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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

57120

Name

GOPC

Synonymous

golgi-associated PDZ and coiled-coil motif containing;GOPC;golgi-associated PDZ and coiled-coil motif containing

Definition

CFTR-associated ligand|Golgi associated PDZ and coiled-coil motif containing protein|Golgi-associated PDZ and coiled-coil motif-containing protein|PDZ protein interacting specifically with TC10|PDZ/coiled-coil domain binding partner for the rho-family GTP

Position

6q21

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.684G>A; p.M228I; 6:117573599-117573599

 breastcarcinomaSubstitution - Missense

c.807A>C; p.P269P; 6:117573476-117573476

 breastcarcinomaSubstitution - coding silent

c.294G>C; p.L98F; 6:117579056-117579056

 breastcarcinomaSubstitution - Missense

c.853C>A; p.P285T; 6:117570919-117570919

 breastcarcinomaSubstitution - Missense

c.1383_1385delTTA; p.Y462delY; 6:117563258-117563260

 breastcarcinomaDeletion - In frame

c.817G>T; p.D273Y; 6:117570955-117570955

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.537G>T; p.V179V; 6:117575290-117575290

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.257C>T; p.S86F; 6:117602032-117602032

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1259G>T; p.G420V; 6:117563384-117563384

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.490G>A; p.A164T; 6:117575337-117575337

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.773G>T; p.G258V; 6:117573510-117573510

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.14G>A; p.G5D; 6:117602275-117602275

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.351A>T; p.K117N; 6:117578999-117578999

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.816+2T>C; p.?; 6:117573465-117573465

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.50delG; p.G17fs*54; 6:117602239-117602239

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.132T>C; p.A44A; 6:117602157-117602157

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.132T>C; p.A44A; 6:117602157-117602157

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.981C>T; p.C327C; 6:117569668-117569668

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1214G>A; p.G405D; 6:117566898-117566898

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1074G>T; p.Q358H; 6:117569575-117569575

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1021G>A; p.G341R; 6:117569628-117569628

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.761G>A; p.R254Q; 6:117573522-117573522

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1044G>T; p.K348N; 6:117569605-117569605

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.731T>G; p.I244R; 6:117573552-117573552

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.731T>G; p.I244R; 6:117573552-117573552

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.608C>T; p.A203V; 6:117575219-117575219

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1326G>A; p.P442P; 6:117563317-117563317

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.157G>T; p.G53*; 6:117602132-117602132

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1262T>G; p.F421C; 6:117563381-117563381

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.568C>T; p.R190C; 6:117575259-117575259

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.944T>C; p.I315T; 6:117569705-117569705

 livercarcinomaSubstitution - Missense

c.819T>G; p.D273E; 6:117570953-117570953

 livercarcinomaSubstitution - Missense

c.912+5G>T; p.?; 6:117570855-117570855

 livercarcinomaUnknown

c.912+5G>T; p.?; 6:117570855-117570855

 livercarcinomaUnknown

c.462T>A; p.S154S; 6:117577460-117577460

 livercarcinomaSubstitution - coding silent

c.682A>G; p.M228V; 6:117573601-117573601

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1078-1G>C; p.?; 6:117567035-117567035

 lungcarcinoma; adenocarcinomaUnknown

c.645A>C; p.A215A; 6:117575182-117575182

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.487G>C; p.E163Q; 6:117575340-117575340

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1028A>C; p.N343T; 6:117569621-117569621

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.289C>G; p.Q97E; 6:117579061-117579061

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.767G>T; p.C256F; 6:117573516-117573516

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.973G>A; p.D325N; 6:117569676-117569676

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.434C>T; p.T145I; 6:117578916-117578916

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.351A>C; p.K117N; 6:117578999-117578999

 ovarycarcinoma; clear_cell_carcinomaSubstitution - Missense

c.1013C>T; p.A338V; 6:117569636-117569636

 pancreascarcinomaSubstitution - Missense

c.1245C>T; p.I415I; 6:117566867-117566867

 skinmalignant_melanomaSubstitution - coding silent

c.422C>T; p.A141V; 6:117578928-117578928

 skinmalignant_melanomaSubstitution - Missense

c.601T>A; p.Y201N; 6:117575226-117575226

 skinmalignant_melanomaSubstitution - Missense

c.829C>A; p.L277I; 6:117570943-117570943

 skinmalignant_melanomaSubstitution - Missense

c.73C>T; p.P25S; 6:117602216-117602216

 skinmalignant_melanomaSubstitution - Missense

c.588C>T; p.L196L; 6:117575239-117575239

 skinmalignant_melanomaSubstitution - coding silent

c.458C>T; p.P153L; 6:117577464-117577464

 skinmalignant_melanomaSubstitution - Missense

c.761G>A; p.R254Q; 6:117573522-117573522

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.811G>T; p.G271C; 6:117573472-117573472

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1359G>A; p.L453L; 6:117563284-117563284

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.51C>T; p.G17G; 6:117602238-117602238

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1337G>A; p.G446D; 6:117563306-117563306

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1020C>T; p.N340N; 6:117569629-117569629

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.677G>A; p.R226Q; 6:117573606-117573606

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.301C>T; p.L101L; 6:117579049-117579049

 thyroidcarcinomaSubstitution - coding silent