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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

6929

Name

TCF3

Synonymous

transcription factor 3;TCF3;transcription factor 3

Definition

VDR interacting repressor|class B basic helix-loop-helix protein 21|helix-loop-helix protein HE47|immunoglobulin transcription factor 1|kappa-E2-binding factor|negative vitamin D response element-binding protein|transcription factor 3 (E2A immunoglobulin

Position

19p13.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1058C>T; p.P353L; 19:1621003-1621003

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.654T>A; p.D218E; 19:1622222-1622222

 breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.1563G>C; p.L521L; 19:1615709-1615709

 breastcarcinomaSubstitution - coding silent

c.1964G>A; p.*655*; 19:1611708-1611708

 breastcarcinoma; HER-positive_carcinomaSubstitution - coding silent

c.1681C>T; p.R561W; 19:1615426-1615426

 breastcarcinomaSubstitution - Missense

c.503C>T; p.T168M; 19:1623997-1623997

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1357G>A; p.A453T; 19:1619204-1619204

 central_nervous_system; brainstemglioma; oligoastrocytoma_Grade_IIISubstitution - Missense

c.1573C>A; p.R525R; 19:1615699-1615699

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - coding silent

c.256_257delAG; p.S86fs*18; 19:1632079-1632080

 central_nervous_system; brainglioma; astrocytoma_Grade_IVDeletion - Frameshift

c.1172G>C; p.S391T; 19:1619470-1619470

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1172G>C; p.S391T; 19:1619470-1619470

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1861C>T; p.R621*; 19:1611811-1611811

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.936C>T; p.S312S; 19:1621857-1621857

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1699G>A; p.E567K; 19:1615408-1615408

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.423G>A; p.S141S; 19:1625652-1625652

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1819C>T; p.R607*; 19:1615288-1615288

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.319G>A; p.A107T; 19:1627406-1627406

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1714C>A; p.L572M; 19:1615393-1615393

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1792G>A; p.V598I; 19:1615315-1615315

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.1587-1G>A; p.?; 19:1615521-1615521

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaUnknown

c.1675C>T; p.R559W; 19:1615432-1615432

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.764C>A; p.P255Q; 19:1622112-1622112

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.1826G>A; p.R609Q; 19:1611846-1611846

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.1460G>A; p.R487Q; 19:1615812-1615812

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.1820G>A; p.R607Q; 19:1615287-1615287

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.531G>A; p.P177P; 19:1623969-1623969

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.29T>C; p.V10A; 19:1650220-1650220

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.401G>A; p.S134N; 19:1625674-1625674

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1068delC; p.V357fs*37; 19:1620993-1620993

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1068delC; p.V357fs*37; 19:1620993-1620993

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1290C>T; p.T430T; 19:1619352-1619352

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.855T>C; p.G285G; 19:1621938-1621938

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1631C>T; p.A544V; 19:1615476-1615476

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1422C>T; p.D474D; 19:1619139-1619139

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1619delC; p.P540fs*61; 19:1615488-1615488

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1619delC; p.P540fs*61; 19:1615488-1615488

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1236C>T; p.A412A; 19:1619406-1619406

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.479G>T; p.R160I; 19:1625596-1625596

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1111C>T; p.R371*; 19:1619836-1619836

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.503C>T; p.T168M; 19:1623997-1623997

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.23C>T; p.A8V; 19:1650226-1650226

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1308C>T; p.G436G; 19:1619334-1619334

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.G436G; 19:1619334-1619334

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.G436G; 19:1619334-1619334

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.G436G; 19:1619334-1619334

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1308C>T; p.G436G; 19:1619334-1619334

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.882_884delCTC; p.S295delS; 19:1621909-1621911

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1615C>T; p.P539S; 19:1615492-1615492

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.452C>T; p.P151L; 19:1625623-1625623

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.452C>T; p.P151L; 19:1625623-1625623

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1747G>A; p.E583K; 19:1615360-1615360

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1747G>A; p.E583K; 19:1615360-1615360

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1747G>A; p.E583K; 19:1615360-1615360

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.336G>A; p.G112G; 19:1627389-1627389

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.385G>A; p.E129K; 19:1625690-1625690

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.33C>T; p.G11G; 19:1650216-1650216

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.22G>T; p.A8S; 19:1650227-1650227

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.759C>T; p.S253S; 19:1622117-1622117

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.759C>T; p.S253S; 19:1622117-1622117

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.759C>T; p.S253S; 19:1622117-1622117

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.759C>T; p.S253S; 19:1622117-1622117

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1669C>T; p.R557W; 19:1615438-1615438

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1552A>G; p.K518E; 19:1615720-1615720

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1675C>T; p.R559W; 19:1615432-1615432

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1081delC; p.Q361fs*33; 19:1620980-1620980

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.722_723insG; p.G242fs*12; 19:1622153-1622154

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.1530G>A; p.A510A; 19:1615742-1615742

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.209A>G; p.D70G; 19:1632342-1632342

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1819C>T; p.R607*; 19:1615288-1615288

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1589C>G; p.P530R; 19:1615518-1615518

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.314G>A; p.R105Q; 19:1627411-1627411

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1302A>G; p.S434S; 19:1619340-1619340

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.470C>A; p.S157Y; 19:1625605-1625605

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.359T>C; p.L120P; 19:1627366-1627366

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1823-8C>T; p.?; 19:1611857-1611857

 livercarcinoma; hepatocellular_carcinomaUnknown

c.1823-8C>T; p.?; 19:1611857-1611857

 livercarcinoma; hepatocellular_carcinomaUnknown

c.315G>A; p.R105R; 19:1627410-1627410

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.121G>A; p.A41T; 19:1646379-1646379

 livercarcinomaSubstitution - Missense

c.1076C>T; p.S359F; 19:1620985-1620985

 livercarcinomaSubstitution - Missense

c.1076C>T; p.S359F; 19:1620985-1620985

 livercarcinomaSubstitution - Missense

c.1765C>T; p.L589L; 19:1615342-1615342

 livercarcinomaSubstitution - coding silent

c.1765C>T; p.L589L; 19:1615342-1615342

 livercarcinomaSubstitution - coding silent

c.12G>T; p.P4P; 19:1650237-1650237

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1633G>A; p.E545K; 19:1615474-1615474

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.28G>T; p.V10L; 19:1650221-1650221

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1427C>G; p.S476C; 19:1619134-1619134

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.531G>T; p.P177P; 19:1623969-1623969

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1408G>T; p.G470C; 19:1619153-1619153

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.475C>T; p.R159W; 19:1625600-1625600

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1587-8C>T; p.?; 19:1615528-1615528

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.1291_1293GGC>AGT; p.G431S; 19:1619349-1619351

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.59T>G; p.L20R; 19:1650190-1650190

 ovaryother; neoplasmSubstitution - Missense

c.1898C>T; p.P633L; 19:1611774-1611774

 ovaryother; neoplasmSubstitution - Missense

c.1629G>A; p.K543K; 19:1615478-1615478

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.500-1G>A; p.?; 19:1624001-1624001

 skinmalignant_melanomaUnknown

c.1791G>A; p.S597S; 19:1615316-1615316

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1236C>T; p.A412A; 19:1619406-1619406

 skinmalignant_melanomaSubstitution - coding silent

c.955+2_955+3insG; p.?; 19:1621835-1621836

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.135C>T; p.F45F; 19:1646365-1646365

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1837C>T; p.P613S; 19:1611835-1611835

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1919C>T; p.P640L; 19:1611753-1611753

 skinmalignant_melanomaSubstitution - Missense

c.1568C>T; p.A523V; 19:1615704-1615704

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.601C>T; p.P201S; 19:1622364-1622364

 skinmalignant_melanomaSubstitution - Missense

c.496C>T; p.L166L; 19:1625579-1625579

 skinmalignant_melanomaSubstitution - coding silent

c.541C>T; p.P181S; 19:1623959-1623959

 skinmalignant_melanomaSubstitution - Missense

c.998G>A; p.G333D; 19:1621149-1621149

 skinmalignant_melanomaSubstitution - Missense

c.1923C>G; p.H641Q; 19:1611749-1611749

 skinmalignant_melanomaSubstitution - Missense

c.266C>T; p.S89F; 19:1632070-1632070

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1858C>T; p.R620W; 19:1611814-1611814

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1569C>A; p.A523A; 19:1615703-1615703

 skinmalignant_melanomaSubstitution - coding silent

c.222C>T; p.T74T; 19:1632114-1632114

 skinmalignant_melanomaSubstitution - coding silent

c.1472C>T; p.T491M; 19:1615800-1615800

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1924C>G; p.P642A; 19:1611748-1611748

 skinmalignant_melanomaSubstitution - Missense

c.1570C>T; p.P524S; 19:1615702-1615702

 skinmalignant_melanomaSubstitution - Missense

c.1721G>A; p.R574H; 19:1615386-1615386

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1450+1G>A; p.?; 19:1619110-1619110

 stomachcarcinoma; adenocarcinomaUnknown

c.1678C>T; p.L560L; 19:1615429-1615429

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1699G>A; p.E567K; 19:1615408-1615408

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1687C>T; p.R563C; 19:1615420-1615420

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.319G>A; p.A107T; 19:1627406-1627406

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1308C>T; p.G436G; 19:1619334-1619334

 thyroidother; neoplasmSubstitution - coding silent

c.892G>T; p.G298*; 19:1621901-1621901

 thyroidother; neoplasmSubstitution - Nonsense

c.1456G>T; p.G486W; 19:1615816-1615816

 thyroidother; neoplasmSubstitution - Missense

c.314G>A; p.R105Q; 19:1627411-1627411

 thyroidcarcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1459C>G; p.R487G; 19:1615813-1615813

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1948C>A; p.P650T; 19:1611724-1611724

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense