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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

7040

Name

TGFB1

Synonymous

transforming growth factor, beta 1;TGFB1;transforming growth factor, beta 1

Definition

TGF-beta-1|latency-associated peptide|prepro-transforming growth factor beta-1|transforming growth factor beta-1

Position

19q13.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.785C>A; p.A262D; 19:41341958-41341958

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.72C>A; p.G24G; 19:41352973-41352973

 breastcarcinomaSubstitution - coding silent

c.887G>C; p.R296P; 19:41332255-41332255

 breastcarcinomaSubstitution - Missense

c.85G>A; p.G29R; 19:41352960-41352960

 breastcarcinomaSubstitution - Missense

c.713-9delC; p.?; 19:41342039-41342039

 central_nervous_system; braingliomaUnknown

c.713-9delC; p.?; 19:41342039-41342039

 central_nervous_system; cerebrumglioma; astrocytoma_Grade_IVUnknown

c.997G>A; p.D333N; 19:41332145-41332145

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.672C>A; p.S224S; 19:41342210-41342210

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.524G>A; p.S175N; 19:41344857-41344857

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.248G>T; p.S83I; 19:41352797-41352797

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.595G>T; p.D199Y; 19:41344786-41344786

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.570C>T; p.S190S; 19:41344811-41344811

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.99C>T; p.C33C; 19:41352946-41352946

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - coding silent

c.1155C>T; p.R385R; 19:41331070-41331070

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.245_247delACA; p.N82delN; 19:41352798-41352800

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.368A>T; p.K123M; 19:41348443-41348443

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.661G>A; p.A221T; 19:41342221-41342221

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1001C>T; p.T334M; 19:41332141-41332141

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.41C>T; p.P14L; 19:41353004-41353004

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.711C>T; p.N237N; 19:41342171-41342171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.713-9delC; p.?; 19:41342039-41342039

 large_intestine; coloncarcinomaUnknown

c.307T>C; p.Y103H; 19:41352738-41352738

 large_intestine; coloncarcinomaSubstitution - Missense

c.542A>G; p.Y181C; 19:41344839-41344839

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.517-1G>T; p.?; 19:41344865-41344865

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.788C>T; p.T263I; 19:41341955-41341955

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.614G>T; p.R205L; 19:41344767-41344767

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 large_intestineadenomaSubstitution - Missense

c.370T>G; p.F124V; 19:41348441-41348441

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.829C>T; p.R277C; 19:41341914-41341914

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.784G>A; p.A262T; 19:41341959-41341959

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.528C>T; p.N176N; 19:41344853-41344853

 livercarcinomaSubstitution - coding silent

c.528C>T; p.N176N; 19:41344853-41344853

 livercarcinomaSubstitution - coding silent

c.730C>T; p.R244*; 19:41342013-41342013

 lung; left_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.257A>G; p.D86G; 19:41352788-41352788

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.456G>A; p.R152R; 19:41348355-41348355

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.860+1G>T; p.?; 19:41341882-41341882

 lungcarcinoma; adenocarcinomaUnknown

c.601A>T; p.T201S; 19:41344780-41344780

 ovaryother; neoplasmSubstitution - Missense

c.601A>T; p.T201S; 19:41344780-41344780

 ovaryother; neoplasmSubstitution - Missense

c.86G>A; p.G29E; 19:41352959-41352959

 ovaryother; neoplasmSubstitution - Missense

c.713-9delC; p.?; 19:41342039-41342039

 ovarycarcinomaUnknown

c.534C>G; p.S178S; 19:41344847-41344847

 pancreascarcinomaSubstitution - coding silent

c.295C>A; p.P99T; 19:41352750-41352750

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.370T>C; p.F124L; 19:41348441-41348441

 skinmalignant_melanomaSubstitution - Missense

c.934C>T; p.H312Y; 19:41332208-41332208

 skin; acralmalignant_melanomaSubstitution - Missense

c.836C>T; p.A279V; 19:41341907-41341907

 skin; extremitymalignant_melanomaSubstitution - Missense

c.914A>G; p.D305G; 19:41332228-41332228

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.752A>C; p.H251P; 19:41341991-41341991

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.467G>A; p.R156H; 19:41348344-41348344

 stomachadenocarcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 thyroidother; neoplasmSubstitution - Missense

c.629G>A; p.R210H; 19:41344752-41344752

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.29C>T; p.P10L; 19:41353016-41353016

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.606A>G; p.G202G; 19:41344775-41344775

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent