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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

6520

Name

SLC3A2

Synonymous

solute carrier family 3 (amino acid transporter heavy chain), member 2;SLC3A2;solute carrier family 3 (amino acid transporter heavy chain), member 2

Definition

4F2 cell-surface antigen heavy chain|CD98 heavy chain|antigen defined by monoclonal antibody 4F2, heavy chain|antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43|lymphocyte activation antigen 4F2 large subunit|monoclonal antibody 44D7

Position

11q13

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.436C>A; p.L146M; 11:62881063-62881063

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.1116C>T; p.G372G; 11:62884486-62884486

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.26C>T; p.S9L; 11:62856295-62856295

 breastcarcinomaSubstitution - Missense

c.1900C>G; p.R634G; 11:62888607-62888607

 breastcarcinomaSubstitution - Missense

c.1426T>G; p.L476V; 11:62885495-62885495

 breastcarcinomaSubstitution - Missense

c.1170C>T; p.F390F; 11:62884646-62884646

 breastcarcinomaSubstitution - coding silent

c.62G>T; p.G21V; 11:62856331-62856331

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1383G>T; p.W461C; 11:62885345-62885345

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1087G>A; p.D363N; 11:62884457-62884457

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1012G>T; p.D338Y; 11:62882925-62882925

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1819G>A; p.A607T; 11:62888526-62888526

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.903T>C; p.D301D; 11:62881975-62881975

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1767C>A; p.D589E; 11:62888474-62888474

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.724C>T; p.R242C; 11:62881351-62881351

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.1236C>T; p.N412N; 11:62885198-62885198

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1008T>C; p.I336I; 11:62882921-62882921

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.995-13_997del16; p.?; 11:62882895-62882910

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.1025A>G; p.N342S; 11:62882938-62882938

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.37G>A; p.V13M; 11:62856306-62856306

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1058A>G; p.Q353R; 11:62882971-62882971

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1026C>G; p.N342K; 11:62882939-62882939

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1693C>T; p.R565C; 11:62888400-62888400

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1757G>A; p.R586H; 11:62888464-62888464

 large_intestine; coloncarcinomaSubstitution - Missense

c.1757G>A; p.R586H; 11:62888464-62888464

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1757G>A; p.R586H; 11:62888464-62888464

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1759C>A; p.H587N; 11:62888466-62888466

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1901G>A; p.R634H; 11:62888608-62888608

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1243G>A; p.D415N; 11:62885205-62885205

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.910G>A; p.A304T; 11:62881982-62881982

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1345C>T; p.L449L; 11:62885307-62885307

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1649T>C; p.L550P; 11:62888356-62888356

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1806T>C; p.D602D; 11:62888513-62888513

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1603A>C; p.S535R; 11:62888198-62888198

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1663C>T; p.R555W; 11:62888370-62888370

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1226C>T; p.A409V; 11:62885188-62885188

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1226C>T; p.A409V; 11:62885188-62885188

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.985delA; p.K331fs*31; 11:62882057-62882057

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1246C>A; p.L416I; 11:62885208-62885208

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1984T>C; p.*662R; 11:62888691-62888691

 large_intestine; coloncarcinoma; adenocarcinomaNonstop extension

c.1978G>A; p.A660T; 11:62888685-62888685

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1001G>A; p.R334H; 11:62882914-62882914

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1694G>A; p.R565H; 11:62888401-62888401

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1694G>A; p.R565H; 11:62888401-62888401

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1694G>A; p.R565H; 11:62888401-62888401

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1184A>G; p.Q395R; 11:62884660-62884660

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1913C>T; p.S638F; 11:62888620-62888620

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.62G>T; p.G21V; 11:62856331-62856331

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1500G>A; p.G500G; 11:62885569-62885569

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1618G>C; p.V540L; 11:62888213-62888213

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1931G>C; p.R644P; 11:62888638-62888638

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1668G>A; p.R556R; 11:62888375-62888375

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1051T>C; p.S351P; 11:62882964-62882964

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1633G>A; p.E545K; 11:62888340-62888340

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1884C>T; p.L628L; 11:62888591-62888591

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1033G>C; p.G345R; 11:62882946-62882946

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1948C>T; p.H650Y; 11:62888655-62888655

 meningesmeningioma; secretorySubstitution - Missense

c.1214G>A; p.R405K; 11:62884690-62884690

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1656C>T; p.S552S; 11:62888363-62888363

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.507C>T; p.A169A; 11:62881134-62881134

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1249C>G; p.Q417E; 11:62885211-62885211

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1166C>T; p.S389L; 11:62884642-62884642

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.985delA; p.K331fs*31; 11:62882057-62882057

 ovarycarcinoma; serous_carcinomaDeletion - Frameshift

c.1588A>T; p.I530F; 11:62888183-62888183

 pancreascarcinomaSubstitution - Missense

c.600G>A; p.L200L; 11:62881227-62881227

 pancreascarcinomaSubstitution - coding silent

c.139A>G; p.T47A; 11:62870771-62870771

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1725C>T; p.F575F; 11:62888432-62888432

 prostatecarcinomaSubstitution - coding silent

c.958G>A; p.D320N; 11:62882030-62882030

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.157G>A; p.A53T; 11:62870789-62870789

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.319A>G; p.S107G; 11:62876807-62876807

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.319A>G; p.S107G; 11:62876807-62876807

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1006A>C; p.I336L; 11:62882919-62882919

 skinmalignant_melanomaSubstitution - Missense

c.1006A>C; p.I336L; 11:62882919-62882919

 skinmalignant_melanomaSubstitution - Missense

c.673C>T; p.L225F; 11:62881300-62881300

 skinmalignant_melanomaSubstitution - Missense

c.636C>T; p.T212T; 11:62881263-62881263

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1023C>T; p.P341P; 11:62882936-62882936

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1646C>T; p.S549F; 11:62888353-62888353

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1817C>T; p.S606L; 11:62888524-62888524

 skinmalignant_melanomaSubstitution - Missense

c.246C>T; p.L82L; 11:62871617-62871617

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1655C>T; p.S552F; 11:62888362-62888362

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1973_1974CC>TT; p.P658L; 11:62888680-62888681

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1344C>T; p.S448S; 11:62885306-62885306

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.572A>C; p.K191T; 11:62881199-62881199

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.610G>A; p.A204T; 11:62881237-62881237

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1433C>T; p.A478V; 11:62885502-62885502

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1945C>T; p.P649S; 11:62888652-62888652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1392G>A; p.W464*; 11:62885354-62885354

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Nonsense

c.985delA; p.K331fs*31; 11:62882057-62882057

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.1722G>A; p.A574A; 11:62888429-62888429

 thyroidother; neoplasmSubstitution - coding silent

c.1409G>T; p.R470M; 11:62885478-62885478

 thyroidother; neoplasmSubstitution - Missense

c.549G>T; p.E183D; 11:62881176-62881176

 thyroidother; neoplasmSubstitution - Missense

c.190A>G; p.N64D; 11:62870822-62870822

 thyroidother; neoplasmSubstitution - Missense