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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

6016

Name

RIT1

Synonymous

Ras-like without CAAX 1;RIT1;Ras-like without CAAX 1

Definition

GTP-binding protein Rit1|GTP-binding protein Roc1|Ric-like, expressed in many tissues|ras-like protein expressed in many tissues|ras-like without CAAX protein 1

Position

1q22

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.358C>T; p.R120*; 1:155904382-155904382

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Nonsense

c.597C>G; p.P199P; 1:155900451-155900451

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - coding silent

c.414C>G; p.L138L; 1:155904326-155904326

 breastcarcinomaSubstitution - coding silent

c.189T>A; p.R63R; 1:155904779-155904779

 breastcarcinomaSubstitution - coding silent

c.633C>G; p.F211L; 1:155900415-155900415

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.633C>G; p.F211L; 1:155900415-155900415

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.28_30delAGC; p.S10delS; 1:155910732-155910734

 endometriumcarcinoma; endometrioid_carcinomaDeletion - In frame

c.134G>A; p.R45Q; 1:155910479-155910479

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.112A>G; p.T38A; 1:155910501-155910501

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.245T>G; p.F82C; 1:155904495-155904495

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.270G>A; p.M90I; 1:155904470-155904470

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.152A>T; p.D51V; 1:155910461-155910461

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; chronic_myeloid_leukaemiaSubstitution - Missense

c.152A>T; p.D51V; 1:155910461-155910461

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; chronic_myeloid_leukaemiaSubstitution - Missense

c.495_497delTGC; p.A166delA; 1:155900551-155900553

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.220T>A; p.L74M; 1:155904748-155904748

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.107-2A>G; p.?; 1:155910508-155910508

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.646G>T; p.D216Y; 1:155900402-155900402

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.372T>G; p.T124T; 1:155904368-155904368

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.588delA; p.K196fs*12; 1:155900460-155900460

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.483delT; p.F161fs*47; 1:155900565-155900565

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.522T>G; p.V174V; 1:155900526-155900526

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.458C>T; p.A153V; 1:155900590-155900590

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.458C>T; p.A153V; 1:155900590-155900590

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.516T>A; p.D172E; 1:155900532-155900532

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.229G>T; p.A77S; 1:155904739-155904739

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.270G>A; p.M90I; 1:155904470-155904470

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.574G>A; p.A192T; 1:155900474-155900474

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.123C>T; p.F41F; 1:155910490-155910490

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.365G>T; p.R122L; 1:155904375-155904375

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.365G>T; p.R122L; 1:155904375-155904375

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.398G>A; p.G133E; 1:155904342-155904342

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.270G>T; p.M90I; 1:155904470-155904470

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.270G>T; p.M90I; 1:155904470-155904470

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.229G>C; p.A77P; 1:155904739-155904739

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.246T>G; p.F82L; 1:155904494-155904494

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.324C>A; p.F108L; 1:155904416-155904416

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.119A>T; p.Q40L; 1:155910494-155910494

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.364C>T; p.R122*; 1:155904376-155904376

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.503G>A; p.R168H; 1:155900545-155900545

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.365G>A; p.R122Q; 1:155904375-155904375

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.517G>A; p.D173N; 1:155900531-155900531

 pancreascarcinomaSubstitution - Missense

c.259G>A; p.D87N; 1:155904481-155904481

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.67A>G; p.K23E; 1:155910695-155910695

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.334C>T; p.R112C; 1:155904406-155904406

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.334C>T; p.R112C; 1:155904406-155904406

 skinmalignant_melanomaSubstitution - Missense

c.364C>T; p.R122*; 1:155904376-155904376

 skinmalignant_melanomaSubstitution - Nonsense

c.241G>C; p.E81Q; 1:155904499-155904499

 skinmalignant_melanomaSubstitution - Missense

c.101A>C; p.K34T; 1:155910661-155910661

 skinmalignant_melanomaSubstitution - Missense

c.636G>C; p.R212R; 1:155900412-155900412

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.517G>A; p.D173N; 1:155900531-155900531

 skinmalignant_melanomaSubstitution - Missense

c.503G>A; p.R168H; 1:155900545-155900545

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.170C>G; p.A57G; 1:155904798-155904798

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.170C>G; p.A57G; 1:155904798-155904798

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.56C>T; p.S19L; 1:155910706-155910706

 urinary_tract; bladdercarcinomaSubstitution - Missense