Entrez Gene

Basic Information
Gene ID	5518
Name	PPP2R1A
Synonymous	protein phosphatase 2, regulatory subunit A, alpha;PPP2R1A;protein phosphatase 2, regulatory subunit A, alpha
Definition	PP2A subunit A isoform PR65-alpha\|PP2A subunit A isoform R1-alpha\|medium tumor antigen-associated 61 KDA protein\|protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform\|serine/threonine protein phosphatase 2A, 65 kDa regulatory su
Position	19q13.41
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.415G>A; p.D139N; 19:52211404-52211404	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	breast	carcinoma	Substitution - Missense
c.191A>G; p.E64G; 19:52205984-52205984	breast	carcinoma	Substitution - Missense
c.601G>A; p.V201I; 19:52212783-52212783	breast	carcinoma	Substitution - Missense
c.133G>C; p.E45Q; 19:52201998-52201998	breast	carcinoma	Substitution - Missense
c.509_510insT; p.R171fs*7; 19:52212691-52212692	breast	carcinoma	Insertion - Frameshift
c.1056C>G; p.L352L; 19:52216591-52216591	breast	carcinoma	Substitution - coding silent
c.1752T>G; p.T584T; 19:52225807-52225807	breast	carcinoma	Substitution - coding silent
c.18C>T; p.G6G; 19:52190114-52190114	breast	carcinoma	Substitution - coding silent
c.407delC; p.A136fs*27; 19:52211396-52211396	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.407delC; p.A136fs*27; 19:52211396-52211396	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.993+2T>G; p.?; 19:52216076-52216076	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.1190T>A; p.I397N; 19:52219752-52219752	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.359C>T; p.S120L; 19:52211348-52211348	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>T; p.P179L; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>T; p.P179L; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>T; p.P179L; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>T; p.P179L; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>T; p.P179L; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.661C>T; p.R221W; 19:52212964-52212964	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.121G>A; p.A41T; 19:52201986-52201986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.646G>A; p.E216K; 19:52212828-52212828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1455G>A; p.K485K; 19:52221070-52221070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.544C>T; p.R182W; 19:52212726-52212726	endometrium	carcinoma; mixed_cell_carcinoma	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.710A>G; p.Q237R; 19:52213013-52213013	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.314G>A; p.R105Q; 19:52211303-52211303	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.658G>A; p.V220M; 19:52212961-52212961	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>A; p.S256Y; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>A; p.S256Y; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>A; p.S256Y; 19:52213070-52213070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>A; p.S256Y; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.993G>A; p.K331K; 19:52216074-52216074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.746G>A; p.R249H; 19:52213049-52213049	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.82C>T; p.R28C; 19:52201947-52201947	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.82C>T; p.R28C; 19:52201947-52201947	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.82C>T; p.R28C; 19:52201947-52201947	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>T; p.S256F; 19:52213070-52213070	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.341C>T; p.A114V; 19:52211330-52211330	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.772C>T; p.R258C; 19:52213075-52213075	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.769T>G; p.W257G; 19:52213072-52213072	endometrium	carcinoma; mixed_serous_and_clear_cell_carcinoma	Substitution - Missense
c.769T>G; p.W257G; 19:52213072-52213072	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.406G>A; p.A136T; 19:52211395-52211395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1757T>C; p.L586P; 19:52225968-52225968	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.517C>A; p.L173M; 19:52212699-52212699	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.430C>T; p.R144C; 19:52211419-52211419	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.79-1G>C; p.?; 19:52201943-52201943	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.771G>T; p.W257C; 19:52213074-52213074	endometrium	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.892G>C; p.V298L; 19:52215863-52215863	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.491C>T; p.A164V; 19:52211480-52211480	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; mixed_serous_and_clear_cell_and_mucinous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.894G>A; p.V298V; 19:52215865-52215865	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.770G>A; p.W257*; 19:52213073-52213073	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1123delG; p.D375fs*8; 19:52216658-52216658	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.170-2A>T; p.?; 19:52205961-52205961	kidney	other; neoplasm	Unknown
c.1770A>G; p.*590W; 19:52225981-52225981	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Nonstop extension
c.1514T>C; p.I505T; 19:52221129-52221129	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.553G>A; p.A185T; 19:52212735-52212735	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.84C>T; p.R28R; 19:52201949-52201949	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.547C>T; p.R183W; 19:52212729-52212729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.666G>A; p.L222L; 19:52212969-52212969	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.547C>T; p.R183W; 19:52212729-52212729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.360G>A; p.S120S; 19:52211349-52211349	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.274C>A; p.P92T; 19:52211263-52211263	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1252C>T; p.R418W; 19:52219814-52219814	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1252C>T; p.R418W; 19:52219814-52219814	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1252C>T; p.R418W; 19:52219814-52219814	large_intestine; colon	carcinoma	Substitution - Missense
c.1252C>T; p.R418W; 19:52219814-52219814	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1390A>G; p.S464G; 19:52221005-52221005	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1390A>G; p.S464G; 19:52221005-52221005	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.341C>A; p.A114D; 19:52211330-52211330	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.191A>G; p.E64G; 19:52205984-52205984	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1185T>C; p.I395I; 19:52219747-52219747	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.544C>T; p.R182W; 19:52212726-52212726	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.548G>C; p.R183P; 19:52212730-52212730	large_intestine; colon	carcinoma	Substitution - Missense
c.548G>C; p.R183P; 19:52212730-52212730	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.312G>A; p.V104V; 19:52211301-52211301	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1243G>A; p.A415T; 19:52219805-52219805	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.465delC; p.R157fs*6; 19:52211454-52211454	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.465delC; p.R157fs*6; 19:52211454-52211454	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.400C>T; p.R134W; 19:52211389-52211389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.344T>C; p.I115T; 19:52211333-52211333	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1314C>A; p.F438L; 19:52220200-52220200	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.58C>A; p.L20I; 19:52190154-52190154	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.191A>T; p.E64V; 19:52205984-52205984	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1075G>A; p.D359N; 19:52216610-52216610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1494C>G; p.R498R; 19:52221109-52221109	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1494C>G; p.R498R; 19:52221109-52221109	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1494C>G; p.R498R; 19:52221109-52221109	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.645C>T; p.D215D; 19:52212827-52212827	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.545G>A; p.R182Q; 19:52212727-52212727	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.39C>T; p.I13I; 19:52190135-52190135	liver	carcinoma	Substitution - coding silent
c.39C>T; p.I13I; 19:52190135-52190135	liver	carcinoma	Substitution - coding silent
c.1076A>G; p.D359G; 19:52216611-52216611	liver	carcinoma	Substitution - Missense
c.551C>T; p.A184V; 19:52212733-52212733	liver	carcinoma	Substitution - Missense
c.551C>T; p.A184V; 19:52212733-52212733	liver	carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.87C>T; p.L29L; 19:52201952-52201952	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.547C>T; p.R183W; 19:52212729-52212729	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1228G>T; p.E410*; 19:52219790-52219790	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1227G>T; p.V409V; 19:52219789-52219789	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.420G>T; p.W140C; 19:52211409-52211409	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1177G>C; p.E393Q; 19:52219739-52219739	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.986G>T; p.C329F; 19:52216067-52216067	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1235C>A; p.A412D; 19:52219797-52219797	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1115A>T; p.Q372L; 19:52216650-52216650	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>A; p.D123N; 19:52211356-52211356	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1470C>T; p.S490S; 19:52221085-52221085	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.431G>A; p.R144H; 19:52211420-52211420	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.546G>T; p.R182R; 19:52212728-52212728	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1005C>A; p.S335S; 19:52216540-52216540	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1309G>A; p.E437K; 19:52220195-52220195	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.685G>T; p.V229L; 19:52212988-52212988	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.170-1G>C; p.?; 19:52205962-52205962	lung	carcinoma; adenocarcinoma	Unknown
c.1217C>G; p.P406R; 19:52219779-52219779	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.443G>T; p.C148F; 19:52211432-52211432	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1128+8C>A; p.?; 19:52216671-52216671	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.138G>C; p.R46S; 19:52202003-52202003	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1486C>T; p.L496L; 19:52221101-52221101	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1725C>T; p.V575V; 19:52225780-52225780	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.643G>C; p.D215H; 19:52212825-52212825	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1622C>G; p.A541G; 19:52222202-52222202	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.192G>T; p.E64D; 19:52205985-52205985	lung	carcinoma	Substitution - Missense
c.192G>T; p.E64D; 19:52205985-52205985	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.192G>T; p.E64D; 19:52205985-52205985	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.1591G>C; p.D531H; 19:52222171-52222171	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.444C>T; p.C148C; 19:52211433-52211433	NS	NS	Substitution - coding silent
c.737C>A; p.P246H; 19:52213040-52213040	oesophagus	carcinoma	Substitution - Missense
c.552C>T; p.A184A; 19:52212734-52212734	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.265C>T; p.L89L; 19:52206058-52206058	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1040C>T; p.S347L; 19:52216575-52216575	oesophagus	carcinoma	Substitution - Missense
c.778C>T; p.R260C; 19:52213081-52213081	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	low_malignant_potential_(borderline)_tumour	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; mucinous_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; mucinous_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.298G>A; p.E100K; 19:52211287-52211287	ovary	carcinoma; adenocarcinoma	Substitution - Missense
c.1130G>T; p.C377F; 19:52219692-52219692	ovary	other; neoplasm	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.767C>A; p.S256Y; 19:52213070-52213070	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.772C>T; p.R258C; 19:52213075-52213075	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.433A>C; p.T145P; 19:52211422-52211422	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.769T>G; p.W257G; 19:52213072-52213072	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>G; p.R183G; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.547C>G; p.R183G; 19:52212729-52212729	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.771G>T; p.W257C; 19:52213074-52213074	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.536C>G; p.P179R; 19:52212718-52212718	ovary	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 19:52212729-52212729	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1728A>G; p.K576K; 19:52225783-52225783	pancreas	carcinoma	Substitution - coding silent
c.694G>A; p.A232T; 19:52212997-52212997	pancreas	carcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	prostate	carcinoma	Substitution - Missense
c.889G>A; p.E297K; 19:52215860-52215860	prostate	carcinoma	Substitution - Missense
c.132T>A; p.V44V; 19:52201997-52201997	skin	malignant_melanoma	Substitution - coding silent
c.1510T>A; p.C504S; 19:52221125-52221125	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1252C>T; p.R418W; 19:52219814-52219814	skin	malignant_melanoma	Substitution - Missense
c.437C>T; p.S146L; 19:52211426-52211426	skin; mucosal	malignant_melanoma	Substitution - Missense
c.927C>T; p.F309F; 19:52216008-52216008	skin	malignant_melanoma	Substitution - coding silent
c.162C>T; p.F54F; 19:52202027-52202027	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.177C>T; p.I59I; 19:52205970-52205970	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.469C>T; p.R157*; 19:52211458-52211458	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.456C>T; p.S152S; 19:52211445-52211445	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.725C>T; p.A242V; 19:52213028-52213028	skin	malignant_melanoma	Substitution - Missense
c.359C>T; p.S120L; 19:52211348-52211348	skin	malignant_melanoma	Substitution - Missense
c.656C>T; p.S219L; 19:52212959-52212959	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.428C>T; p.S143F; 19:52211417-52211417	skin	malignant_melanoma	Substitution - Missense
c.511C>T; p.R171W; 19:52212693-52212693	skin	malignant_melanoma	Substitution - Missense
c.1335C>T; p.S445S; 19:52220221-52220221	skin	malignant_melanoma	Substitution - coding silent
c.1108C>T; p.L370L; 19:52216643-52216643	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.615C>T; p.I205I; 19:52212797-52212797	skin	malignant_melanoma	Substitution - coding silent
c.1321G>A; p.E441K; 19:52220207-52220207	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.203C>T; p.A68V; 19:52205996-52205996	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.656C>G; p.S219W; 19:52212959-52212959	skin	malignant_melanoma	Substitution - Missense
c.656C>G; p.S219W; 19:52212959-52212959	skin	malignant_melanoma	Substitution - Missense
c.284C>T; p.S95L; 19:52211273-52211273	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1396C>A; p.L466M; 19:52221011-52221011	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.661C>T; p.R221W; 19:52212964-52212964	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.548G>A; p.R183Q; 19:52212730-52212730	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1303G>A; p.G435R; 19:52220189-52220189	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1006G>A; p.D336N; 19:52216541-52216541	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.544C>T; p.R182W; 19:52212726-52212726	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.825G>A; p.G275G; 19:52215796-52215796	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.583G>A; p.V195M; 19:52212765-52212765	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.463T>A; p.Y155N; 19:52211452-52211452	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.378G>A; p.A126A; 19:52211367-52211367	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.694G>A; p.A232T; 19:52212997-52212997	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1143G>T; p.R381R; 19:52219705-52219705	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1345G>A; p.A449T; 19:52220231-52220231	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.818C>T; p.A273V; 19:52215789-52215789	thyroid	carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	thyroid	other; neoplasm	Substitution - Missense
c.872T>A; p.M291K; 19:52215843-52215843	thyroid	carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1256T>G; p.V419G; 19:52219818-52219818	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1509C>T; p.F503F; 19:52221124-52221124	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.941C>T; p.S314L; 19:52216022-52216022	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1119G>A; p.L373L; 19:52216654-52216654	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.773G>A; p.R258H; 19:52213076-52213076	vulva	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	vulva	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 19:52213076-52213076	vulva	carcinoma; squamous_cell_carcinoma	Substitution - Missense

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COSMIC confirmed somatic mutation [Top]

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