Entrez Gene

Basic Information
Gene ID	4342
Name	MOS
Synonymous	v-mos Moloney murine sarcoma viral oncogene homolog;MOS;v-mos Moloney murine sarcoma viral oncogene homolog
Definition	c-mos\|oncogene MOS, Moloney murine sarcoma virus\|oocyte maturation factor mos\|proto-oncogene c-Mos\|proto-oncogene serine/threonine-protein kinase mos
Position	8q11
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.760G>C; p.E254Q; 8:56113223-56113223	breast	carcinoma	Substitution - Missense
c.262C>T; p.Q88*; 8:56113721-56113721	breast	carcinoma	Substitution - Nonsense
c.433G>C; p.V145L; 8:56113550-56113550	breast	carcinoma	Substitution - Missense
c.524T>C; p.L175S; 8:56113459-56113459	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.501C>T; p.C167C; 8:56113482-56113482	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.839C>T; p.S280L; 8:56113144-56113144	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.133C>T; p.R45W; 8:56113850-56113850	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.633G>T; p.E211D; 8:56113350-56113350	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.282G>T; p.K94N; 8:56113701-56113701	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.666C>T; p.C222C; 8:56113317-56113317	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.239G>A; p.R80H; 8:56113744-56113744	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.660C>T; p.F220F; 8:56113323-56113323	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.334C>T; p.L112L; 8:56113649-56113649	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.357C>T; p.R119R; 8:56113626-56113626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.224A>G; p.Y75C; 8:56113759-56113759	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.832C>T; p.P278S; 8:56113151-56113151	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.986C>A; p.P329Q; 8:56112997-56112997	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.986C>A; p.P329Q; 8:56112997-56112997	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.986C>A; p.P329Q; 8:56112997-56112997	large_intestine; colon	carcinoma	Substitution - Missense
c.986C>A; p.P329Q; 8:56112997-56112997	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.460G>A; p.A154T; 8:56113523-56113523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.901G>A; p.A301T; 8:56113082-56113082	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.935G>A; p.R312H; 8:56113048-56113048	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.974C>T; p.A325V; 8:56113009-56113009	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.974C>T; p.A325V; 8:56113009-56113009	large_intestine; colon	NS	Substitution - Missense
c.946G>A; p.V316I; 8:56113037-56113037	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.618C>T; p.N206N; 8:56113365-56113365	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1035C>T; p.L345L; 8:56112948-56112948	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.994C>T; p.R332W; 8:56112989-56112989	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.503G>A; p.R168H; 8:56113480-56113480	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.369C>T; p.A123A; 8:56113614-56113614	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.900C>T; p.S300S; 8:56113083-56113083	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.956G>A; p.R319H; 8:56113027-56113027	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.521G>C; p.S174T; 8:56113462-56113462	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>T; p.A277V; 8:56113153-56113153	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.84A>T; p.S28S; 8:56113899-56113899	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.209G>A; p.G70E; 8:56113774-56113774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.990C>T; p.S330S; 8:56112993-56112993	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.72C>A; p.C24*; 8:56113911-56113911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.339C>T; p.R113R; 8:56113644-56113644	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.613G>A; p.A205T; 8:56113370-56113370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.432C>T; p.N144N; 8:56113551-56113551	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.95C>T; p.A32V; 8:56113888-56113888	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.975G>A; p.A325A; 8:56113008-56113008	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.381G>A; p.T127T; 8:56113602-56113602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.833C>T; p.P278L; 8:56113150-56113150	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.325G>A; p.V109I; 8:56113658-56113658	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.325G>A; p.V109I; 8:56113658-56113658	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.660C>T; p.F220F; 8:56113323-56113323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.660C>T; p.F220F; 8:56113323-56113323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.660C>T; p.F220F; 8:56113323-56113323	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.245T>C; p.V82A; 8:56113738-56113738	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>A; p.A123T; 8:56113616-56113616	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.949A>G; p.I317V; 8:56113034-56113034	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.125G>A; p.R42Q; 8:56113858-56113858	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.286C>T; p.R96*; 8:56113697-56113697	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.483C>T; p.D161D; 8:56113500-56113500	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.837T>C; p.Y279Y; 8:56113146-56113146	liver	carcinoma	Substitution - coding silent
c.837T>C; p.Y279Y; 8:56113146-56113146	liver	carcinoma	Substitution - coding silent
c.21A>G; p.L7L; 8:56113962-56113962	liver	carcinoma	Substitution - coding silent
c.21A>G; p.L7L; 8:56113962-56113962	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.299G>A; p.R100Q; 8:56113684-56113684	liver	carcinoma	Substitution - Missense
c.302G>A; p.R101Q; 8:56113681-56113681	liver	carcinoma	Substitution - Missense
c.972C>T; p.S324S; 8:56113011-56113011	liver	carcinoma	Substitution - coding silent
c.972C>T; p.S324S; 8:56113011-56113011	liver	carcinoma	Substitution - coding silent
c.612C>A; p.P204P; 8:56113371-56113371	liver	carcinoma	Substitution - coding silent
c.553G>T; p.V185F; 8:56113430-56113430	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.63G>A; p.A21A; 8:56113920-56113920	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.744G>A; p.P248P; 8:56113239-56113239	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.928G>T; p.G310W; 8:56113055-56113055	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.228G>A; p.K76K; 8:56113755-56113755	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.336G>T; p.L112L; 8:56113647-56113647	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.776A>T; p.K259I; 8:56113207-56113207	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.670G>C; p.E224Q; 8:56113313-56113313	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.822C>T; p.T274T; 8:56113161-56113161	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.682G>C; p.D228H; 8:56113301-56113301	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.960C>A; p.C320*; 8:56113023-56113023	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.809G>C; p.W270S; 8:56113174-56113174	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.367G>A; p.A123T; 8:56113616-56113616	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.367G>A; p.A123T; 8:56113616-56113616	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.864C>G; p.Y288*; 8:56113119-56113119	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.409A>T; p.I137F; 8:56113574-56113574	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.995G>C; p.R332P; 8:56112988-56112988	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.779C>A; p.A260D; 8:56113204-56113204	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.503G>A; p.R168H; 8:56113480-56113480	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.88C>A; p.L30I; 8:56113895-56113895	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.62C>T; p.A21V; 8:56113921-56113921	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.206G>C; p.G69A; 8:56113777-56113777	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1041A>T; p.*347C; 8:56112942-56112942	ovary	carcinoma; serous_carcinoma	Nonstop extension
c.296C>A; p.S99Y; 8:56113687-56113687	pancreas	carcinoma	Substitution - Missense
c.296C>A; p.S99Y; 8:56113687-56113687	pancreas	carcinoma	Substitution - Missense
c.296C>A; p.S99Y; 8:56113687-56113687	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.955C>T; p.R319C; 8:56113028-56113028	pancreas	carcinoma	Substitution - Missense
c.583C>A; p.Q195K; 8:56113400-56113400	prostate	adenoma	Substitution - Missense
c.121C>T; p.P41S; 8:56113862-56113862	skin	malignant_melanoma	Substitution - Missense
c.96G>A; p.A32A; 8:56113887-56113887	skin	malignant_melanoma	Substitution - coding silent
c.757G>A; p.G253R; 8:56113226-56113226	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.80C>T; p.P27L; 8:56113903-56113903	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.983G>A; p.R328K; 8:56113000-56113000	skin	malignant_melanoma	Substitution - Missense
c.40G>A; p.E14K; 8:56113943-56113943	skin	malignant_melanoma	Substitution - Missense
c.581C>T; p.S194L; 8:56113402-56113402	skin; subungual	malignant_melanoma; acral_lentiginous	Substitution - Missense
c.660C>T; p.F220F; 8:56113323-56113323	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.47C>T; p.S16F; 8:56113936-56113936	skin	malignant_melanoma	Substitution - Missense
c.719G>A; p.G240E; 8:56113264-56113264	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1000C>T; p.L334F; 8:56112983-56112983	skin	malignant_melanoma	Substitution - Missense
c.427G>A; p.G143S; 8:56113556-56113556	skin	malignant_melanoma	Substitution - Missense
c.744G>T; p.P248P; 8:56113239-56113239	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.247C>T; p.P83S; 8:56113736-56113736	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.722G>A; p.G241D; 8:56113261-56113261	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.459C>T; p.G153G; 8:56113524-56113524	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.956G>A; p.R319H; 8:56113027-56113027	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.790T>C; p.S264P; 8:56113193-56113193	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.377G>A; p.R126H; 8:56113606-56113606	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>T; p.A277V; 8:56113153-56113153	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.356G>A; p.R119H; 8:56113627-56113627	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.95C>T; p.A32V; 8:56113888-56113888	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.921G>A; p.S307S; 8:56113062-56113062	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.375G>A; p.T125T; 8:56113608-56113608	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.375G>A; p.T125T; 8:56113608-56113608	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.986C>T; p.P329L; 8:56112997-56112997	stomach	adenocarcinoma	Substitution - Missense
c.891G>A; p.P297P; 8:56113092-56113092	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.125G>A; p.R42Q; 8:56113858-56113858	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.62C>T; p.A21V; 8:56113921-56113921	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.62C>T; p.A21V; 8:56113921-56113921	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.357C>T; p.R119R; 8:56113626-56113626	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.905C>T; p.A302V; 8:56113078-56113078	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.63G>A; p.A21A; 8:56113920-56113920	thyroid	carcinoma	Substitution - coding silent
c.618C>A; p.N206K; 8:56113365-56113365	urinary_tract; bladder	carcinoma	Substitution - Missense
c.901G>A; p.A301T; 8:56113082-56113082	urinary_tract; bladder	carcinoma	Substitution - Missense
c.96G>A; p.A32A; 8:56113887-56113887	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.96G>A; p.A32A; 8:56113887-56113887	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.54G>A; p.S18S; 8:56113929-56113929	urinary_tract; bladder	carcinoma	Substitution - coding silent

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COSMIC confirmed somatic mutation [Top]

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