G>A; p.P405P; 1:3730018-3730018

 pancreascarcinomaSubstitution - coding silent

c.186+6T>G; p.?; 1:3683186-3683186

 pancreascarcinomaUnknown

c.725C>T; p.P242L; 1:3723462-3723462

 pancreascarcinomaSubstitution - Missense

c.332C>T; p.P111L; 1:3707694-3707694

 prostatecarcinomaSubstitution - Missense

c.604G>A; p.D202N; 1:3722195-3722195

 skinmalignant_melanomaSubstitution - Missense

c.930G>A; p.R310R; 1:3727715-3727715

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1303C>T; p.P435S; 1:3730106-3730106

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1061C>T; p.T354M; 1:3728204-3728204

 skinmalignant_melanomaSubstitution - Missense

c.1518C>G; p.I506M; 1:3731496-3731496

 skinmalignant_melanomaSubstitution - Missense

c.652G>A; p.E218K; 1:3723389-3723389

 skinmalignant_melanomaSubstitution - Missense

c.689T>A; p.V230D; 1:3723426-3723426

 skinmalignant_melanomaSubstitution - Missense

c.510C>T; p.P170P; 1:3722101-3722101

 skinmalignant_melanomaSubstitution - coding silent

c.603G>A; p.R201R; 1:3722194-3722194

 skinmalignant_melanomaSubstitution - coding silent

c.603G>A; p.R201R; 1:3722194-3722194

 skinmalignant_melanomaSubstitution - coding silent

c.135G>A; p.T45T; 1:3683129-3683129

 skinmalignant_melanomaSubstitution - coding silent

c.866C>T; p.S289F; 1:3727651-3727651

 skinmalignant_melanomaSubstitution - Missense

c.1710C>T; p.S570S; 1:3732878-3732878

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1683C>T; p.L561L; 1:3732851-3732851

 skinmalignant_melanomaSubstitution - coding silent

c.1452_1453insC; p.Y487fs*40; 1:3731033-3731034

 skin; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.307A>G; p.S103G; 1:3707669-3707669

 skinmalignant_melanomaSubstitution - Missense

c.708C>T; p.V236V; 1:3723445-3723445

 skinmalignant_melanomaSubstitution - coding silent

c.266A>C; p.H89P; 1:3707628-3707628

 skin; neckmalignant_melanomaSubstitution - Missense

c.1832A>G; p.D611G; 1:3733000-3733000

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.552G>A; p.A184A; 1:3722143-3722143

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.613G>T; p.E205*; 1:3722204-3722204

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.235G>A; p.A79T; 1:3707597-3707597

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.236C>T; p.A79V; 1:3707598-3707598

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.521C>G; p.A174G; 1:3722112-3722112

 stomachadenocarcinomaSubstitution - Missense

c.1254C>T; p.H418H; 1:3730057-3730057

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.567C>T; p.D189D; 1:3722158-3722158

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1053C>T; p.D351D; 1:3728196-3728196

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.314C>T; p.T105I; 1:3707676-3707676

 thyroidcarcinomaSubstitution - Missense

c.119A>G; p.E40G; 1:3683113-3683113

 thyroidcarcinomaSubstitution - Missense

c.225G>A; p.M75I; 1:3707587-3707587

 thyroidcarcinomaSubstitution - Missense

c.702G>A; p.Q234Q; 1:3723439-3723439

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1586G>C; p.G529A; 1:3732754-3732754

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.882C>T; p.I294I; 1:3727667-3727667

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.376C>T; p.H126Y; 1:3707738-3707738

 urinary_tract; bladdercarcinomaSubstitution - Missense