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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

6714

Name

SRC

Synonymous

SRC proto-oncogene, non-receptor tyrosine kinase;SRC;SRC proto-oncogene, non-receptor tyrosine kinase

Definition

proto-oncogene c-Src|proto-oncogene tyrosine-protein kinase Src|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1|v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog

Position

20q12-q13

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1282C>A; p.P428T; 20:37402760-37402760

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.870C>T; p.N290N; 20:37400125-37400125

 breastcarcinomaSubstitution - coding silent

c.651C>T; p.I217I; 20:37396259-37396259

 breastcarcinomaSubstitution - coding silent

c.806C>T; p.S269L; 20:37397801-37397801

 breastcarcinomaSubstitution - Missense

c.1040G>A; p.G347E; 20:37401602-37401602

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1040G>A; p.G347E; 20:37401602-37401602

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.832C>G; p.Q278E; 20:37397827-37397827

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.90C>T; p.G30G; 20:37384243-37384243

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.759G>A; p.P253P; 20:37397754-37397754

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.361T>C; p.W121R; 20:37393905-37393905

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1021A>G; p.T341A; 20:37400276-37400276

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1591C>T; p.Q531*; 20:37403359-37403359

 endometriumcarcinomaSubstitution - Nonsense

c.397G>T; p.G133C; 20:37393941-37393941

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.272C>T; p.A91V; 20:37386096-37386096

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.423G>A; p.A141A; 20:37393967-37393967

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.591C>A; p.A197A; 20:37396199-37396199

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.926C>T; p.A309V; 20:37400181-37400181

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.756G>T; p.K252N; 20:37397751-37397751

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.631G>A; p.D211N; 20:37396239-37396239

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.681G>A; p.Q227Q; 20:37396289-37396289

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.813G>A; p.R271R; 20:37397808-37397808

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1138G>A; p.V380M; 20:37402456-37402456

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.421G>A; p.A141T; 20:37393965-37393965

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.588C>T; p.N196N; 20:37396196-37396196

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.337A>T; p.I113F; 20:37386161-37386161

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.337A>T; p.I113F; 20:37386161-37386161

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1018G>A; p.V340I; 20:37400273-37400273

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.6T>G; p.G2G; 20:37384159-37384159

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.767_768delAG; p.Q256fs*67; 20:37397762-37397763

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.767_768delAG; p.Q256fs*67; 20:37397762-37397763

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.636C>T; p.S212S; 20:37396244-37396244

 large_intestine; colonNSSubstitution - coding silent

c.1081C>A; p.L361M; 20:37401643-37401643

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.750G>A; p.T250T; 20:37397745-37397745

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1219G>A; p.D407N; 20:37402537-37402537

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1571C>T; p.T524M; 20:37403339-37403339

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1460C>T; p.P487L; 20:37403228-37403228

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1591C>T; p.Q531*; 20:37403359-37403359

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1261G>T; p.A421S; 20:37402579-37402579

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.423G>T; p.A141A; 20:37393967-37393967

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1155C>T; p.Y385Y; 20:37402473-37402473

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.51C>T; p.S17S; 20:37384204-37384204

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.330G>A; p.R110R; 20:37386154-37386154

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.423G>A; p.A141A; 20:37393967-37393967

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.423G>A; p.A141A; 20:37393967-37393967

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.464A>G; p.K155R; 20:37394188-37394188

 livercarcinomaSubstitution - Missense

c.405C>T; p.I135I; 20:37393949-37393949

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1402+1G>T; p.?; 20:37402881-37402881

 lungcarcinoma; adenocarcinomaUnknown

c.363G>T; p.W121C; 20:37393907-37393907

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.736A>T; p.T246S; 20:37397731-37397731

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1022C>G; p.T341R; 20:37400277-37400277

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.250+6T>G; p.?; 20:37384409-37384409

 NSNSUnknown

c.1262C>T; p.A421V; 20:37402580-37402580

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.411C>T; p.S137S; 20:37393955-37393955

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1219G>C; p.D407H; 20:37402537-37402537

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1579G>A; p.E527K; 20:37403347-37403347

 pancreascarcinomaSubstitution - Missense

c.1579G>A; p.E527K; 20:37403347-37403347

 pancreascarcinomaSubstitution - Missense

c.703+10C>T; p.?; 20:37396321-37396321

 pancreascarcinomaUnknown

c.346A>G; p.N116D; 20:37386170-37386170

 prostatecarcinomaSubstitution - Missense

c.209C>T; p.S70L; 20:37384362-37384362

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1554C>T; p.F518F; 20:37403322-37403322

 skinmalignant_melanomaSubstitution - coding silent

c.1611G>AA; p.?; 20:37403379-37403380

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.1282C>T; p.P428S; 20:37402760-37402760

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.1024G>A; p.E342K; 20:37400279-37400279

 skinmalignant_melanomaSubstitution - Missense

c.1536C>T; p.F512F; 20:37403304-37403304

 skinmalignant_melanomaSubstitution - coding silent

c.525C>T; p.F175F; 20:37394249-37394249

 skinmalignant_melanomaSubstitution - coding silent

c.1485C>G; p.H495Q; 20:37403253-37403253

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1533C>T; p.T511T; 20:37403301-37403301

 skinmalignant_melanomaSubstitution - coding silent

c.435C>T; p.S145S; 20:37393979-37393979

 skinmalignant_melanomaSubstitution - coding silent

c.60C>T; p.P20P; 20:37384213-37384213

 skinmalignant_melanomaSubstitution - coding silent

c.1017C>T; p.I339I; 20:37400272-37400272

 skinmalignant_melanomaSubstitution - coding silent

c.1017C>T; p.I339I; 20:37400272-37400272

 skinmalignant_melanomaSubstitution - coding silent

c.406C>T; p.P136S; 20:37393950-37393950

 skinmalignant_melanomaSubstitution - Missense

c.1065G>A; p.G355G; 20:37401627-37401627

 skinmalignant_melanomaSubstitution - coding silent

c.1517C>T; p.P506L; 20:37403285-37403285

 skinmalignant_melanomaSubstitution - Missense

c.1517C>T; p.P506L; 20:37403285-37403285

 skinmalignant_melanomaSubstitution - Missense

c.780G>T; p.K260N; 20:37397775-37397775

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.1360C>G; p.L454V; 20:37402838-37402838

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.658C>A; p.R220S; 20:37396266-37396266

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.678G>T; p.L226L; 20:37396286-37396286

 thyroidother; neoplasmSubstitution - coding silent

c.1521G>C; p.E507D; 20:37403289-37403289

 thyroidcarcinomaSubstitution - Missense

c.1218G>C; p.A406A; 20:37402536-37402536

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.76G>A; p.G26S; 20:37384229-37384229

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.541G>A; p.E181K; 20:37394265-37394265

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1171C>T; p.R391C; 20:37402489-37402489

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.17G>A; p.S6N; 20:37384170-37384170

 urinary_tract; bladdercarcinomaSubstitution - Missense