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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3945

Name

LDHB

Synonymous

lactate dehydrogenase B;LDHB;lactate dehydrogenase B

Definition

L-lactate dehydrogenase B chain|LDH heart subunit|epididymis secretory protein Li 281|lactate dehydrogenase H chain|renal carcinoma antigen NY-REN-46

Position

12p12.2-p12.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.557G>T; p.C186F; 12:21641990-21641990

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.376G>A; p.V126I; 12:21643980-21643980

 bone; fibulaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.766A>C; p.S256R; 12:21637142-21637142

 bone; sternumchondrosarcomaSubstitution - Missense

c.129+1G>T; p.?; 12:21654542-21654542

 breastcarcinoma; ductal_carcinomaUnknown

c.129+1G>T; p.?; 12:21654542-21654542

 breastcarcinoma; ductal_carcinomaUnknown

c.262G>A; p.A88T; 12:21644094-21644094

 central_nervous_system; braingliomaSubstitution - Missense

c.726C>T; p.V242V; 12:21637182-21637182

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.64A>T; p.N22Y; 12:21654608-21654608

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.278T>C; p.V93A; 12:21644078-21644078

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.266A>G; p.N89S; 12:21644090-21644090

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.4G>A; p.A2T; 12:21654668-21654668

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.754G>A; p.A252T; 12:21637154-21637154

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.943G>A; p.A315T; 12:21635604-21635604

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.686A>T; p.K229M; 12:21638380-21638380

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.42A>G; p.E14E; 12:21654630-21654630

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.380A>G; p.K127R; 12:21643976-21643976

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.728T>C; p.I243T; 12:21637180-21637180

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.182G>A; p.G61E; 12:21646964-21646964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.699G>T; p.K233N; 12:21638367-21638367

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.473G>A; p.R158H; 12:21642074-21642074

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1005A>C; p.*335C; 12:21635542-21635542

 large_intestine; coloncarcinoma; adenocarcinomaNonstop extension

c.86T>C; p.V29A; 12:21654586-21654586

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.503C>A; p.S168Y; 12:21642044-21642044

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.292G>T; p.G98*; 12:21644064-21644064

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.832G>T; p.V278L; 12:21637076-21637076

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.104C>T; p.A35V; 12:21654568-21654568

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.584G>A; p.G195D; 12:21641963-21641963

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.89G>A; p.G30E; 12:21654583-21654583

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.379A>G; p.K127E; 12:21643977-21643977

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.439G>A; p.V147I; 12:21642108-21642108

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.184G>T; p.E62*; 12:21646962-21646962

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.298C>T; p.R100C; 12:21644058-21644058

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.655A>G; p.M219V; 12:21638411-21638411

 livercarcinomaSubstitution - Missense

c.868C>T; p.L290L; 12:21635679-21635679

 livercarcinomaSubstitution - coding silent

c.757A>G; p.I253V; 12:21637151-21637151

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.103G>T; p.A35S; 12:21654569-21654569

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.530A>T; p.E177V; 12:21642017-21642017

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.421+2T>C; p.?; 12:21643933-21643933

 lungcarcinoma; small_cell_carcinomaUnknown

c.899G>T; p.G300V; 12:21635648-21635648

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.840G>T; p.G280G; 12:21635707-21635707

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.982C>T; p.Q328*; 12:21635565-21635565

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.953A>G; p.K318R; 12:21635594-21635594

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.867C>T; p.F289F; 12:21635680-21635680

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.820G>T; p.V274L; 12:21637088-21637088

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.320G>C; p.R107P; 12:21644036-21644036

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.501T>C; p.D167D; 12:21642046-21642046

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.289G>C; p.A97P; 12:21644067-21644067

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.548C>T; p.P183L; 12:21641999-21641999

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.972G>A; p.L324L; 12:21635575-21635575

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.172A>G; p.K58E; 12:21646974-21646974

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.837+4A>C; p.?; 12:21637067-21637067

 oesophagus; lower_thirdcarcinoma; adenocarcinomaUnknown

c.381G>C; p.K127N; 12:21643975-21643975

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.997G>T; p.D333Y; 12:21635550-21635550

 pancreascarcinomaSubstitution - Missense

c.997G>T; p.D333Y; 12:21635550-21635550

 pancreascarcinomaSubstitution - Missense

c.997G>T; p.D333Y; 12:21635550-21635550

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.39G>A; p.A13A; 12:21654633-21654633

 pancreascarcinomaSubstitution - coding silent

c.376G>A; p.V126I; 12:21643980-21643980

 prostatecarcinomaSubstitution - Missense

c.66T>C; p.N22N; 12:21654606-21654606

 skinmalignant_melanomaSubstitution - coding silent

c.254C>T; p.S85F; 12:21644102-21644102

 skinmalignant_melanomaSubstitution - Missense

c.817C>A; p.P273T; 12:21637091-21637091

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.68A>G; p.K23R; 12:21654604-21654604

 skinmalignant_melanomaSubstitution - Missense

c.878C>T; p.P293L; 12:21635669-21635669

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.389C>T; p.P130L; 12:21643967-21643967

 skin; trunkmalignant_melanomaSubstitution - Missense

c.481G>A; p.G161R; 12:21642066-21642066

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.374T>G; p.I125S; 12:21643982-21643982

 skinmalignant_melanomaSubstitution - Missense

c.10C>T; p.L4F; 12:21654662-21654662

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.895C>T; p.R299W; 12:21635652-21635652

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.99T>A; p.G33G; 12:21654573-21654573

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.49G>A; p.A17T; 12:21654623-21654623

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.890A>G; p.N297S; 12:21635657-21635657

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.79G>A; p.V27M; 12:21654593-21654593

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.818C>T; p.P273L; 12:21637090-21637090

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.627T>G; p.G209G; 12:21638439-21638439

 thyroidother; neoplasmSubstitution - coding silent

c.837G>A; p.K279K; 12:21637071-21637071

 thyroidother; neoplasmSubstitution - coding silent

c.890A>G; p.N297S; 12:21635657-21635657

 urinary_tract; bladdercarcinomaSubstitution - Missense