Entrez Gene

Basic Information
Gene ID	6015
Name	RING1
Synonymous	ring finger protein 1;RING1;ring finger protein 1
Definition	E3 ubiquitin-protein ligase RING1\|polycomb complex protein RING1\|really interesting new gene 1 protein
Position	6p21.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1166G>A; p.W389*; 6:33212344-33212344	autonomic_ganglia	neuroblastoma	Substitution - Nonsense
c.1004A>G; p.E335G; 6:33211887-33211887	breast	carcinoma	Substitution - Missense
c.238G>T; p.G80W; 6:33209785-33209785	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1017C>T; p.A339A; 6:33211900-33211900	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.234G>A; p.R78R; 6:33209781-33209781	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.898G>A; p.A300T; 6:33211781-33211781	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1055G>A; p.S352N; 6:33211938-33211938	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.501A>C; p.T167T; 6:33211203-33211203	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.436C>T; p.R146C; 6:33210111-33210111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.284G>A; p.R95Q; 6:33209959-33209959	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1029C>T; p.D343D; 6:33211912-33211912	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1065C>T; p.G355G; 6:33211948-33211948	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1065C>T; p.G355G; 6:33211948-33211948	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1065C>T; p.G355G; 6:33211948-33211948	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.238G>A; p.G80R; 6:33209785-33209785	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.53T>G; p.L18R; 6:33208875-33208875	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.755delC; p.S254fs*31; 6:33211457-33211457	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.646delG; p.G217fs*68; 6:33211348-33211348	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.368G>A; p.R123Q; 6:33210043-33210043	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1112C>T; p.A371V; 6:33211995-33211995	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.984A>C; p.G328G; 6:33211867-33211867	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.984A>C; p.G328G; 6:33211867-33211867	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.221T>C; p.V74A; 6:33209768-33209768	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.221T>C; p.V74A; 6:33209768-33209768	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.436C>T; p.R146C; 6:33210111-33210111	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.998G>A; p.G333D; 6:33211881-33211881	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.998G>A; p.G333D; 6:33211881-33211881	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.735delC; p.P247fs*38; 6:33211437-33211437	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.735delC; p.P247fs*38; 6:33211437-33211437	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.743G>T; p.S248I; 6:33211445-33211445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1121C>T; p.T374M; 6:33212299-33212299	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.511delG; p.E173fs*14; 6:33211213-33211213	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.510_511insG; p.E173fs*21; 6:33211212-33211213	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.545A>G; p.D182G; 6:33211247-33211247	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.545A>G; p.D182G; 6:33211247-33211247	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1169A>C; p.K390T; 6:33212347-33212347	liver	carcinoma	Substitution - Missense
c.1107C>A; p.G369G; 6:33211990-33211990	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.394C>T; p.H132Y; 6:33210069-33210069	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.175A>G; p.M59V; 6:33209722-33209722	liver	carcinoma	Substitution - Missense
c.512G>T; p.G171V; 6:33211214-33211214	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.795G>C; p.V265V; 6:33211497-33211497	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.969C>T; p.A323A; 6:33211852-33211852	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.899C>G; p.A300G; 6:33211782-33211782	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.775G>T; p.G259C; 6:33211477-33211477	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.S70F; 6:33209756-33209756	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.263G>T; p.R88L; 6:33209938-33209938	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.329T>G; p.I110S; 6:33210004-33210004	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.745C>T; p.P249S; 6:33211447-33211447	ovary	other; neoplasm	Substitution - Missense
c.593C>T; p.P198L; 6:33211295-33211295	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.313G>A; p.A105T; 6:33209988-33209988	prostate	carcinoma	Substitution - Missense
c.777T>G; p.G259G; 6:33211479-33211479	prostate	carcinoma	Substitution - coding silent
c.341G>A; p.R114Q; 6:33210016-33210016	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.193C>T; p.L65F; 6:33209740-33209740	skin	malignant_melanoma	Substitution - Missense
c.301C>T; p.P101S; 6:33209976-33209976	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.792C>T; p.L264L; 6:33211494-33211494	skin	malignant_melanoma	Substitution - coding silent
c.748C>T; p.P250S; 6:33211450-33211450	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.641G>A; p.G214E; 6:33211343-33211343	skin; extremity	malignant_melanoma	Substitution - Missense
c.877G>A; p.D293N; 6:33211760-33211760	skin	malignant_melanoma	Substitution - Missense
c.877G>A; p.D293N; 6:33211760-33211760	skin	malignant_melanoma	Substitution - Missense
c.342G>A; p.R114R; 6:33210017-33210017	skin	malignant_melanoma	Substitution - coding silent
c.933G>A; p.Q311Q; 6:33211816-33211816	skin	malignant_melanoma	Substitution - coding silent
c.406G>A; p.A136T; 6:33210081-33210081	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.180C>T; p.T60T; 6:33209727-33209727	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.509G>T; p.S170I; 6:33211211-33211211	skin	malignant_melanoma	Substitution - Missense
c.1019G>A; p.G340E; 6:33211902-33211902	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.119G>A; p.R40Q; 6:33209666-33209666	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.238G>A; p.G80R; 6:33209785-33209785	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.314C>T; p.A105V; 6:33209989-33209989	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.570C>T; p.S190S; 6:33211272-33211272	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.621C>T; p.G207G; 6:33211323-33211323	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.869C>T; p.A290V; 6:33211752-33211752	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.517G>A; p.E173K; 6:33211219-33211219	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.284G>A; p.R95Q; 6:33209959-33209959	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.511delG; p.E173fs*14; 6:33211213-33211213	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.583G>A; p.A195T; 6:33211285-33211285	thyroid	other; neoplasm	Substitution - Missense
c.615A>G; p.G205G; 6:33211317-33211317	thyroid	other; neoplasm	Substitution - coding silent
c.1004A>G; p.E335G; 6:33211887-33211887	thyroid	other; neoplasm	Substitution - Missense
c.293G>A; p.R98Q; 6:33209968-33209968	thyroid	carcinoma; medullary_carcinoma	Substitution - Missense
c.1014T>G; p.G338G; 6:33211897-33211897	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1008T>G; p.G336G; 6:33211891-33211891	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004A>G; p.E335G; 6:33211887-33211887	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.611G>T; p.R204L; 6:33211313-33211313	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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