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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

55353

Name

LAPTM4B

Synonymous

lysosomal protein transmembrane 4 beta;LAPTM4B;lysosomal protein transmembrane 4 beta

Definition

lysosomal associated protein transmembrane 4 beta|lysosomal-associated transmembrane protein 4B|lysosome-associated transmembrane protein 4-beta

Position

8q22.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.440C>G; p.S147*; 8:97805420-97805420

 breastcarcinomaSubstitution - Nonsense

c.416C>G; p.A139G; 8:97805396-97805396

 breastcarcinomaSubstitution - Missense

c.588C>G; p.F196L; 8:97816087-97816087

 breastcarcinoma; HER-positive_carcinomaSubstitution - Missense

c.676C>G; p.Q226E; 8:97816175-97816175

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.891G>A; p.P297P; 8:97851411-97851411

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.674G>A; p.R225Q; 8:97816173-97816173

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.811T>C; p.Y271H; 8:97825088-97825088

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.500T>C; p.I167T; 8:97815343-97815343

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.503C>T; p.A168V; 8:97815346-97815346

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.288G>A; p.A96A; 8:97776024-97776024

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.684T>C; p.P228P; 8:97819142-97819142

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.572G>A; p.W191*; 8:97816071-97816071

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.428A>G; p.Q143R; 8:97805408-97805408

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.69G>C; p.A23A; 8:97775805-97775805

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.69G>C; p.A23A; 8:97775805-97775805

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.383C>T; p.A128V; 8:97805363-97805363

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.768C>T; p.I256I; 8:97819226-97819226

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.846C>G; p.V282V; 8:97825123-97825123

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.53T>C; p.V18A; 8:97775789-97775789

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.508T>C; p.S170P; 8:97815351-97815351

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.243C>T; p.C81C; 8:97775979-97775979

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.297G>T; p.T99T; 8:97776033-97776033

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.297G>T; p.T99T; 8:97776033-97776033

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.301T>G; p.F101V; 8:97776037-97776037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.939T>G; p.P313P; 8:97851459-97851459

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.933G>A; p.P311P; 8:97851453-97851453

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.504G>A; p.A168A; 8:97815347-97815347

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.511C>G; p.L171V; 8:97815354-97815354

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.69G>C; p.A23A; 8:97775805-97775805

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.527T>A; p.I176K; 8:97815370-97815370

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.97C>A; p.P33T; 8:97775833-97775833

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.10C>T; p.R4W; 8:97775746-97775746

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.703G>A; p.D235N; 8:97819161-97819161

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.647A>T; p.Y216F; 8:97816146-97816146

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.559-5_559-4insA; p.?; 8:97816053-97816054

 NSmalignant_melanomaUnknown

c.522C>T; p.I174I; 8:97815365-97815365

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.477T>G; p.D159E; 8:97805457-97805457

 pancreascarcinomaSubstitution - Missense

c.887C>T; p.P296L; 8:97851407-97851407

 skinmalignant_melanomaSubstitution - Missense

c.402A>T; p.L134F; 8:97805382-97805382

 skin; upper_armmalignant_melanomaSubstitution - Missense

c.570C>T; p.A190A; 8:97816069-97816069

 skinmalignant_melanomaSubstitution - coding silent

c.685C>T; p.P229S; 8:97819143-97819143

 skinmalignant_melanomaSubstitution - Missense

c.814C>T; p.R272*; 8:97825091-97825091

 skinmalignant_melanomaSubstitution - Nonsense

c.485-5G>C; p.?; 8:97815323-97815323

 stomachcarcinoma; adenocarcinomaUnknown

c.540T>C; p.A180A; 8:97815383-97815383

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.421C>G; p.P141A; 8:97805401-97805401

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.503C>T; p.A168V; 8:97815346-97815346

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.950C>T; p.A317V; 8:97851470-97851470

 stomachadenocarcinomaSubstitution - Missense

c.570C>A; p.A190A; 8:97816069-97816069

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 thyroidother; neoplasmSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 thyroidother; neoplasmSubstitution - coding silent

c.30A>G; p.P10P; 8:97775766-97775766

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent