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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

5218

Name

CDK14

Synonymous

cyclin-dependent kinase 14;CDK14;cyclin-dependent kinase 14

Definition

PFTAIRE protein kinase 1|cell division protein kinase 14|serine/threonine-protein kinase PFTAIRE-1

Position

7q21-q22

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.934G>C; p.A312P; 7:90984188-90984188

biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.145G>A; p.E49K; 7:90726642-90726642

breastcarcinomaSubstitution - Missense

c.1101G>T; p.K367N; 7:91112542-91112542

breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.893+1G>A; p.?; 7:90955818-90955818

breastcarcinoma; basal_(triple-negative)_carcinomaUnknown

c.387T>C; p.A129A; 7:90747752-90747752

breastcarcinomaSubstitution - coding silent

c.538G>A; p.D180N; 7:90863222-90863222

breastcarcinomaSubstitution - Missense

c.822G>C; p.V274V; 7:90955746-90955746

breastcarcinomaSubstitution - coding silent

c.327C>T; p.P109P; 7:90747692-90747692

breastcarcinomaSubstitution - coding silent

c.1237G>A; p.D413N; 7:91112678-91112678

breastcarcinomaSubstitution - Missense

c.771C>T; p.F257F; 7:90917723-90917723

breastcarcinomaSubstitution - coding silent

c.384T>C; p.Y128Y; 7:90747749-90747749

central_nervous_system; braingliomaSubstitution - coding silent

c.936T>A; p.A312A; 7:90984190-90984190

central_nervous_system; braingliomaSubstitution - coding silent

c.444C>T; p.I148I; 7:90790606-90790606

cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1135T>C; p.S379P; 7:91112576-91112576

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.185T>A; p.F62Y; 7:90726682-90726682

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1220G>A; p.R407Q; 7:91112661-91112661

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1152T>C; p.C384C; 7:91112593-91112593

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.404A>C; p.K135T; 7:90747769-90747769

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.546C>A; p.I182I; 7:90863230-90863230

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.134A>G; p.D45G; 7:90726631-90726631

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.853C>A; p.L285I; 7:90955777-90955777

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1219C>T; p.R407W; 7:91112660-91112660

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.357G>T; p.K119N; 7:90747722-90747722

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1241-2A>G; p.?; 7:91118063-91118063

endometriumcarcinoma; endometrioid_carcinomaUnknown

c.868G>C; p.E290Q; 7:90955792-90955792

haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.666G>T; p.L222F; 7:90917618-90917618

haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.278A>T; p.E93V; 7:90726775-90726775

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.812C>A; p.S271Y; 7:90955736-90955736

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.746C>A; p.T249K; 7:90917698-90917698

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.70-2A>T; p.?; 7:90726565-90726565

kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.893+1G>T; p.?; 7:90955818-90955818

large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1120G>A; p.A374T; 7:91112561-91112561

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.817G>A; p.E273K; 7:90955741-90955741

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.70A>T; p.I24L; 7:90726567-90726567

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.907A>G; p.I303V; 7:90984161-90984161

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1220G>A; p.R407Q; 7:91112661-91112661

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.613A>C; p.K205Q; 7:90899318-90899318

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.976C>T; p.R326*; 7:90984230-90984230

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.694C>T; p.R232C; 7:90917646-90917646

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.465G>A; p.G155G; 7:90790627-90790627

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.956A>G; p.D319G; 7:90984210-90984210

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.956A>G; p.D319G; 7:90984210-90984210

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.628C>A; p.L210M; 7:90899333-90899333

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.321A>T; p.T107T; 7:90747686-90747686

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.151delA; p.V53fs*20; 7:90726648-90726648

large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.264C>T; p.S88S; 7:90726761-90726761

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1172C>T; p.S391L; 7:91112613-91112613

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.977G>A; p.R326Q; 7:90984231-90984231

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.460G>T; p.E154*; 7:90790622-90790622

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.454_456delGAA; p.E154delE; 7:90790616-90790618

large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.76G>T; p.V26F; 7:90726573-90726573

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.380C>G; p.S127C; 7:90747745-90747745

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1101-2A>T; p.?; 7:91112540-91112540

large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1101-2A>G; p.?; 7:91112540-91112540

large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.749G>T; p.G250V; 7:90917701-90917701

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.816C>T; p.N272N; 7:90955740-90955740

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.714C>T; p.D238D; 7:90917666-90917666

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.622delG; p.L210fs*6; 7:90899327-90899327

large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.671G>A; p.R224Q; 7:90917623-90917623

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.622delG; p.L210fs*6; 7:90899327-90899327

large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.319A>T; p.T107S; 7:90747684-90747684

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.575T>C; p.F192S; 7:90863259-90863259

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1278A>G; p.Q426Q; 7:91118102-91118102

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.444C>A; p.I148I; 7:90790606-90790606

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.747delG; p.E251fs*2; 7:90917699-90917699

large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1101-1G>T; p.?; 7:91112541-91112541

large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.897A>T; p.G299G; 7:90984151-90984151

livercarcinomaSubstitution - coding silent

c.897A>T; p.G299G; 7:90984151-90984151

livercarcinomaSubstitution - coding silent

c.330A>G; p.K110K; 7:90747695-90747695

livercarcinomaSubstitution - coding silent

c.110T>G; p.M37R; 7:90726607-90726607

livercarcinomaSubstitution - Missense

c.110T>G; p.M37R; 7:90726607-90726607

livercarcinomaSubstitution - Missense

c.295C>T; p.R99W; 7:90726792-90726792

livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.411G>A; p.K137K; 7:90790573-90790573

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.955G>A; p.D319N; 7:90984209-90984209

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.376G>T; p.G126*; 7:90747741-90747741

lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1120G>T; p.A374S; 7:91112561-91112561

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.748G>T; p.G250W; 7:90917700-90917700

lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.935C>A; p.A312D; 7:90984189-90984189

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.772G>A; p.G258S; 7:90917724-90917724

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.742G>C; p.D248H; 7:90917694-90917694

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.797C>T; p.P266L; 7:90955721-90955721

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.559A>T; p.T187S; 7:90863243-90863243

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1126G>T; p.D376Y; 7:91112567-91112567

lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1327G>T; p.G443C; 7:91118151-91118151

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.441G>A; p.V147V; 7:90790603-90790603

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.987G>T; p.L329L; 7:90984241-90984241

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1128C>A; p.D376E; 7:91112569-91112569

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.314C>G; p.S105W; 7:90726811-90726811

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.481A>G; p.I161V; 7:90790643-90790643

lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.481A>G; p.I161V; 7:90790643-90790643

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1101G>C; p.K367N; 7:91112542-91112542

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.211C>G; p.Q71E; 7:90726708-90726708

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1310G>A; p.G437E; 7:91118134-91118134

NSmalignant_melanomaSubstitution - Missense

c.1310G>A; p.G437E; 7:91118134-91118134

NSmalignant_melanomaSubstitution - Missense

c.159C>G; p.V53V; 7:90726656-90726656

oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.644T>C; p.V215A; 7:90899349-90899349

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.753G>A; p.E251E; 7:90917705-90917705

oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1100A>C; p.K367T; 7:91079480-91079480

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.131T>G; p.L44R; 7:90726628-90726628

oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1215G>A; p.P405P; 7:91112656-91112656

oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.666G>T; p.L222F; 7:90917618-90917618

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.266C>T; p.S89F; 7:90726763-90726763

oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1208A>G; p.D403G; 7:91112649-91112649

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1242G>A; p.M414I; 7:91118066-91118066

ovarycarcinoma; mucinous_carcinomaSubstitution - Missense

c.1242G>A; p.M414I; 7:91118066-91118066

ovarycarcinoma; mucinous_carcinomaSubstitution - Missense

c.1311G>A; p.G437G; 7:91118135-91118135

skinmalignant_melanomaSubstitution - coding silent

c.1228G>A; p.E410K; 7:91112669-91112669

skinmalignant_melanomaSubstitution - Missense

c.416A>G; p.N139S; 7:90790578-90790578

skinmalignant_melanomaSubstitution - Missense

c.1161G>A; p.K387K; 7:91112602-91112602

skinmalignant_melanomaSubstitution - coding silent

c.1161G>A; p.K387K; 7:91112602-91112602

skinmalignant_melanomaSubstitution - coding silent

c.1137C>A; p.S379S; 7:91112578-91112578

skinmalignant_melanomaSubstitution - coding silent

c.792C>T; p.S264S; 7:90955716-90955716

skinmalignant_melanomaSubstitution - coding silent

c.883C>G; p.L295V; 7:90955807-90955807

skinmalignant_melanomaSubstitution - Missense

c.1101G>A; p.K367K; 7:91112542-91112542

skinmalignant_melanomaSubstitution - coding silent

c.454G>A; p.E152K; 7:90790616-90790616

skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.643G>T; p.V215L; 7:90899348-90899348

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.844C>T; p.P282S; 7:90955768-90955768

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.239A>T; p.N80I; 7:90726736-90726736

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1027C>T; p.H343Y; 7:91045936-91045936

skinmalignant_melanomaSubstitution - Missense

c.1027C>T; p.H343Y; 7:91045936-91045936

skin; extremitymalignant_melanomaSubstitution - Missense

c.505G>A; p.G169R; 7:90863189-90863189

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1192C>T; p.H398Y; 7:91112633-91112633

skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940T>C; p.F314L; 7:90984194-90984194

skinmalignant_melanomaSubstitution - Missense

c.107G>A; p.G36E; 7:90726604-90726604

skinmalignant_melanomaSubstitution - Missense

c.624_625GG>AA; p.G209R; 7:90899329-90899330

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.964G>A; p.D322N; 7:90984218-90984218

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.555G>A; p.K185K; 7:90863239-90863239

skinmalignant_melanomaSubstitution - coding silent

c.1018C>T; p.P340S; 7:91045927-91045927

skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.771C>T; p.F257F; 7:90917723-90917723

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.610G>A; p.D204N; 7:90899315-90899315

skinmalignant_melanomaSubstitution - Missense

c.683A>T; p.Y228F; 7:90917635-90917635

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.244T>C; p.C82R; 7:90726741-90726741

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1312A>G; p.K438E; 7:91118136-91118136

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1032T>A; p.S344S; 7:91045941-91045941

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1300C>T; p.R434W; 7:91118124-91118124

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.470C>A; p.P157H; 7:90790632-90790632

stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.470C>A; p.P157H; 7:90790632-90790632

stomachadenocarcinomaSubstitution - Missense

c.1237G>A; p.D413N; 7:91112678-91112678

stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.467C>T; p.T156I; 7:90790629-90790629

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.697T>C; p.Y233H; 7:90917649-90917649

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1253T>G; p.F418C; 7:91118077-91118077

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.266C>G; p.S89C; 7:90726763-90726763

urinary_tract; bladdercarcinomaSubstitution - Missense

c.635C>T; p.P212L; 7:90899340-90899340

urinary_tract; bladdercarcinomaSubstitution - Missense

c.592G>A; p.D198N; 7:90899297-90899297

urinary_tract; bladdercarcinomaSubstitution - Missense

c.1161G>C; p.K387N; 7:91112602-91112602

urinary_tract; bladdercarcinomaSubstitution - Missense