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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3675

Name

ITGA3

Synonymous

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor);ITGA3;integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

Definition

CD49 antigen-like family member C|FRP-2|VLA-3 subunit alpha|antigen identified by monoclonal antibody J143|galactoprotein B3|integrin alpha-3|very late activation protein 3 receptor, alpha-3 subunit

Position

17q21.33

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.983C>T; p.A328V; 17:50072009-50072009

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.982G>A; p.A328T; 17:50072008-50072008

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.2574C>G; p.L858L; 17:50079249-50079249

 breastcarcinomaSubstitution - coding silent

c.3095A>G; p.H1032R; 17:50089159-50089159

 breastcarcinomaSubstitution - Missense

c.957T>C; p.D319D; 17:50071516-50071516

 breastcarcinomaSubstitution - coding silent

c.2442G>T; p.L814L; 17:50079117-50079117

 breastcarcinomaSubstitution - coding silent

c.2817C>T; p.I939I; 17:50080372-50080372

 central_nervous_system; braingliomaSubstitution - coding silent

c.2327G>A; p.G776E; 17:50078853-50078853

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.496G>A; p.G166S; 17:50068137-50068137

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1794C>T; p.N598N; 17:50076445-50076445

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1483C>A; p.L495M; 17:50075472-50075472

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2263C>T; p.L755L; 17:50078250-50078250

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1026C>A; p.I342I; 17:50072052-50072052

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.3068G>A; p.R1023H; 17:50089132-50089132

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.722A>G; p.D241G; 17:50070901-50070901

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.3185G>A; p.R1062Q; 17:50089249-50089249

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.584G>T; p.G195V; 17:50068225-50068225

 endometriumcarcinoma; serous_carcinomaSubstitution - Missense

c.636C>T; p.F212F; 17:50068277-50068277

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2154C>T; p.I718I; 17:50078060-50078060

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.3062G>A; p.R1021Q; 17:50089126-50089126

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1186T>G; p.L396V; 17:50073945-50073945

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.996C>T; p.F332F; 17:50072022-50072022

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.1230T>C; p.L410L; 17:50073989-50073989

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.2155G>A; p.A719T; 17:50078061-50078061

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1707C>G; p.I569M; 17:50076358-50076358

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.833T>C; p.M278T; 17:50071392-50071392

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.710A>G; p.Y237C; 17:50070889-50070889

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.695G>T; p.W232L; 17:50070874-50070874

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2118C>G; p.N706K; 17:50077426-50077426

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2839C>T; p.R947*; 17:50081328-50081328

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2922C>A; p.F974L; 17:50087746-50087746

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.78C>T; p.G26G; 17:50056517-50056517

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.206+1G>A; p.?; 17:50056646-50056646

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.2205G>A; p.Q735Q; 17:50078111-50078111

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2205G>A; p.Q735Q; 17:50078111-50078111

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.2205G>A; p.Q735Q; 17:50078111-50078111

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.996C>T; p.F332F; 17:50072022-50072022

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2642G>C; p.G881A; 17:50079493-50079493

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.3019G>T; p.G1007W; 17:50087843-50087843

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.903G>A; p.S301S; 17:50071462-50071462

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.705T>A; p.S235S; 17:50070884-50070884

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1070C>A; p.P357H; 17:50072096-50072096

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2191G>A; p.D731N; 17:50078097-50078097

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2019G>A; p.A673A; 17:50077070-50077070

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.2206C>G; p.L736V; 17:50078112-50078112

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2310G>A; p.R770R; 17:50078836-50078836

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2209C>T; p.Q737*; 17:50078115-50078115

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2871C>T; p.F957F; 17:50081360-50081360

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2466C>T; p.Y822Y; 17:50079141-50079141

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1090C>T; p.P364S; 17:50072116-50072116

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2850A>T; p.V950V; 17:50081339-50081339

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.703T>C; p.S235P; 17:50070882-50070882

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.913G>A; p.A305T; 17:50071472-50071472

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1943T>C; p.V648A; 17:50076994-50076994

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2554C>G; p.L852V; 17:50079229-50079229

 large_intestine; colonNSSubstitution - Missense

c.1833C>T; p.F611F; 17:50076592-50076592

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1230T>C; p.L410L; 17:50073989-50073989

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2155G>A; p.A719T; 17:50078061-50078061

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1015delG; p.G340fs*7; 17:50072041-50072041

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.2332A>G; p.T778A; 17:50078858-50078858

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1982G>A; p.R661Q; 17:50077033-50077033

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.250T>C; p.Y84H; 17:50064120-50064120

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1393G>A; p.V465I; 17:50074458-50074458

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.705T>C; p.S235S; 17:50070884-50070884

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.839C>T; p.A280V; 17:50071398-50071398

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1022C>T; p.A341V; 17:50072048-50072048

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2351G>T; p.G784V; 17:50078877-50078877

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.221delC; p.R76fs*31; 17:50064091-50064091

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1765C>T; p.R589W; 17:50076416-50076416

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1252C>A; p.H418N; 17:50074150-50074150

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2074G>C; p.G692R; 17:50077382-50077382

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.467G>T; p.R156L; 17:50068108-50068108

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.686G>A; p.R229H; 17:50070865-50070865

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2560A>G; p.N854D; 17:50079235-50079235

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2839C>T; p.R947*; 17:50081328-50081328

 livercarcinomaSubstitution - Nonsense

c.3185G>A; p.R1062Q; 17:50089249-50089249

 livercarcinomaSubstitution - Missense

c.1645C>T; p.R549C; 17:50075706-50075706

 livercarcinomaSubstitution - Missense

c.1645C>T; p.R549C; 17:50075706-50075706

 livercarcinomaSubstitution - Missense

c.2297+4G>A; p.?; 17:50078288-50078288

 livercarcinomaUnknown

c.2429G>A; p.G810D; 17:50079104-50079104

 livercarcinomaSubstitution - Missense

c.1583G>T; p.R528L; 17:50075644-50075644

 livercarcinomaSubstitution - Missense

c.1583G>T; p.R528L; 17:50075644-50075644

 livercarcinomaSubstitution - Missense

c.2086G>T; p.A696S; 17:50077394-50077394

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.513G>T; p.L171L; 17:50068154-50068154

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1466C>T; p.S489F; 17:50074531-50074531

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.2876G>T; p.R959L; 17:50081365-50081365

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1842G>T; p.E614D; 17:50076601-50076601

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.582G>T; p.T194T; 17:50068223-50068223

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2136G>C; p.Q712H; 17:50077444-50077444

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1547A>G; p.Y516C; 17:50075608-50075608

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1748G>A; p.R583H; 17:50076399-50076399

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1197G>T; p.V399V; 17:50073956-50073956

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2436G>A; p.G812G; 17:50079111-50079111

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1777G>A; p.A593T; 17:50076428-50076428

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.475G>T; p.V159L; 17:50068116-50068116

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1742C>T; p.P581L; 17:50076393-50076393

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.690G>T; p.K230N; 17:50070869-50070869

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1617C>T; p.F539F; 17:50075678-50075678

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.3005G>T; p.G1002V; 17:50087829-50087829

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.466C>G; p.R156G; 17:50068107-50068107

 NSmalignant_melanomaSubstitution - Missense

c.1100C>G; p.S367C; 17:50072126-50072126

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.639C>T; p.G213G; 17:50068280-50068280

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.2615G>T; p.R872L; 17:50079466-50079466

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1207C>T; p.H403Y; 17:50073966-50073966

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1246G>A; p.V416I; 17:50074144-50074144

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1091C>G; p.P364R; 17:50072117-50072117

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.703T>C; p.S235P; 17:50070882-50070882

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1678A>C; p.N560H; 17:50076329-50076329

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.2179C>T; p.L727L; 17:50078085-50078085

 ovaryother; neoplasmSubstitution - coding silent

c.2179C>T; p.L727L; 17:50078085-50078085

 ovaryother; neoplasmSubstitution - coding silent

c.1389G>T; p.R463R; 17:50074454-50074454

 pancreasNSSubstitution - coding silent

c.1583G>A; p.R528Q; 17:50075644-50075644

 pituitary; craniopharyngeal_ductcraniopharyngioma; adamantinomatousSubstitution - Missense

c.1202T>A; p.I401N; 17:50073961-50073961

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1787T>G; p.I596S; 17:50076438-50076438

 prostatecarcinomaSubstitution - Missense

c.584G>T; p.G195V; 17:50068225-50068225

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.417C>T; p.V139V; 17:50068058-50068058

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1712C>T; p.S571F; 17:50076363-50076363

 skinmalignant_melanomaSubstitution - Missense

c.1596C>T; p.A532A; 17:50075657-50075657

 skinmalignant_melanomaSubstitution - coding silent

c.2177C>T; p.T726I; 17:50078083-50078083

 skinmalignant_melanomaSubstitution - Missense

c.711T>C; p.Y237Y; 17:50070890-50070890

 skinmalignant_melanomaSubstitution - coding silent

c.340C>A; p.P114T; 17:50064533-50064533

 skinmalignant_melanomaSubstitution - Missense

c.2928G>A; p.V976V; 17:50087752-50087752

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.2766C>T; p.P922P; 17:50080321-50080321

 skinmalignant_melanomaSubstitution - coding silent

c.2257A>T; p.T753S; 17:50078244-50078244

 skinmalignant_melanomaSubstitution - Missense

c.2836G>C; p.D946H; 17:50081325-50081325

 skin; legmalignant_melanomaSubstitution - Missense

c.1341C>T; p.D447D; 17:50074239-50074239

 skinmalignant_melanomaSubstitution - coding silent

c.226C>T; p.R76W; 17:50064096-50064096

 skinmalignant_melanomaSubstitution - Missense

c.126G>A; p.V42V; 17:50056565-50056565

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1174C>T; p.P392S; 17:50073933-50073933

 skinmalignant_melanomaSubstitution - Missense

c.2994C>T; p.A998A; 17:50087818-50087818

 skinmalignant_melanomaSubstitution - coding silent

c.1091C>T; p.P364L; 17:50072117-50072117

 skinmalignant_melanomaSubstitution - Missense

c.2372T>A; p.V791E; 17:50078898-50078898

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2398C>T; p.Q800*; 17:50078924-50078924

 skinmalignant_melanomaSubstitution - Nonsense

c.175C>T; p.H59Y; 17:50056614-50056614

 skinmalignant_melanomaSubstitution - Missense

c.1695C>T; p.L565L; 17:50076346-50076346

 skinmalignant_melanomaSubstitution - coding silent

c.1463C>T; p.T488I; 17:50074528-50074528

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1469+10T>C; p.?; 17:50074544-50074544

 stomachcarcinoma; adenocarcinomaUnknown

c.2916G>A; p.T972T; 17:50081405-50081405

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2285C>T; p.T762I; 17:50078272-50078272

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.837C>T; p.G279G; 17:50071396-50071396

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.493C>T; p.R165*; 17:50068134-50068134

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.2155G>A; p.A719T; 17:50078061-50078061

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.581C>T; p.T194M; 17:50068222-50068222

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2490G>A; p.L830L; 17:50079165-50079165

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.2074G>A; p.G692R; 17:50077382-50077382

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2074G>A; p.G692R; 17:50077382-50077382

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.2219+1G>A; p.?; 17:50078126-50078126

 stomachcarcinoma; adenocarcinomaUnknown

c.1035C>T; p.F345F; 17:50072061-50072061

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - coding silent

c.2774C>T; p.T925I; 17:50080329-50080329

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.858G>T; p.Q286H; 17:50071417-50071417

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1382G>A; p.R461Q; 17:50074280-50074280

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1230T>C; p.L410L; 17:50073989-50073989

 thyroidother; neoplasmSubstitution - coding silent

c.2621G>T; p.R874L; 17:50079472-50079472

 thyroidcarcinomaSubstitution - Missense

c.2368G>A; p.D790N; 17:50078894-50078894

 thyroidcarcinomaSubstitution - Missense

c.2055G>A; p.L685L; 17:50077106-50077106

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - coding silent

c.2055G>A; p.L685L; 17:50077106-50077106

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - coding silent

c.2046_2047insCTG; p.L685_S686insL; 17:50077097-50077098

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - In frame

c.1961G>C; p.S654T; 17:50077012-50077012

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1961G>C; p.S654T; 17:50077012-50077012

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.2223G>A; p.S741S; 17:50078210-50078210

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.2534C>A; p.P845H; 17:50079209-50079209

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.2140-1G>A; p.?; 17:50078045-50078045

 urinary_tract; bladdercarcinomaUnknown

c.2472C>T; p.V824V; 17:50079147-50079147

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.2472C>T; p.V824V; 17:50079147-50079147

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1066C>T; p.H356Y; 17:50072092-50072092

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.187G>A; p.E63K; 17:50056626-50056626

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1791C>T; p.L597L; 17:50076442-50076442

 urinary_tract; bladdercarcinomaSubstitution - coding silent