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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3660

Name

IRF2

Synonymous

interferon regulatory factor 2;IRF2;interferon regulatory factor 2

Definition

-

Position

4q34.1-q35.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.678C>T; p.P226P; 4:184398931-184398931

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.989C>T; p.T330I; 4:184388819-184388819

 breastcarcinomaSubstitution - Missense

c.746G>A; p.R249Q; 4:184389062-184389062

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.249C>T; p.C83C; 4:184418647-184418647

 central_nervous_system; braingliomaSubstitution - coding silent

c.88-5_88-4delTT; p.?; 4:184419572-184419573

 central_nervous_system; brainglioma; astrocytoma_Grade_IIIUnknown

c.128G>C; p.R43T; 4:184419528-184419528

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.538C>T; p.Q180*; 4:184399071-184399071

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.476C>T; p.A159V; 4:184408211-184408211

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.639G>A; p.P213P; 4:184398970-184398970

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.236C>T; p.A79V; 4:184418660-184418660

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1012A>G; p.T338A; 4:184388796-184388796

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.108C>T; p.I36I; 4:184419548-184419548

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.683C>T; p.S228F; 4:184398926-184398926

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.249C>T; p.C83C; 4:184418647-184418647

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.327C>T; p.Y109Y; 4:184418569-184418569

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.250G>C; p.A84P; 4:184418646-184418646

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.702_706delAACGA; p.E234fs*2; 4:184390738-184390742

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaDeletion - Frameshift

c.783G>C; p.Q261H; 4:184389025-184389025

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.827G>A; p.G276D; 4:184388981-184388981

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.408C>G; p.I136M; 4:184418170-184418170

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.820C>T; p.L274L; 4:184388988-184388988

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.826G>A; p.G276S; 4:184388982-184388982

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.58A>T; p.T20S; 4:184429007-184429007

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.122C>T; p.A41V; 4:184419534-184419534

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.858G>A; p.P286P; 4:184388950-184388950

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.532G>A; p.V178I; 4:184399077-184399077

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.857C>T; p.P286L; 4:184388951-184388951

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.102_103insT; p.Q35fs*9; 4:184419553-184419554

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.300G>T; p.K100N; 4:184418596-184418596

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.638C>T; p.P213L; 4:184398971-184398971

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.349C>T; p.R117W; 4:184418547-184418547

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.339C>T; p.P113P; 4:184418557-184418557

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.991C>T; p.R331W; 4:184388817-184388817

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323T>G; p.V108G; 4:184418573-184418573

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1000G>A; p.V334I; 4:184388808-184388808

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.250G>A; p.A84T; 4:184418646-184418646

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.67G>T; p.G23W; 4:184428998-184428998

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.234G>A; p.K78K; 4:184418662-184418662

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.234G>A; p.K78K; 4:184418662-184418662

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.952A>G; p.T318A; 4:184388856-184388856

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1034G>A; p.R345H; 4:184388774-184388774

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.952A>G; p.T318A; 4:184388856-184388856

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.234G>A; p.K78K; 4:184418662-184418662

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.704C>T; p.T235M; 4:184390740-184390740

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.388G>T; p.E130*; 4:184418190-184418190

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.25C>T; p.R9C; 4:184429040-184429040

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.25C>T; p.R9C; 4:184429040-184429040

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.66G>A; p.P22P; 4:184428999-184428999

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.172T>C; p.W58R; 4:184419484-184419484

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.38A>G; p.E13G; 4:184429027-184429027

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.914G>A; p.W305*; 4:184388894-184388894

 livercarcinomaSubstitution - Nonsense

c.312delT; p.N104fs*48; 4:184418584-184418584

 livercarcinomaDeletion - Frameshift

c.412-6_419delTCCTAGCAAGAACC; p.?; 4:184408268-184408281

 livercarcinoma; hepatocellular_carcinomaUnknown

c.409A>C; p.K137Q; 4:184418169-184418169

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1004T>G; p.I335S; 4:184388804-184388804

 livercarcinomaSubstitution - Missense

c.1004T>G; p.I335S; 4:184388804-184388804

 livercarcinomaSubstitution - Missense

c.238A>T; p.N80Y; 4:184418658-184418658

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.477G>T; p.A159A; 4:184408210-184408210

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.248G>T; p.C83F; 4:184418648-184418648

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.711T>C; p.D237D; 4:184390733-184390733

 lungcarcinoma; small_cell_carcinomaSubstitution - coding silent

c.638C>T; p.P213L; 4:184398971-184398971

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.26G>T; p.R9L; 4:184429039-184429039

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.639G>A; p.P213P; 4:184398970-184398970

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.880G>C; p.E294Q; 4:184388928-184388928

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.914G>T; p.W305L; 4:184388894-184388894

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.610G>T; p.E204*; 4:184398999-184398999

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.622G>A; p.E208K; 4:184398987-184398987

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1028A>T; p.Q343L; 4:184388780-184388780

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.825C>G; p.P275P; 4:184388983-184388983

 meningesmeningiomaSubstitution - coding silent

c.679G>A; p.V227M; 4:184398930-184398930

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.358A>T; p.K120*; 4:184418538-184418538

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.172T>C; p.W58R; 4:184419484-184419484

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.541_549delTCCCATCTG; p.S181_L183delSHL; 4:184399060-184399068

 ovarycarcinoma; serous_carcinomaDeletion - In frame

c.758G>A; p.R253Q; 4:184389050-184389050

 pancreascarcinomaSubstitution - Missense

c.758G>A; p.R253Q; 4:184389050-184389050

 pancreascarcinomaSubstitution - Missense

c.892C>G; p.P298A; 4:184388916-184388916

 pancreascarcinomaSubstitution - Missense

c.758G>T; p.R253L; 4:184389050-184389050

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.694+4A>T; p.?; 4:184398911-184398911

 prostatecarcinomaUnknown

c.676C>G; p.P226A; 4:184398933-184398933

 skinmalignant_melanomaSubstitution - Missense

c.935C>T; p.P312L; 4:184388873-184388873

 skinmalignant_melanomaSubstitution - Missense

c.940T>G; p.S314A; 4:184388868-184388868

 skinmalignant_melanomaSubstitution - Missense

c.700G>A; p.E234K; 4:184390744-184390744

 skinmalignant_melanomaSubstitution - Missense

c.962C>T; p.S321F; 4:184388846-184388846

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.187+2T>C; p.?; 4:184419467-184419467

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.469G>A; p.E157K; 4:184408218-184408218

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.250G>A; p.A84T; 4:184418646-184418646

 skin; solemalignant_melanoma; acral_lentiginousSubstitution - Missense

c.529G>A; p.V177I; 4:184408158-184408158

 skinmalignant_melanomaSubstitution - Missense

c.108C>T; p.I36I; 4:184419548-184419548

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.108C>T; p.I36I; 4:184419548-184419548

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.948C>T; p.S316S; 4:184388860-184388860

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.93G>A; p.K31K; 4:184419563-184419563

 skinmalignant_melanomaSubstitution - coding silent

c.359A>C; p.K120T; 4:184418537-184418537

 skin; legmalignant_melanomaSubstitution - Missense

c.674C>T; p.S225F; 4:184398935-184398935

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.103C>T; p.Q35*; 4:184419553-184419553

 skinmalignant_melanomaSubstitution - Nonsense

c.338C>T; p.P113L; 4:184418558-184418558

 skin; trunkmalignant_melanomaSubstitution - Missense

c.1032C>T; p.A344A; 4:184388776-184388776

 skinmalignant_melanomaSubstitution - coding silent

c.122C>T; p.A41V; 4:184419534-184419534

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.122C>T; p.A41V; 4:184419534-184419534

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.363A>G; p.K121K; 4:184418533-184418533

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.191A>C; p.K64T; 4:184418705-184418705

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.349C>T; p.R117W; 4:184418547-184418547

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.174G>T; p.W58C; 4:184419482-184419482

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.236C>T; p.A79V; 4:184418660-184418660

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1000G>A; p.V334I; 4:184388808-184388808

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.321G>T; p.R107S; 4:184418575-184418575

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.500delA; p.N167fs*7; 4:184408187-184408187

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.868G>A; p.V290I; 4:184388940-184388940

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.744G>A; p.G248G; 4:184389064-184389064

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.365-2A>T; p.?; 4:184418215-184418215

 stomachcarcinoma; adenocarcinomaUnknown

c.160C>G; p.L54V; 4:184419496-184419496

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.103C>T; p.Q35*; 4:184419553-184419553

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.250G>C; p.A84P; 4:184418646-184418646

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.412-1G>A; p.?; 4:184408276-184408276

 stomachcarcinoma; adenocarcinomaUnknown

c.37G>T; p.E13*; 4:184429028-184429028

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1008G>A; p.K336K; 4:184388800-184388800

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.745C>T; p.R249W; 4:184389063-184389063

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - Missense

c.187G>A; p.G63R; 4:184419469-184419469

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.37G>C; p.E13Q; 4:184429028-184429028

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.37G>C; p.E13Q; 4:184429028-184429028

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.37G>C; p.E13Q; 4:184429028-184429028

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.236C>T; p.A79V; 4:184418660-184418660

 urinary_tract; bladdercarcinomaSubstitution - Missense