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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7113

Name

TMPRSS2

Synonymous

transmembrane protease, serine 2;TMPRSS2;transmembrane protease, serine 2

Definition

epitheliasin|serine protease 10|transmembrane protease serine 2

Position

21q22.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1254C>T; p.N418N; 21:41468456-41468456

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.80C>T; p.P27L; 21:41494514-41494514

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1241A>T; p.Y414F; 21:41468469-41468469

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.143C>T; p.P48L; 21:41494451-41494451

skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.143C>T; p.P48L; 21:41494451-41494451

skinmalignant_melanomaSubstitution - Missense

c.381C>T; p.I127I; 21:41488458-41488458

upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent