Entrez Gene

Basic Information
Gene ID	4301
Name	MLLT4
Synonymous	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4;MLLT4;myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Definition	ALL1-fused gene from chromosome 6 protein\|afadin\|protein AF-6
Position	6q27
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.3416A>T; p.K1139M; 6:167946833-167946833	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.3461A>C; p.H1154P; 6:167946878-167946878	breast	carcinoma	Substitution - Missense
c.1021delC; p.Q341fs*2; 6:167890876-167890876	breast	carcinoma	Deletion - Frameshift
c.1844A>C; p.K615T; 6:167911344-167911344	breast	carcinoma	Substitution - Missense
c.4481G>A; p.S1494N; 6:167951904-167951904	breast	carcinoma	Substitution - Missense
c.2777G>T; p.C926F; 6:167918871-167918871	breast	carcinoma	Substitution - Missense
c.4001C>T; p.P1334L; 6:167951424-167951424	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.4656G>C; p.K1552N; 6:167952079-167952079	breast	carcinoma	Substitution - Missense
c.3326_3340del15; p.S1110_E1114delSEGFE; 6:167946743-167946757	breast	carcinoma	Deletion - In frame
c.1129A>C; p.T377P; 6:167890984-167890984	breast	carcinoma	Substitution - Missense
c.4151C>T; p.P1384L; 6:167951574-167951574	breast	carcinoma	Substitution - Missense
c.1216C>T; p.Q406*; 6:167896919-167896919	breast	carcinoma	Substitution - Nonsense
c.2896G>C; p.E966Q; 6:167922912-167922912	breast	carcinoma	Substitution - Missense
c.2512_2513insA; p.T838fs*4; 6:167917104-167917105	breast	carcinoma; ductal_carcinoma	Insertion - Frameshift
c.4640A>G; p.E1547G; 6:167952063-167952063	breast	carcinoma	Substitution - Missense
c.1897C>T; p.Q633*; 6:167911397-167911397	breast	carcinoma	Substitution - Nonsense
c.3536C>T; p.A1179V; 6:167947904-167947904	breast	carcinoma	Substitution - Missense
c.974T>G; p.L325*; 6:167889294-167889294	breast	carcinoma	Substitution - Nonsense
c.1902C>G; p.Y634*; 6:167911402-167911402	breast	carcinoma	Substitution - Nonsense
c.1643C>G; p.S548C; 6:167907211-167907211	breast	carcinoma	Substitution - Missense
c.3559G>A; p.G1187R; 6:167947927-167947927	breast	carcinoma	Substitution - Missense
c.3584C>T; p.T1195M; 6:167948300-167948300	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1746G>A; p.E582E; 6:167911125-167911125	central_nervous_system; brain	glioma	Substitution - coding silent
c.4090G>A; p.D1364N; 6:167951513-167951513	central_nervous_system; brain	glioma	Substitution - Missense
c.3059A>G; p.Y1020C; 6:167943157-167943157	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1654G>A; p.E552K; 6:167907222-167907222	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2927G>T; p.R976L; 6:167922943-167922943	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3068C>A; p.S1023*; 6:167943166-167943166	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2920_2922delCTT; p.L975delL; 6:167922936-167922938	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.4725G>A; p.M1575I; 6:167952148-167952148	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4163T>C; p.V1388A; 6:167951586-167951586	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1827C>A; p.S609R; 6:167911327-167911327	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3057C>A; p.I1019I; 6:167943155-167943155	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1545G>T; p.E515D; 6:167902329-167902329	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.289C>T; p.H97Y; 6:167864734-167864734	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4288A>G; p.T1430A; 6:167951711-167951711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3320G>A; p.R1107Q; 6:167946737-167946737	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3301C>T; p.R1101C; 6:167946718-167946718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3818G>A; p.R1273Q; 6:167951241-167951241	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4285C>T; p.R1429C; 6:167951708-167951708	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.302-1G>T; p.?; 6:167870385-167870385	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3417G>T; p.K1139N; 6:167946834-167946834	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.342A>G; p.Q114Q; 6:167870426-167870426	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4548C>T; p.I1516I; 6:167951971-167951971	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1503G>C; p.L501L; 6:167898438-167898438	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1309A>G; p.T437A; 6:167898244-167898244	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.933G>A; p.K311K; 6:167889253-167889253	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1880G>A; p.R627Q; 6:167911380-167911380	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2547T>C; p.N849N; 6:167917139-167917139	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1848G>A; p.L616L; 6:167911348-167911348	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3539A>G; p.K1180R; 6:167947907-167947907	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.618G>A; p.P206P; 6:167875377-167875377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4311G>A; p.P1437P; 6:167951734-167951734	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3143G>A; p.R1048Q; 6:167943448-167943448	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.604T>G; p.Y202D; 6:167875363-167875363	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.301+1G>A; p.?; 6:167864747-167864747	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.251G>A; p.R84Q; 6:167864696-167864696	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4471_4472insCC; p.G1492fs*30; 6:167951894-167951895	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Insertion - Frameshift
c.895-8T>C; p.?; 6:167889207-167889207	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.529C>T; p.R177*; 6:167872331-167872331	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Nonsense
c.2544A>C; p.P848P; 6:167917136-167917136	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2544A>C; p.P848P; 6:167917136-167917136	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.4202G>A; p.R1401H; 6:167951625-167951625	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2361G>C; p.V787V; 6:167915298-167915298	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.3069G>T; p.S1023S; 6:167943167-167943167	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.228G>A; p.A76A; 6:167864673-167864673	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.4806T>A; p.P1602P; 6:167952229-167952229	kidney	carcinoma; renal_cell_carcinoma	Substitution - coding silent
c.3446A>C; p.K1149T; 6:167946863-167946863	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.333A>G; p.L111L; 6:167870417-167870417	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1252G>T; p.D418Y; 6:167896955-167896955	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3107T>A; p.L1036Q; 6:167943412-167943412	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3328A>T; p.S1110C; 6:167946745-167946745	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3713A>T; p.E1238V; 6:167948429-167948429	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1681A>G; p.R561G; 6:167907249-167907249	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2747C>T; p.P916L; 6:167918841-167918841	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.531A>T; p.R177R; 6:167872333-167872333	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.4419G>T; p.T1473T; 6:167951842-167951842	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1216C>T; p.Q406*; 6:167896919-167896919	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2465C>T; p.A822V; 6:167915402-167915402	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2526T>G; p.Y842*; 6:167917118-167917118	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.3197G>T; p.S1066I; 6:167943967-167943967	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.895-2A>T; p.?; 6:167889213-167889213	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.895-2A>T; p.?; 6:167889213-167889213	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.3697T>G; p.W1233G; 6:167948413-167948413	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.959A>G; p.D320G; 6:167889279-167889279	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3097-2A>G; p.?; 6:167943400-167943400	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.2987T>C; p.L996P; 6:167925048-167925048	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2883G>C; p.W961C; 6:167922899-167922899	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.507G>T; p.K169N; 6:167872309-167872309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2988delA; p.K998fs*20; 6:167925049-167925049	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4753C>T; p.R1585*; 6:167952176-167952176	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3713delA; p.K1239fs*38; 6:167948429-167948429	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4030A>G; p.I1344V; 6:167951453-167951453	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1736C>A; p.S579Y; 6:167911115-167911115	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2926C>T; p.R976C; 6:167922942-167922942	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1928G>A; p.R643H; 6:167911428-167911428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3823C>T; p.R1275*; 6:167951246-167951246	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3823C>T; p.R1275*; 6:167951246-167951246	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3823C>T; p.R1275*; 6:167951246-167951246	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.217G>A; p.E73K; 6:167864662-167864662	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.753T>G; p.I251M; 6:167880376-167880376	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.727C>T; p.P243S; 6:167875486-167875486	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.806C>T; p.T269I; 6:167880429-167880429	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4496C>T; p.P1499L; 6:167951919-167951919	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1365C>T; p.Y455Y; 6:167898300-167898300	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1365C>T; p.Y455Y; 6:167898300-167898300	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.462G>C; p.Q154H; 6:167872264-167872264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4473G>A; p.S1491S; 6:167951896-167951896	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.181C>T; p.R61W; 6:167864626-167864626	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2860_2861delCA; p.R956fs*10; 6:167922876-167922877	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2860_2861delCA; p.R956fs*10; 6:167922876-167922877	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4075T>C; p.Y1359H; 6:167951498-167951498	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2236G>A; p.V746M; 6:167915173-167915173	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1426delG; p.A477fs*25; 6:167898361-167898361	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4579C>A; p.L1527I; 6:167952002-167952002	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4070T>C; p.V1357A; 6:167951493-167951493	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3170G>T; p.R1057M; 6:167943475-167943475	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4414C>T; p.R1472C; 6:167951837-167951837	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4344C>T; p.P1448P; 6:167951767-167951767	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3790C>T; p.R1264*; 6:167951213-167951213	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2385C>T; p.C795C; 6:167915322-167915322	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.136T>A; p.Y46N; 6:167864581-167864581	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.136T>A; p.Y46N; 6:167864581-167864581	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.131G>T; p.R44I; 6:167864576-167864576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.131G>T; p.R44I; 6:167864576-167864576	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2229A>G; p.I743M; 6:167914737-167914737	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4426C>T; p.R1476C; 6:167951849-167951849	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1919C>A; p.P640H; 6:167911419-167911419	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1071C>A; p.H357Q; 6:167890926-167890926	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.798G>T; p.L266L; 6:167880421-167880421	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.4477G>T; p.D1493Y; 6:167951900-167951900	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4202G>A; p.R1401H; 6:167951625-167951625	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2310C>A; p.L770L; 6:167915247-167915247	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.635G>A; p.R212Q; 6:167875394-167875394	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4693G>A; p.E1565K; 6:167952116-167952116	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3123G>A; p.Q1041Q; 6:167943428-167943428	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4589A>G; p.K1530R; 6:167952012-167952012	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.520G>T; p.E174*; 6:167872322-167872322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1010T>G; p.I337S; 6:167890865-167890865	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.250C>T; p.R84*; 6:167864695-167864695	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.250C>T; p.R84*; 6:167864695-167864695	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2287A>G; p.N763D; 6:167915224-167915224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1378C>T; p.R460C; 6:167898313-167898313	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3772C>T; p.R1258C; 6:167951195-167951195	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1585G>T; p.A529S; 6:167902369-167902369	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.385_387delAAG; p.K129delK; 6:167870469-167870471	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.2178G>A; p.M726I; 6:167914686-167914686	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2695C>T; p.R899C; 6:167918789-167918789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4095A>G; p.G1365G; 6:167951518-167951518	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.231G>T; p.E77D; 6:167864676-167864676	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3103C>T; p.R1035C; 6:167943408-167943408	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4054delC; p.P1353fs*29; 6:167951477-167951477	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4050G>A; p.P1350P; 6:167951473-167951473	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1941C>A; p.V647V; 6:167911441-167911441	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2147A>T; p.H716L; 6:167914655-167914655	liver	carcinoma	Substitution - Missense
c.2147A>T; p.H716L; 6:167914655-167914655	liver	carcinoma	Substitution - Missense
c.3615C>T; p.I1205I; 6:167948331-167948331	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.3060T>C; p.Y1020Y; 6:167943158-167943158	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.3060T>C; p.Y1020Y; 6:167943158-167943158	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.2496+5T>G; p.?; 6:167915438-167915438	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.2496+5T>G; p.?; 6:167915438-167915438	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.2283A>G; p.R761R; 6:167915220-167915220	liver	carcinoma	Substitution - coding silent
c.3790C>T; p.R1264*; 6:167951213-167951213	liver	carcinoma	Substitution - Nonsense
c.2416C>T; p.Q806*; 6:167915353-167915353	liver	carcinoma	Substitution - Nonsense
c.827C>A; p.A276D; 6:167880450-167880450	liver	carcinoma	Substitution - Missense
c.720T>A; p.D240E; 6:167875479-167875479	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2544A>C; p.P848P; 6:167917136-167917136	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1499G>T; p.G500V; 6:167898434-167898434	liver	carcinoma	Substitution - Missense
c.2361G>C; p.V787V; 6:167915298-167915298	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.3106C>T; p.L1036L; 6:167943411-167943411	liver	carcinoma	Substitution - coding silent
c.4544A>G; p.H1515R; 6:167951967-167951967	liver	carcinoma	Substitution - Missense
c.4544A>G; p.H1515R; 6:167951967-167951967	liver	carcinoma	Substitution - Missense
c.1471G>A; p.A491T; 6:167898406-167898406	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2355A>G; p.R785R; 6:167915292-167915292	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4152G>T; p.P1384P; 6:167951575-167951575	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4202_4203insT; p.W1402fs*3; 6:167951625-167951626	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.4483C>T; p.L1495L; 6:167951906-167951906	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2109A>T; p.L703F; 6:167914287-167914287	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1951G>A; p.V651I; 6:167911451-167911451	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4003G>T; p.A1335S; 6:167951426-167951426	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1807A>G; p.I603V; 6:167911307-167911307	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3301C>T; p.R1101C; 6:167946718-167946718	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3697T>C; p.W1233R; 6:167948413-167948413	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.592G>T; p.A198S; 6:167875351-167875351	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.129G>T; p.M43I; 6:167864574-167864574	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.431C>A; p.P144H; 6:167872233-167872233	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.3175G>A; p.A1059T; 6:167943945-167943945	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3763C>T; p.R1255C; 6:167951186-167951186	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1035G>A; p.R345R; 6:167890890-167890890	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3437G>C; p.R1146T; 6:167946854-167946854	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4602C>G; p.S1534R; 6:167952025-167952025	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4592C>T; p.P1531L; 6:167952015-167952015	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2634C>T; p.I878I; 6:167917226-167917226	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3878G>T; p.S1293I; 6:167951301-167951301	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2571A>G; p.L857L; 6:167917163-167917163	lung	carcinoma; undifferentiated_carcinoma	Substitution - coding silent
c.3847A>C; p.K1283Q; 6:167951270-167951270	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.239G>A; p.R80Q; 6:167864684-167864684	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3874C>G; p.Q1292E; 6:167951297-167951297	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.615G>T; p.M205I; 6:167875374-167875374	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.4072C>A; p.H1358N; 6:167951495-167951495	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.893G>A; p.R298Q; 6:167880516-167880516	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4596C>T; p.D1532D; 6:167952019-167952019	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1240A>G; p.T414A; 6:167896943-167896943	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.728C>T; p.P243L; 6:167875487-167875487	NS	malignant_melanoma	Substitution - Missense
c.889G>A; p.A297T; 6:167880512-167880512	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.737-10_737-9insT; p.?; 6:167880350-167880351	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.1092G>A; p.K364K; 6:167890947-167890947	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.4456_4457delAA; p.K1486fs*78; 6:167951879-167951880	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1530_1531insG; p.I512fs*8; 6:167898465-167898466	ovary	carcinoma; serous_carcinoma	Insertion - Frameshift
c.4030A>G; p.I1344V; 6:167951453-167951453	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2866C>T; p.R956C; 6:167922882-167922882	ovary	other; neoplasm	Substitution - Missense
c.4255A>T; p.R1419*; 6:167951678-167951678	ovary	carcinoma; serous_carcinoma	Substitution - Nonsense
c.3097-3T>G; p.?; 6:167943399-167943399	ovary	other; neoplasm	Unknown
c.893G>T; p.R298L; 6:167880516-167880516	pancreas	carcinoma	Substitution - Missense
c.893G>T; p.R298L; 6:167880516-167880516	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.2416C>T; p.Q806*; 6:167915353-167915353	pancreas	carcinoma	Substitution - Nonsense
c.4312T>C; p.F1438L; 6:167951735-167951735	pancreas	carcinoma	Substitution - Missense
c.1941C>T; p.V647V; 6:167911441-167911441	pancreas	carcinoma	Substitution - coding silent
c.1941C>T; p.V647V; 6:167911441-167911441	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1269+1G>T; p.?; 6:167896973-167896973	prostate	carcinoma; adenocarcinoma	Unknown
c.3068C>T; p.S1023L; 6:167943166-167943166	prostate	carcinoma	Substitution - Missense
c.365G>T; p.R122L; 6:167870449-167870449	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2675_2676insC; p.T893fs*4; 6:167918769-167918770	salivary_gland; tongue	carcinoma; adenoid_cystic_carcinoma	Insertion - Frameshift
c.343C>T; p.L115L; 6:167870427-167870427	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4509C>T; p.D1503D; 6:167951932-167951932	skin	malignant_melanoma	Substitution - coding silent
c.208G>A; p.D70N; 6:167864653-167864653	skin	malignant_melanoma	Substitution - Missense
c.2833C>T; p.Q945*; 6:167918927-167918927	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2962G>A; p.E988K; 6:167925023-167925023	skin	malignant_melanoma	Substitution - Missense
c.2641G>A; p.D881N; 6:167918735-167918735	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1836C>T; p.V612V; 6:167911336-167911336	skin	malignant_melanoma	Substitution - coding silent
c.4663C>T; p.Q1555*; 6:167952086-167952086	skin	malignant_melanoma	Substitution - Nonsense
c.2644C>T; p.L882F; 6:167918738-167918738	skin	malignant_melanoma	Substitution - Missense
c.2627C>T; p.P876L; 6:167917219-167917219	skin; scalp	malignant_melanoma	Substitution - Missense
c.4472C>T; p.S1491L; 6:167951895-167951895	skin	malignant_melanoma	Substitution - Missense
c.880T>C; p.Y294H; 6:167880503-167880503	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3522C>T; p.A1174A; 6:167947890-167947890	skin	malignant_melanoma	Substitution - coding silent
c.907C>T; p.P303S; 6:167889227-167889227	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1251G>A; p.L417L; 6:167896954-167896954	skin	malignant_melanoma	Substitution - coding silent
c.4591_4592CC>TT; p.P1531L; 6:167952014-167952015	skin; mucosal	malignant_melanoma	Substitution - Missense
c.331C>G; p.L111V; 6:167870415-167870415	skin	malignant_melanoma	Substitution - Missense
c.478C>T; p.L160F; 6:167872280-167872280	skin	malignant_melanoma	Substitution - Missense
c.468C>T; p.F156F; 6:167872270-167872270	skin	malignant_melanoma	Substitution - coding silent
c.904C>T; p.P302S; 6:167889224-167889224	skin	malignant_melanoma	Substitution - Missense
c.4803_4804CC>TT; p.P1602S; 6:167952226-167952227	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.921T>A; p.H307Q; 6:167889241-167889241	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.140T>G; p.F47C; 6:167864585-167864585	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3484A>G; p.N1162D; 6:167946901-167946901	skin	malignant_melanoma	Substitution - Missense
c.238C>T; p.R80*; 6:167864683-167864683	skin	malignant_melanoma	Substitution - Nonsense
c.238C>T; p.R80*; 6:167864683-167864683	skin	malignant_melanoma	Substitution - Nonsense
c.4512C>T; p.A1504A; 6:167951935-167951935	skin	malignant_melanoma	Substitution - coding silent
c.2634C>T; p.I878I; 6:167917226-167917226	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.851A>T; p.Y284F; 6:167880474-167880474	skin	malignant_melanoma	Substitution - Missense
c.4573C>T; p.Q1525*; 6:167951996-167951996	skin; trunk	malignant_melanoma	Substitution - Nonsense
c.4352C>T; p.P1451L; 6:167951775-167951775	skin	malignant_melanoma	Substitution - Missense
c.4291C>T; p.Q1431*; 6:167951714-167951714	skin	malignant_melanoma	Substitution - Nonsense
c.3143G>A; p.R1048Q; 6:167943448-167943448	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4032C>T; p.I1344I; 6:167951455-167951455	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3776C>T; p.S1259F; 6:167951199-167951199	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.694A>T; p.R232*; 6:167875453-167875453	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.2891A>G; p.Y964C; 6:167922907-167922907	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3615C>T; p.I1205I; 6:167948331-167948331	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3764G>A; p.R1255H; 6:167951187-167951187	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1891T>C; p.S631P; 6:167911391-167911391	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.993G>A; p.W331*; 6:167889313-167889313	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.283G>C; p.E95Q; 6:167864728-167864728	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4738C>T; p.R1580C; 6:167952161-167952161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3685C>T; p.P1229S; 6:167948401-167948401	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.257T>A; p.L86Q; 6:167864702-167864702	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3425C>A; p.P1142H; 6:167946842-167946842	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.827C>A; p.A276D; 6:167880450-167880450	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.529C>T; p.R177*; 6:167872331-167872331	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1445A>C; p.K482T; 6:167898380-167898380	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1270-10C>T; p.?; 6:167898195-167898195	stomach	carcinoma; adenocarcinoma	Unknown
c.4223C>T; p.A1408V; 6:167951646-167951646	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.815C>A; p.P272H; 6:167880438-167880438	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3024A>G; p.A1008A; 6:167925085-167925085	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2275C>T; p.R759C; 6:167915212-167915212	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2695C>T; p.R899C; 6:167918789-167918789	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.365G>A; p.R122Q; 6:167870449-167870449	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3596G>A; p.R1199K; 6:167948312-167948312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3103C>T; p.R1035C; 6:167943408-167943408	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4320C>T; p.P1440P; 6:167951743-167951743	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.4625G>A; p.R1542H; 6:167952048-167952048	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4291C>G; p.Q1431E; 6:167951714-167951714	thyroid	carcinoma	Substitution - Missense
c.2457G>T; p.L819L; 6:167915394-167915394	thyroid	other; neoplasm	Substitution - coding silent
c.478C>G; p.L160V; 6:167872280-167872280	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4248G>A; p.R1416R; 6:167951671-167951671	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1335G>A; p.V445V; 6:167898270-167898270	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3714A>C; p.E1238D; 6:167948430-167948430	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3714A>C; p.E1238D; 6:167948430-167948430	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.4483C>T; p.L1495L; 6:167951906-167951906	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.296G>A; p.S99N; 6:167864741-167864741	urinary_tract; bladder	carcinoma	Substitution - Missense
c.482C>G; p.S161*; 6:167872284-167872284	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.3191G>C; p.R1064T; 6:167943961-167943961	urinary_tract; bladder	carcinoma	Substitution - Missense

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COSMIC confirmed somatic mutation [Top]

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