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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

5581

Name

PRKCE

Synonymous

protein kinase C, epsilon;PRKCE;protein kinase C, epsilon

Definition

protein kinase C epsilon type

Position

2p21

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1513G>A; p.D505N; 2:46086283-46086283

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.898G>A; p.A300T; 2:46001478-46001478

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.1438-1G>A; p.?; 2:46086207-46086207

 breastcarcinomaUnknown

c.79C>T; p.H27Y; 2:45652179-45652179

 breastcarcinomaSubstitution - Missense

c.2049A>C; p.P683P; 2:46159734-46159734

 breastcarcinomaSubstitution - coding silent

c.2159T>A; p.I720N; 2:46184826-46184826

 breastcarcinomaSubstitution - Missense

c.695T>G; p.V232G; 2:45984552-45984552

 breastcarcinomaSubstitution - Missense

c.1077T>C; p.L359L; 2:46007475-46007475

 breastcarcinomaSubstitution - coding silent

c.639C>T; p.H213H; 2:45980327-45980327

 breastcarcinomaSubstitution - coding silent

c.1188G>A; p.R396R; 2:46007586-46007586

 breastcarcinomaSubstitution - coding silent

c.1441C>A; p.R481S; 2:46086211-46086211

 breastcarcinomaSubstitution - Missense

c.1653C>T; p.F551F; 2:46145153-46145153

 breastcarcinomaSubstitution - coding silent

c.2160C>T; p.I720I; 2:46184827-46184827

 breastcarcinomaSubstitution - coding silent

c.404C>T; p.S135L; 2:45843055-45843055

 breastcarcinomaSubstitution - Missense

c.943A>G; p.N315D; 2:46001523-46001523

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.916C>A; p.L306M; 2:46001496-46001496

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2105T>G; p.F702C; 2:46184772-46184772

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1114C>T; p.R372*; 2:46007512-46007512

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2068-1G>T; p.?; 2:46184734-46184734

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.1653C>T; p.F551F; 2:46145153-46145153

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.872A>G; p.N291S; 2:46001452-46001452

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.388G>A; p.D130N; 2:45843039-45843039

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.687C>T; p.P229P; 2:45980375-45980375

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1120G>A; p.E374K; 2:46007518-46007518

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1964C>T; p.S655L; 2:46159649-46159649

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1327G>A; p.V443I; 2:46010407-46010407

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1027C>T; p.R343*; 2:46004602-46004602

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.85G>A; p.V29M; 2:45652185-45652185

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.664G>T; p.G222W; 2:45980352-45980352

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.254A>G; p.H85R; 2:45652354-45652354

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.1479delC; p.L494fs*40; 2:46086249-46086249

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - Frameshift

c.1504C>T; p.R502*; 2:46086274-46086274

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.1504C>T; p.R502*; 2:46086274-46086274

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.415C>T; p.P139S; 2:45976431-45976431

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.20T>A; p.L7H; 2:45652120-45652120

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.483G>A; p.R161R; 2:45976499-45976499

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.268G>C; p.G90R; 2:45652368-45652368

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.706C>A; p.R236R; 2:45984563-45984563

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.913G>A; p.D305N; 2:46001493-46001493

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.7G>C; p.V3L; 2:45652107-45652107

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.1833T>C; p.N611N; 2:46151142-46151142

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1512C>T; p.F504F; 2:46086282-46086282

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1512C>T; p.F504F; 2:46086282-46086282

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.485G>A; p.R162H; 2:45976501-45976501

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.123_124CA>AG; p.Y41_I42>*; 2:45652223-45652224

 large_intestine; rectumcarcinoma; adenocarcinomaComplex - deletion inframe

c.1553C>T; p.S518L; 2:46086323-46086323

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1553C>T; p.S518L; 2:46086323-46086323

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.230G>A; p.R77H; 2:45652330-45652330

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1014A>T; p.P338P; 2:46004589-46004589

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.277G>A; p.D93N; 2:45652377-45652377

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.735C>T; p.F245F; 2:45984592-45984592

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.208G>A; p.V70I; 2:45652308-45652308

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1974C>T; p.G658G; 2:46159659-46159659

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.419A>G; p.K140R; 2:45976435-45976435

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.419A>G; p.K140R; 2:45976435-45976435

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1401G>A; p.P467P; 2:46010481-46010481

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2063G>A; p.R688H; 2:46159748-46159748

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.803G>A; p.R268Q; 2:45984660-45984660

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.449G>A; p.R150H; 2:45976465-45976465

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.99G>A; p.P33P; 2:45652199-45652199

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.504C>T; p.N168N; 2:45976520-45976520

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.736G>A; p.G246S; 2:45984593-45984593

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.618C>T; p.C206C; 2:45980306-45980306

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.43G>A; p.A15T; 2:45652143-45652143

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.43G>A; p.A15T; 2:45652143-45652143

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1351G>T; p.D451Y; 2:46010431-46010431

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.71C>T; p.S24L; 2:45652171-45652171

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1818delC; p.F607fs*32; 2:46151127-46151127

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1789A>G; p.M597V; 2:46151098-46151098

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.8T>C; p.V3A; 2:45652108-45652108

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1390C>T; p.R464W; 2:46010470-46010470

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.707G>A; p.R236Q; 2:45984564-45984564

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1373G>T; p.R458M; 2:46010453-46010453

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1816delC; p.F607fs*32; 2:46151125-46151125

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.427G>A; p.E143K; 2:45976443-45976443

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.120C>T; p.P40P; 2:45652220-45652220

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1263+8G>A; p.?; 2:46007669-46007669

 livercarcinomaUnknown

c.1399C>T; p.P467S; 2:46010479-46010479

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1621G>A; p.D541N; 2:46145121-46145121

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2063G>T; p.R688L; 2:46159748-46159748

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.693G>T; p.Q231H; 2:45980381-45980381

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.449G>A; p.R150H; 2:45976465-45976465

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.808G>C; p.G270R; 2:45984665-45984665

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1975G>C; p.E659Q; 2:46159660-46159660

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2180G>T; p.G727V; 2:46184847-46184847

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.929C>T; p.P310L; 2:46001509-46001509

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1115G>A; p.R372Q; 2:46007513-46007513

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.697G>T; p.G233C; 2:45984554-45984554

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1797G>A; p.E599E; 2:46151106-46151106

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1346A>T; p.D449V; 2:46010426-46010426

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1064-10T>G; p.?; 2:46007452-46007452

 oesophaguscarcinoma; adenocarcinomaUnknown

c.237C>T; p.I79I; 2:45652337-45652337

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1453G>A; p.V485I; 2:46086223-46086223

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1452C>T; p.F484F; 2:46086222-46086222

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1319A>G; p.K440R; 2:46010399-46010399

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.590A>C; p.Q197P; 2:45978993-45978993

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1914G>C; p.L638F; 2:46151223-46151223

 ovaryother; neoplasmSubstitution - Missense

c.1297G>C; p.V433L; 2:46010377-46010377

 ovaryother; neoplasmSubstitution - Missense

c.624C>T; p.V208V; 2:45980312-45980312

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1428C>G; p.F476L; 2:46010508-46010508

 ovaryother; neoplasmSubstitution - Missense

c.843C>T; p.H281H; 2:46001423-46001423

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1504C>T; p.R502*; 2:46086274-46086274

 skinmalignant_melanomaSubstitution - Nonsense

c.1391G>A; p.R464Q; 2:46010471-46010471

 skinmalignant_melanomaSubstitution - Missense

c.1701C>T; p.F567F; 2:46145201-46145201

 skinmalignant_melanomaSubstitution - coding silent

c.1374G>A; p.R458R; 2:46010454-46010454

 skinmalignant_melanomaSubstitution - coding silent

c.441C>T; p.F147F; 2:45976457-45976457

 skinmalignant_melanomaSubstitution - coding silent

c.1795G>A; p.E599K; 2:46151104-46151104

 skinmalignant_melanomaSubstitution - Missense

c.466C>G; p.R156G; 2:45976482-45976482

 soft_tissue; blood_vesselangiosarcomaSubstitution - Missense

c.898G>A; p.A300T; 2:46001478-46001478

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2139C>T; p.D713D; 2:46184806-46184806

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1130G>T; p.R377L; 2:46007528-46007528

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.478G>A; p.V160I; 2:45976494-45976494

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1943A>C; p.K648T; 2:46159628-46159628

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1310A>C; p.K437T; 2:46010390-46010390

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1204C>T; p.R402C; 2:46007602-46007602

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.154G>A; p.G52S; 2:45652254-45652254

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1805C>T; p.A602V; 2:46151114-46151114

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.503A>T; p.N168I; 2:45976519-45976519

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1082A>C; p.N361T; 2:46007480-46007480

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1453G>A; p.V485I; 2:46086223-46086223

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1841A>G; p.D614G; 2:46151150-46151150

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1866C>T; p.D622D; 2:46151175-46151175

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.454C>T; p.R152W; 2:45976470-45976470

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.527A>G; p.Y176C; 2:45976543-45976543

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.897C>T; p.I299I; 2:46001477-46001477

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1776C>T; p.A592A; 2:46151085-46151085

 thyroidother; neoplasmSubstitution - coding silent

c.485G>A; p.R162H; 2:45976501-45976501

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.708G>A; p.R236R; 2:45984565-45984565

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1513G>A; p.D505N; 2:46086283-46086283

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.687C>T; p.P229P; 2:45980375-45980375

 urinary_tract; bladdercarcinomaSubstitution - coding silent