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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3725

Name

JUN

Synonymous

jun proto-oncogene;JUN;jun proto-oncogene

Definition

Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog

Position

1p32-p31

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.877G>C; p.E293Q; 1:58782194-58782194

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.434_435insC; p.A146fs*164; 1:58782636-58782637

 biliary_tract; bile_ductcarcinoma; adenocarcinomaInsertion - Frameshift

c.334G>A; p.E112K; 1:58782737-58782737

 breastcarcinomaSubstitution - Missense

c.245delA; p.Q82fs*22; 1:58782826-58782826

 breastcarcinomaDeletion - Frameshift

c.358G>T; p.E120*; 1:58782713-58782713

 breastcarcinomaSubstitution - Nonsense

c.297C>A; p.C99*; 1:58782774-58782774

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Nonsense

c.351C>T; p.A117A; 1:58782720-58782720

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.849A>C; p.K283N; 1:58782222-58782222

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.667C>G; p.Q223E; 1:58782404-58782404

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.38C>A; p.A13D; 1:58783033-58783033

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.834C>G; p.A278A; 1:58782237-58782237

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.885G>A; p.A295A; 1:58782186-58782186

 kidneyother; neoplasmSubstitution - coding silent

c.769_770insA; p.R257fs*53; 1:58782301-58782302

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.362T>C; p.L121P; 1:58782709-58782709

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.788G>A; p.R263H; 1:58782283-58782283

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.198_199insT; p.G67fs*40; 1:58782872-58782873

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.930_931delGA; p.K311fs*6; 1:58782140-58782141

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.776G>A; p.R259H; 1:58782295-58782295

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.283delA; p.T95fs*9; 1:58782788-58782788

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.917C>T; p.A306V; 1:58782154-58782154

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.750G>A; p.Q250Q; 1:58782321-58782321

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.890C>T; p.T297M; 1:58782181-58782181

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.612G>A; p.Q204Q; 1:58782459-58782459

 livercarcinomaSubstitution - coding silent

c.612G>A; p.Q204Q; 1:58782459-58782459

 livercarcinomaSubstitution - coding silent

c.256G>T; p.G86W; 1:58782815-58782815

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.334G>C; p.E112Q; 1:58782737-58782737

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.273G>T; p.T91T; 1:58782798-58782798

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.322G>C; p.E108Q; 1:58782749-58782749

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.792C>G; p.I264M; 1:58782279-58782279

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.334G>A; p.E112K; 1:58782737-58782737

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.48C>T; p.A16A; 1:58783023-58783023

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.204G>T; p.L68L; 1:58782867-58782867

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.243C>G; p.I81M; 1:58782828-58782828

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.94A>G; p.K32E; 1:58782977-58782977

 NSmalignant_melanomaSubstitution - Missense

c.94A>G; p.K32E; 1:58782977-58782977

 NSmalignant_melanomaSubstitution - Missense

c.334G>A; p.E112K; 1:58782737-58782737

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.472G>A; p.G158S; 1:58782599-58782599

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.174G>T; p.S58S; 1:58782897-58782897

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.460A>T; p.S154C; 1:58782611-58782611

 skin; trunkmalignant_melanomaSubstitution - Missense

c.110G>T; p.S37I; 1:58782961-58782961

 skinmalignant_melanomaSubstitution - Missense

c.593C>T; p.P198L; 1:58782478-58782478

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.23_24CC>TT; p.T8I; 1:58783047-58783048

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.145C>T; p.L49L; 1:58782926-58782926

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.159C>T; p.L53L; 1:58782912-58782912

 skinmalignant_melanomaSubstitution - coding silent

c.159C>T; p.L53L; 1:58782912-58782912

 skinmalignant_melanomaSubstitution - coding silent

c.642G>A; p.Q214Q; 1:58782429-58782429

 skinmalignant_melanomaSubstitution - coding silent

c.54C>T; p.F18F; 1:58783017-58783017

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.401C>A; p.A134E; 1:58782670-58782670

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.118C>A; p.L40M; 1:58782953-58782953

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.920A>G; p.Q307R; 1:58782151-58782151

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.50C>T; p.S17L; 1:58783021-58783021

 thyroidcarcinomaSubstitution - Missense

c.543G>A; p.L181L; 1:58782528-58782528

 urinary_tract; bladdercarcinomaSubstitution - coding silent