Entrez Gene

Basic Information
Gene ID	4352
Name	MPL
Synonymous	MPL proto-oncogene, thrombopoietin receptor;MPL;MPL proto-oncogene, thrombopoietin receptor
Definition	TPO-R\|myeloproliferative leukemia protein\|myeloproliferative leukemia virus oncogene\|proto-oncogene c-Mpl\|thrombopoietin receptor
Position	1p34
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.169G>A; p.A57T; 1:43338188-43338188	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1824A>C; p.P608P; 1:43352688-43352688	breast	carcinoma	Substitution - coding silent
c.1574G>A; p.R525K; 1:43352224-43352224	breast	carcinoma	Substitution - Missense
c.1492C>G; p.L498V; 1:43349286-43349286	breast	carcinoma	Substitution - Missense
c.856G>T; p.A286S; 1:43340389-43340389	breast	carcinoma	Substitution - Missense
c.269G>A; p.R90Q; 1:43338598-43338598	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1649G>A; p.S550N; 1:43352299-43352299	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1168C>T; p.R390C; 1:43346794-43346794	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.62C>T; p.A21V; 1:43337910-43337910	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.289G>T; p.D97Y; 1:43338618-43338618	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.795C>T; p.L265L; 1:43340068-43340068	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1857C>A; p.T619T; 1:43352721-43352721	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.10T>C; p.W4R; 1:43337858-43337858	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1778G>T; p.R593I; 1:43352642-43352642	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1014G>T; p.E338D; 1:43346478-43346478	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.649C>T; p.P217S; 1:43339528-43339528	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.475C>A; p.P159T; 1:43339354-43339354	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.962G>A; p.R321Q; 1:43340495-43340495	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.962G>A; p.R321Q; 1:43340495-43340495	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.962G>A; p.R321Q; 1:43340495-43340495	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1003G>A; p.E335K; 1:43346467-43346467	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	other; splanchnic_vein_thrombosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>AA; p.W515K; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1886_1887insGG; p.S630fs*8; 1:43352750-43352751	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; mast_cell_neoplasm	Insertion - Frameshift
c.1634A>G; p.D545G; 1:43352284-43352284	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1633G>A; p.D545N; 1:43352283-43352283	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1501G>C; p.V501L; 1:43349295-43349295	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1556C>T; p.A519V; 1:43349350-43349350	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1519G>A; p.V507I; 1:43349313-43349313	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1886T>C; p.L629P; 1:43352750-43352750	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1525G>T; p.G509C; 1:43349319-43349319	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1514G>A; p.S505N; 1:43349308-43349308	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.953G>T; p.S318I; 1:43340486-43340486	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Substitution - Missense
c.1433C>A; p.S478*; 1:43348967-43348967	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Nonsense
c.1529T>C; p.L510P; 1:43349323-43349323	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>C; p.W515S; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>C; p.W515S; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1870C>G; p.H624D; 1:43352734-43352734	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1775G>A; p.R592Q; 1:43352639-43352639	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1539_1540ins12; p.L513_R514insLSCL; 1:43349333-43349334	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Insertion - In frame
c.610T>C; p.S204P; 1:43339489-43339489	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1513A>T; p.S505C; 1:43349307-43349307	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1559A>C; p.H520P; 1:43349353-43349353	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1489G>A; p.A497T; 1:43349283-43349283	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1491_1492ins12; p.A497_L498insLVIA; 1:43349285-43349286	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Insertion - In frame
c.1488_1489ins12; p.T496_A497insALVI; 1:43349282-43349283	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Insertion - In frame
c.1694C>T; p.P565L; 1:43352558-43352558	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1543_1552TGGCAGTTTC>AAAA; p.W515_P518>KT; 1:43349337-43349346	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Complex - deletion inframe
c.1543_1552TGGCAGTTTC>AAAA; p.W515_P518>KT; 1:43349337-43349346	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Complex - deletion inframe
c.1216C>G; p.L406V; 1:43346842-43346842	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543T>A; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1516G>A; p.A506T; 1:43349310-43349310	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1516G>A; p.A506T; 1:43349310-43349310	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1542_1544GTG>AGC; p.W515A; 1:43349336-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1759G>A; p.A587T; 1:43352623-43352623	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1543T>C; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Substitution - Missense
c.1543T>C; p.W515R; 1:43349337-43349337	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1892delA; p.Y631fs*>5; 1:43352756-43352756	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Deletion - Frameshift
c.1183A>G; p.N395D; 1:43346809-43346809	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; chronic_myelomonocytic_leukaemia	Substitution - Missense
c.1771T>G; p.Y591D; 1:43352635-43352635	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1771T>G; p.Y591D; 1:43352635-43352635	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; polycythaemia_vera	Substitution - Missense
c.1771T>G; p.Y591D; 1:43352635-43352635	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1541G>A; p.R514K; 1:43349335-43349335	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.899C>G; p.T300S; 1:43340432-43340432	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.404C>G; p.P135R; 1:43339283-43339283	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic-myeloproliferative_neoplasm-unclassifiable	Substitution - Missense
c.754T>C; p.Y252H; 1:43340027-43340027	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1555G>A; p.A519T; 1:43349349-43349349	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1555G>A; p.A519T; 1:43349349-43349349	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.?; p.?; 1:43349364-43349364	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Unknown
c.1543_1545TGG>AAA; p.W515K; 1:43349337-43349339	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1545TGG>AAA; p.W515K; 1:43349337-43349339	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1543_1544TG>GC; p.W515A; 1:43349337-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1053C>T; p.R351R; 1:43346517-43346517	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_leukaemic_transformation_of_essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1502T>C; p.V501A; 1:43349296-43349296	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_leukaemic_transformation_of_primary_myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1573_1574AG>T; p.R525fs*15; 1:43352223-43352224	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Complex - frameshift
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_leukaemic_transformation_of_essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelodysplastic_syndrome	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1502T>C; p.V501A; 1:43349296-43349296	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1544G>T; p.W515L; 1:43349338-43349338	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.1618G>A; p.G540S; 1:43352268-43352268	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myeloproliferative_neoplasm	Substitution - Missense
c.?; p.?; 1:43352306-43352306	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Unknown
c.1120A>G; p.T374A; 1:43346584-43346584	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1367G>A; p.R456H; 1:43348901-43348901	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1459A>G; p.T487A; 1:43348993-43348993	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.611C>T; p.S204F; 1:43339490-43339490	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; myelofibrosis	Substitution - Missense
c.1524G>T; p.L508L; 1:43349318-43349318	kidney	other; neoplasm	Substitution - coding silent
c.1165+2T>C; p.?; 1:43346631-43346631	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1660G>A; p.A554T; 1:43352524-43352524	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1632G>T; p.R544S; 1:43352282-43352282	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1513A>G; p.S505G; 1:43349307-43349307	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.61G>T; p.A21S; 1:43337909-43337909	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.610T>C; p.S204P; 1:43339489-43339489	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1515C>T; p.S505S; 1:43349309-43349309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.253C>T; p.P85S; 1:43338582-43338582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.399G>A; p.P133P; 1:43339278-43339278	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1326_1327insG; p.A444fs*39; 1:43348860-43348861	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1168C>T; p.R390C; 1:43346794-43346794	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.509G>A; p.R170H; 1:43339388-43339388	large_intestine; rectum	NS	Substitution - Missense
c.713G>A; p.G238D; 1:43339986-43339986	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.853G>T; p.V285L; 1:43340126-43340126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.612T>C; p.S204S; 1:43339491-43339491	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.612T>C; p.S204S; 1:43339491-43339491	large_intestine; rectum	NS	Substitution - coding silent
c.414C>A; p.I138I; 1:43339293-43339293	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1111G>A; p.A371T; 1:43346575-43346575	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1541G>T; p.R514M; 1:43349335-43349335	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1541G>T; p.R514M; 1:43349335-43349335	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.500A>G; p.Y167C; 1:43339379-43339379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.777A>G; p.E259E; 1:43340050-43340050	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.501C>T; p.Y167Y; 1:43339380-43339380	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.501C>T; p.Y167Y; 1:43339380-43339380	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1367G>T; p.R456L; 1:43348901-43348901	liver	carcinoma	Substitution - Missense
c.1002C>A; p.C334*; 1:43346466-43346466	liver	carcinoma	Substitution - Nonsense
c.1002C>A; p.C334*; 1:43346466-43346466	liver	carcinoma	Substitution - Nonsense
c.507C>A; p.L169L; 1:43339386-43339386	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1774C>T; p.R592*; 1:43352638-43352638	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1122T>A; p.T374T; 1:43346586-43346586	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1670C>G; p.S557*; 1:43352534-43352534	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1670C>G; p.S557*; 1:43352534-43352534	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.584C>A; p.P195H; 1:43339463-43339463	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.757T>C; p.W253R; 1:43340030-43340030	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1014G>C; p.E338D; 1:43346478-43346478	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1116G>C; p.P372P; 1:43346580-43346580	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1039C>A; p.P347T; 1:43346503-43346503	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.695C>G; p.S232*; 1:43339968-43339968	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.1801A>G; p.T601A; 1:43352665-43352665	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.598C>A; p.P200T; 1:43339477-43339477	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.366G>A; p.Q122Q; 1:43338695-43338695	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.500A>G; p.Y167C; 1:43339379-43339379	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1528_1530delCTG; p.L513delL; 1:43349322-43349324	NS	malignant_melanoma	Deletion - In frame
c.632G>C; p.C211S; 1:43339511-43339511	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1359G>A; p.P453P; 1:43348893-43348893	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1593A>C; p.S531S; 1:43352243-43352243	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.209C>T; p.P70L; 1:43338228-43338228	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.21C>G; p.F7L; 1:43337869-43337869	ovary	other; neoplasm	Substitution - Missense
c.999C>T; p.N333N; 1:43346463-43346463	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1270C>T; p.Q424*; 1:43346896-43346896	pancreas	NS	Substitution - Nonsense
c.888G>A; p.L296L; 1:43340421-43340421	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.538A>T; p.T180S; 1:43339417-43339417	skin	malignant_melanoma	Substitution - Missense
c.157G>A; p.D53N; 1:43338176-43338176	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1672G>A; p.D558N; 1:43352536-43352536	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.15C>T; p.A5A; 1:43337863-43337863	skin	malignant_melanoma	Substitution - coding silent
c.508C>T; p.R170C; 1:43339387-43339387	skin	malignant_melanoma	Substitution - Missense
c.510C>T; p.R170R; 1:43339389-43339389	skin	malignant_melanoma	Substitution - coding silent
c.677C>T; p.S226F; 1:43339556-43339556	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.932C>T; p.S311F; 1:43340465-43340465	skin	malignant_melanoma	Substitution - Missense
c.845G>A; p.G282E; 1:43340118-43340118	skin	malignant_melanoma	Substitution - Missense
c.483C>T; p.I161I; 1:43339362-43339362	skin	malignant_melanoma	Substitution - coding silent
c.297G>A; p.E99E; 1:43338626-43338626	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1070G>A; p.R357Q; 1:43346534-43346534	skin	malignant_melanoma	Substitution - Missense
c.312C>T; p.F104F; 1:43338641-43338641	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.21C>T; p.F7F; 1:43337869-43337869	skin	malignant_melanoma	Substitution - coding silent
c.1799G>A; p.G600E; 1:43352663-43352663	skin	malignant_melanoma	Substitution - Missense
c.1800G>A; p.G600G; 1:43352664-43352664	skin	malignant_melanoma	Substitution - coding silent
c.1286G>A; p.G429E; 1:43346912-43346912	skin	malignant_melanoma	Substitution - Missense
c.616C>T; p.L206L; 1:43339495-43339495	skin; arm	malignant_melanoma	Substitution - coding silent
c.242C>T; p.S81F; 1:43338571-43338571	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.214G>A; p.E72K; 1:43338543-43338543	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.606A>G; p.S202S; 1:43339485-43339485	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.769C>T; p.R257C; 1:43340042-43340042	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.142C>A; p.L48I; 1:43338161-43338161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1652C>T; p.P551L; 1:43352302-43352302	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.224G>A; p.R75H; 1:43338553-43338553	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1697G>A; p.S566N; 1:43352561-43352561	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.274G>A; p.V92M; 1:43338603-43338603	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.86C>A; p.S29Y; 1:43338105-43338105	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1498C>G; p.L500V; 1:43349292-43349292	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.211C>T; p.R71W; 1:43338230-43338230	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.561G>A; p.L187L; 1:43339440-43339440	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.326T>A; p.L109H; 1:43338655-43338655	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.326T>A; p.L109H; 1:43338655-43338655	urinary_tract; bladder	carcinoma	Substitution - Missense
c.738C>G; p.L246L; 1:43340011-43340011	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.738C>G; p.L246L; 1:43340011-43340011	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.317C>T; p.P106L; 1:43338646-43338646	urinary_tract; bladder	carcinoma	Substitution - Missense

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COSMIC confirmed somatic mutation [Top]

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