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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

4440

Name

MSI1

Synonymous

musashi RNA-binding protein 1;MSI1;musashi RNA-binding protein 1

Definition

RNA-binding protein Musashi homolog 1|musashi-1|musashi1

Position

12q24

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.142G>A; p.E48K; 12:120368232-120368232

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.574C>T; p.P192S; 12:120356980-120356980

 breastcarcinomaSubstitution - Missense

c.718A>C; p.T240P; 12:120353314-120353314

 breastcarcinomaSubstitution - Missense

c.685A>C; p.S229R; 12:120353347-120353347

 breastcarcinomaSubstitution - Missense

c.478G>C; p.E160Q; 12:120357872-120357872

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.195C>T; p.F65F; 12:120368080-120368080

 breastcarcinomaSubstitution - coding silent

c.298G>A; p.A100T; 12:120364725-120364725

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.500G>A; p.C167Y; 12:120357850-120357850

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.378G>A; p.K126K; 12:120363067-120363067

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.828A>G; p.A276A; 12:120347477-120347477

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.197T>C; p.V66A; 12:120368078-120368078

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.420G>A; p.L140L; 12:120359036-120359036

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.808T>G; p.Y270D; 12:120347497-120347497

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.1050C>T; p.G350G; 12:120345630-120345630

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.319C>T; p.R107*; 12:120363126-120363126

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.842C>G; p.A281G; 12:120347463-120347463

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.681C>T; p.Y227Y; 12:120353351-120353351

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - coding silent

c.732C>T; p.P244P; 12:120353300-120353300

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.254T>G; p.L85R; 12:120368021-120368021

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.217G>C; p.G73R; 12:120368058-120368058

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.658C>T; p.P220S; 12:120353374-120353374

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.669_670insA; p.A224fs*>140; 12:120353362-120353363

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.578C>T; p.T193M; 12:120356976-120356976

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.468G>A; p.T156T; 12:120357882-120357882

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.738C>T; p.F246F; 12:120351396-120351396

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.479A>G; p.E160G; 12:120357871-120357871

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.561G>T; p.K187N; 12:120356993-120356993

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.501T>G; p.C167W; 12:120357849-120357849

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.298G>A; p.A100T; 12:120364725-120364725

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.810C>T; p.Y270Y; 12:120347495-120347495

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.372C>T; p.D124D; 12:120363073-120363073

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.923T>A; p.L308Q; 12:120346259-120346259

 livercarcinomaSubstitution - Missense

c.828A>G; p.A276A; 12:120347477-120347477

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.303G>T; p.Q101H; 12:120364720-120364720

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.230T>G; p.V77G; 12:120368045-120368045

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.786T>C; p.L262L; 12:120351348-120351348

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.354G>A; p.V118V; 12:120363091-120363091

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.682G>T; p.A228S; 12:120353350-120353350

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.271G>A; p.D91N; 12:120364752-120364752

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1077T>C; p.N359N; 12:120345603-120345603

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.238C>T; p.Q80*; 12:120368037-120368037

 oesophagus; upper_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.457G>A; p.G153R; 12:120357893-120357893

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.894T>C; p.G298G; 12:120346288-120346288

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.216G>A; p.A72A; 12:120368059-120368059

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.259T>C; p.S87P; 12:120368016-120368016

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.566T>C; p.V189A; 12:120356988-120356988

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.638G>A; p.G213D; 12:120356916-120356916

 pancreascarcinomaSubstitution - Missense

c.638G>A; p.G213D; 12:120356916-120356916

 pancreascarcinomaSubstitution - Missense

c.340G>T; p.G114W; 12:120363105-120363105

 pancreascarcinomaSubstitution - Missense

c.456C>T; p.F152F; 12:120357894-120357894

 pancreascarcinomaSubstitution - coding silent

c.678C>A; p.T226T; 12:120353354-120353354

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.398G>A; p.G133E; 12:120363047-120363047

 skinmalignant_melanomaSubstitution - Missense

c.398G>A; p.G133E; 12:120363047-120363047

 skinmalignant_melanomaSubstitution - Missense

c.267+10C>T; p.?; 12:120367998-120367998

 skin; armmalignant_melanomaUnknown

c.60-2A>T; p.?; 12:120368875-120368875

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.267+9C>T; p.?; 12:120367999-120367999

 skin; armmalignant_melanomaUnknown

c.545A>C; p.K182T; 12:120357009-120357009

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.861C>T; p.G287G; 12:120346321-120346321

 skinmalignant_melanomaSubstitution - coding silent

c.288C>T; p.F96F; 12:120364735-120364735

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.705C>T; p.L235L; 12:120353327-120353327

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.938C>T; p.P313L; 12:120346244-120346244

 skinmalignant_melanomaSubstitution - Missense

c.761C>A; p.P254Q; 12:120351373-120351373

 skinmalignant_melanomaSubstitution - Missense

c.546G>A; p.K182K; 12:120357008-120357008

 skinmalignant_melanomaSubstitution - coding silent

c.684C>T; p.A228A; 12:120353348-120353348

 skinmalignant_melanomaSubstitution - coding silent

c.840G>A; p.A280A; 12:120347465-120347465

 skinmalignant_melanomaSubstitution - coding silent

c.130G>A; p.G44R; 12:120368244-120368244

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1050C>T; p.G350G; 12:120345630-120345630

 skinmalignant_melanomaSubstitution - coding silent

c.652+1G>A; p.?; 12:120356901-120356901

 skinmalignant_melanomaUnknown

c.588C>T; p.A196A; 12:120356966-120356966

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.669_670insA; p.A224fs*>140; 12:120353362-120353363

 stomachcarcinoma; diffuse_adenocarcinomaInsertion - Frameshift

c.1081T>C; p.Y361H; 12:120345599-120345599

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.524A>G; p.N175S; 12:120357826-120357826

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.981G>A; p.S327S; 12:120346201-120346201

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.293G>A; p.R98Q; 12:120364730-120364730

 thyroidcarcinomaSubstitution - Missense

c.549A>C; p.K183N; 12:120357005-120357005

 thyroidcarcinomaSubstitution - Missense

c.163C>A; p.P55T; 12:120368211-120368211

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense