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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

4602

Name

MYB

Synonymous

v-myb avian myeloblastosis viral oncogene homolog;MYB;v-myb avian myeloblastosis viral oncogene homolog

Definition

c-myb protein (140 AA)|c-myb10A_CDS|c-myb13A_CDS|c-myb14A_CDS|c-myb8B_CDS|proto-oncogene c-Myb|transcriptional activator Myb

Position

6q22-q23

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1391C>T; p.P464L; 6:135200129-135200129

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.26_27insA; p.Y10fs*2; 6:135185905-135185906

 breastcarcinomaInsertion - Frameshift

c.441G>A; p.W147*; 6:135190261-135190261

 breastcarcinomaSubstitution - Nonsense

c.1212C>G; p.N404K; 6:135198916-135198916

 breastcarcinomaSubstitution - Missense

c.916G>A; p.E306K; 6:135194428-135194428

 breastcarcinomaSubstitution - Missense

c.290_292delAAG; p.E99delE; 6:135189867-135189869

 breastcarcinomaDeletion - In frame

c.418_419insCA; p.E141fs*81; 6:135190238-135190239

 breastcarcinomaInsertion - Frameshift

c.810_823delCAATGTCCCTCAGC; p.N271fs*10; 6:135193885-135193898

 breastcarcinomaDeletion - Frameshift

c.1207T>G; p.L403V; 6:135198911-135198911

 breastcarcinomaSubstitution - Missense

c.308T>C; p.V103A; 6:135190128-135190128

 breastcarcinomaSubstitution - Missense

c.403C>T; p.H135Y; 6:135190223-135190223

 breastcarcinomaSubstitution - Missense

c.281_282insT; p.W95fs*37; 6:135189858-135189859

 breastcarcinomaInsertion - Frameshift

c.601G>T; p.E201*; 6:135192397-135192397

 breastcarcinomaSubstitution - Nonsense

c.850_851delTA; p.Y284fs*1; 6:135194362-135194363

 breastcarcinomaDeletion - Frameshift

c.785C>T; p.P262L; 6:135193860-135193860

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1593A>G; p.E531E; 6:135201644-135201644

 central_nervous_system; braingliomaSubstitution - coding silent

c.769A>G; p.S257G; 6:135193844-135193844

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1019G>A; p.G340E; 6:135195818-135195818

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.901C>T; p.L301F; 6:135194413-135194413

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1705C>A; p.L569I; 6:135203223-135203223

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.187T>C; p.W63R; 6:135187879-135187879

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1597C>T; p.P533S; 6:135201648-135201648

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.104_105insAGC; p.K35_R36insA; 6:135185983-135185984

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaInsertion - In frame

c.105G>T; p.K35N; 6:135185984-135185984

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - Missense

c.345G>A; p.W115*; 6:135190165-135190165

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Nonsense

c.244T>C; p.W82R; 6:135189821-135189821

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.214-1G>C; p.?; 6:135189790-135189790

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisUnknown

c.1595C>T; p.S532F; 6:135201646-135201646

 kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.1025G>A; p.S342N; 6:135195824-135195824

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.727G>T; p.D243Y; 6:135192523-135192523

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.340C>T; p.R114C; 6:135190160-135190160

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.572G>A; p.R191Q; 6:135192368-135192368

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1391C>G; p.P464R; 6:135200129-135200129

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1832C>T; p.A611V; 6:135217889-135217889

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.465T>G; p.I155M; 6:135190285-135190285

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.508G>A; p.A170T; 6:135190328-135190328

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1808C>G; p.P603R; 6:135217865-135217865

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.83G>T; p.G28V; 6:135185962-135185962

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1430A>G; p.Q477R; 6:135200168-135200168

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.341G>A; p.R114H; 6:135190161-135190161

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1443C>T; p.Y481Y; 6:135200181-135200181

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.671C>T; p.A224V; 6:135192467-135192467

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.976G>A; p.G326R; 6:135195775-135195775

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.390T>C; p.C130C; 6:135190210-135190210

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.859G>T; p.E287*; 6:135194371-135194371

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1870A>C; p.S624R; 6:135217927-135217927

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.507C>T; p.I169I; 6:135190327-135190327

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.388T>C; p.C130R; 6:135190208-135190208

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.146A>G; p.E49G; 6:135187838-135187838

 livercarcinomaSubstitution - Missense

c.325A>C; p.K109Q; 6:135190145-135190145

 livercarcinomaSubstitution - Missense

c.325A>C; p.K109Q; 6:135190145-135190145

 livercarcinomaSubstitution - Missense

c.1417G>T; p.A473S; 6:135200155-135200155

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.372G>T; p.G124G; 6:135190192-135190192

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.523G>A; p.G175R; 6:135190343-135190343

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1489G>T; p.D497Y; 6:135200317-135200317

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.116G>C; p.G39A; 6:135185995-135185995

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.933A>T; p.G311G; 6:135194445-135194445

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.389G>A; p.C130Y; 6:135190209-135190209

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.184G>A; p.D62N; 6:135187876-135187876

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1473C>T; p.P491P; 6:135200301-135200301

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.238_240delCAC; p.H80delH; 6:135189815-135189817

 lungcarcinoma; small_cell_carcinomaDeletion - In frame

c.549C>G; p.N183K; 6:135192345-135192345

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.671C>T; p.A224V; 6:135192467-135192467

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.128G>T; p.W43L; 6:135186007-135186007

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.285G>T; p.W95C; 6:135189862-135189862

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1027G>T; p.A343S; 6:135195826-135195826

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1741G>C; p.D581H; 6:135203259-135203259

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1817G>C; p.S606T; 6:135217874-135217874

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1828C>A; p.P610T; 6:135217885-135217885

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.428A>C; p.K143T; 6:135190248-135190248

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1910C>T; p.T637M; 6:135217967-135217967

 oesophaguscarcinomaSubstitution - Missense

c.1464T>C; p.P488P; 6:135200292-135200292

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1707T>A; p.L569L; 6:135203225-135203225

 oesophaguscarcinomaSubstitution - coding silent

c.1000G>A; p.D334N; 6:135195799-135195799

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1677C>T; p.T559T; 6:135201728-135201728

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1540G>C; p.E514Q; 6:135200368-135200368

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.366A>G; p.L122L; 6:135190186-135190186

 pancreascarcinomaSubstitution - coding silent

c.1906C>A; p.R636R; 6:135217963-135217963

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.1670C>T; p.T557M; 6:135201721-135201721

 prostatecarcinomaSubstitution - Missense

c.1142C>T; p.T381I; 6:135195941-135195941

 skinmalignant_melanomaSubstitution - Missense

c.1142C>T; p.T381I; 6:135195941-135195941

 skinmalignant_melanomaSubstitution - Missense

c.734C>T; p.S245F; 6:135192530-135192530

 skinmalignant_melanomaSubstitution - Missense

c.1567C>A; p.L523M; 6:135200395-135200395

 skinmalignant_melanomaSubstitution - Missense

c.999C>T; p.A333A; 6:135195798-135195798

 skinmalignant_melanomaSubstitution - coding silent

c.1161delG; p.N388fs*3; 6:135195960-135195960

 skin; head_neckcarcinoma; squamous_cell_carcinomaDeletion - Frameshift

c.494G>A; p.R165K; 6:135190314-135190314

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.91C>T; p.P31S; 6:135185970-135185970

 skinmalignant_melanomaSubstitution - Missense

c.992C>T; p.T331I; 6:135195791-135195791

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.437C>T; p.S146F; 6:135190257-135190257

 skinmalignant_melanomaSubstitution - Missense

c.816C>T; p.V272V; 6:135193891-135193891

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1394G>A; p.R465K; 6:135200132-135200132

 skinmalignant_melanomaSubstitution - Missense

c.1716C>T; p.S572S; 6:135203234-135203234

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1561C>T; p.P521S; 6:135200389-135200389

 skinmalignant_melanomaSubstitution - Missense

c.1171G>T; p.E391*; 6:135195970-135195970

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1000G>A; p.D334N; 6:135195799-135195799

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.642C>T; p.F214F; 6:135192438-135192438

 skinmalignant_melanomaSubstitution - coding silent

c.888G>A; p.K296K; 6:135194400-135194400

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.53A>C; p.D18A; 6:135185932-135185932

 skinmalignant_melanomaSubstitution - Missense

c.1128C>T; p.I376I; 6:135195927-135195927

 skinmalignant_melanomaSubstitution - coding silent

c.1128C>T; p.I376I; 6:135195927-135195927

 skinmalignant_melanomaSubstitution - coding silent

c.1128C>T; p.I376I; 6:135195927-135195927

 skinmalignant_melanomaSubstitution - coding silent

c.632C>T; p.A211V; 6:135192428-135192428

 skinmalignant_melanomaSubstitution - Missense

c.1071G>A; p.L357L; 6:135195870-135195870

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1917C>A; p.V639V; 6:135217974-135217974

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.106C>T; p.R36C; 6:135185985-135185985

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.806T>C; p.I269T; 6:135193881-135193881

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1228G>A; p.E410K; 6:135198932-135198932

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1529G>A; p.G510E; 6:135200357-135200357

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.421G>C; p.E141Q; 6:135190241-135190241

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1272C>T; p.L424L; 6:135198976-135198976

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1272C>T; p.L424L; 6:135198976-135198976

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1868C>T; p.S623F; 6:135217925-135217925

 urinary_tract; bladdercarcinomaSubstitution - Missense