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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

4791

Name

NFKB2

Synonymous

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100);NFKB2;nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Definition

DNA-binding factor KBF2|NFKB, p52/p100 subunit|lymphocyte translocation chromosome 10 protein|nuclear factor Kappa-B, subunit 2|nuclear factor NF-kappa-B p100 subunit|nuclear factor NF-kappa-B p52 subunit|nuclear factor of Kappa light chain gene enhancer

Position

10q24

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.2679delC; p.Q895fs*>5; 10:102402355-102402355

 autonomic_ganglianeuroblastomaDeletion - Frameshift

c.1406A>T; p.D469V; 10:102399655-102399655

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.2067G>A; p.K689K; 10:102401045-102401045

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.165T>C; p.Y55Y; 10:102396745-102396745

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.830C>T; p.S277F; 10:102398275-102398275

 breastcarcinomaSubstitution - Missense

c.1660_1668delGCTCTGCTG; p.A554_L556delALL; 10:102400353-102400361

 breastcarcinomaDeletion - In frame

c.273C>T; p.I91I; 10:102396933-102396933

 breastcarcinomaSubstitution - coding silent

c.419A>G; p.H140R; 10:102397325-102397325

 breastcarcinomaSubstitution - Missense

c.1798+2T>G; p.?; 10:102400493-102400493

 breastcarcinomaUnknown

c.919C>A; p.L307M; 10:102398451-102398451

 breastcarcinomaSubstitution - Missense

c.262C>T; p.P88S; 10:102396922-102396922

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1017G>T; p.R339R; 10:102398764-102398764

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1093G>A; p.G365R; 10:102398840-102398840

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1617G>A; p.Q539Q; 10:102400310-102400310

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1972C>T; p.R658W; 10:102400950-102400950

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1602G>A; p.A534A; 10:102400295-102400295

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.126C>T; p.I42I; 10:102396471-102396471

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.161G>A; p.R54Q; 10:102396741-102396741

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1091C>T; p.A364V; 10:102398838-102398838

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1757C>T; p.A586V; 10:102400450-102400450

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.781C>T; p.R261W; 10:102398226-102398226

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.2095G>A; p.E699K; 10:102401203-102401203

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1773G>T; p.Q591H; 10:102400466-102400466

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1527T>C; p.Y509Y; 10:102400137-102400137

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2665C>T; p.L889F; 10:102402341-102402341

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.492G>T; p.Q164H; 10:102397398-102397398

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2229G>T; p.K743N; 10:102401454-102401454

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.538G>T; p.E180*; 10:102397562-102397562

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1751G>A; p.S584N; 10:102400444-102400444

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; polycythaemia_veraSubstitution - Missense

c.2094C>T; p.N698N; 10:102401202-102401202

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.590T>C; p.F197S; 10:102397614-102397614

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.2393T>G; p.L798R; 10:102401844-102401844

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.2314G>C; p.D772H; 10:102401765-102401765

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.1051G>A; p.G351R; 10:102398798-102398798

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.300C>T; p.D100D; 10:102396960-102396960

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.1587G>A; p.T529T; 10:102400280-102400280

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.155G>A; p.R52Q; 10:102396735-102396735

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1343C>T; p.A448V; 10:102399592-102399592

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2476G>A; p.G826R; 10:102402057-102402057

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1059C>T; p.G353G; 10:102398806-102398806

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1763C>T; p.A588V; 10:102400456-102400456

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2122delC; p.P709fs*34; 10:102401230-102401230

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2122delC; p.P709fs*34; 10:102401230-102401230

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.68C>A; p.S23Y; 10:102396299-102396299

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2145G>A; p.S715S; 10:102401253-102401253

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2340G>A; p.Q780Q; 10:102401791-102401791

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1957C>A; p.L653M; 10:102400813-102400813

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.874delC; p.Y294fs*4; 10:102398406-102398406

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2350G>A; p.G784R; 10:102401801-102401801

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.203C>T; p.A68V; 10:102396783-102396783

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.2072-1G>T; p.?; 10:102401179-102401179

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1269A>G; p.P423P; 10:102399439-102399439

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2315A>G; p.D772G; 10:102401766-102401766

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1204delG; p.G403fs*79; 10:102399374-102399374

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.457A>C; p.K153Q; 10:102397363-102397363

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1779G>A; p.L593L; 10:102400472-102400472

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2195C>T; p.T732M; 10:102401303-102401303

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1969-2A>G; p.?; 10:102400945-102400945

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1585-10T>A; p.?; 10:102400268-102400268

 livercarcinomaUnknown

c.1585-10T>A; p.?; 10:102400268-102400268

 livercarcinomaUnknown

c.2270C>T; p.P757L; 10:102401495-102401495

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.841G>T; p.V281L; 10:102398286-102398286

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1183A>G; p.M395V; 10:102399353-102399353

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1555G>T; p.V519F; 10:102400165-102400165

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.671G>A; p.G224E; 10:102397990-102397990

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.781C>T; p.R261W; 10:102398226-102398226

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2203G>A; p.D735N; 10:102401311-102401311

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1929G>A; p.E643E; 10:102400785-102400785

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1185G>T; p.M395I; 10:102399355-102399355

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.721C>T; p.R241W; 10:102398040-102398040

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1435C>T; p.H479Y; 10:102399684-102399684

 NSmalignant_melanomaSubstitution - Missense

c.2367C>A; p.G789G; 10:102401818-102401818

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1610C>T; p.T537M; 10:102400303-102400303

 oesophaguscarcinomaSubstitution - Missense

c.39T>A; p.I13I; 10:102396270-102396270

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.362C>A; p.A121D; 10:102397022-102397022

 pancreascarcinomaSubstitution - Missense

c.2477G>A; p.G826E; 10:102402058-102402058

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.1084_1085GG>AA; p.G362N; 10:102398831-102398832

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.368C>T; p.S123F; 10:102397028-102397028

 skinmalignant_melanomaSubstitution - Missense

c.588C>T; p.A196A; 10:102397612-102397612

 skinmalignant_melanomaSubstitution - coding silent

c.307C>T; p.R103C; 10:102396967-102396967

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.307C>T; p.R103C; 10:102396967-102396967

 skinmalignant_melanomaSubstitution - Missense

c.126C>T; p.I42I; 10:102396471-102396471

 skinmalignant_melanomaSubstitution - coding silent

c.2300G>C; p.G767A; 10:102401751-102401751

 skinmalignant_melanomaSubstitution - Missense

c.490C>T; p.Q164*; 10:102397396-102397396

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1995C>T; p.T665T; 10:102400973-102400973

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.752A>G; p.D251G; 10:102398071-102398071

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.805G>A; p.G269R; 10:102398250-102398250

 skin; extremitymalignant_melanomaSubstitution - Missense

c.618C>T; p.S206S; 10:102397642-102397642

 skinmalignant_melanomaSubstitution - coding silent

c.1533C>T; p.I511I; 10:102400143-102400143

 skinmalignant_melanomaSubstitution - coding silent

c.2279C>T; p.P760L; 10:102401504-102401504

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1480C>A; p.L494I; 10:102400090-102400090

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.303A>G; p.P101P; 10:102396963-102396963

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1638G>T; p.L546L; 10:102400331-102400331

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2145G>A; p.S715S; 10:102401253-102401253

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.436A>G; p.M146V; 10:102397342-102397342

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.492G>T; p.Q164H; 10:102397398-102397398

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2094C>T; p.N698N; 10:102401202-102401202

 thyroidother; neoplasmSubstitution - coding silent

c.1821A>G; p.A607A; 10:102400677-102400677

 thyroidother; neoplasmSubstitution - coding silent

c.654T>C; p.H218H; 10:102397678-102397678

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.654T>C; p.H218H; 10:102397678-102397678

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.537A>G; p.K179K; 10:102397561-102397561

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.190G>A; p.G64R; 10:102396770-102396770

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.171T>G; p.C57W; 10:102396751-102396751

 urinary_tract; bladdercarcinomaSubstitution - Missense