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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

331

Name

XIAP

Synonymous

X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase;XIAP;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

Definition

E3 ubiquitin-protein ligase XIAP|IAP-like protein|X-linked IAP|baculoviral IAP repeat-containing protein 4|inhibitor of apoptosis protein 3

Position

Xq25

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.269G>A; p.C90Y; 23:123885931-123885931

 breastcarcinomaSubstitution - Missense

c.699G>A; p.R233R; 23:123886361-123886361

 breastcarcinomaSubstitution - coding silent

c.1461C>G; p.V487V; 23:123907148-123907148

 breastcarcinomaSubstitution - coding silent

c.285C>A; p.G95G; 23:123885947-123885947

 breastcarcinomaSubstitution - coding silent

c.358T>A; p.Y120N; 23:123886020-123886020

 breastcarcinomaSubstitution - Missense

c.584G>C; p.G195A; 23:123886246-123886246

 central_nervous_system; braingliomaSubstitution - Missense

c.1184A>G; p.E395G; 23:123900577-123900577

 central_nervous_system; braingliomaSubstitution - Missense

c.1262G>A; p.S421N; 23:123900655-123900655

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.703C>A; p.L235I; 23:123886365-123886365

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1132G>A; p.E378K; 23:123900525-123900525

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.26C>A; p.S9Y; 23:123885688-123885688

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.86G>T; p.R29I; 23:123885748-123885748

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1016T>C; p.I339T; 23:123891276-123891276

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.504G>T; p.K168N; 23:123886166-123886166

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.698G>A; p.R233Q; 23:123886360-123886360

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.64G>T; p.E22*; 23:123885726-123885726

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.157C>A; p.L53I; 23:123885819-123885819

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1199C>A; p.S400Y; 23:123900592-123900592

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1345C>T; p.L449F; 23:123907032-123907032

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1121C>A; p.P374H; 23:123900514-123900514

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.309G>A; p.T103T; 23:123885971-123885971

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1056+2T>C; p.?; 23:123891318-123891318

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.776A>G; p.N259S; 23:123886438-123886438

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.872C>T; p.A291V; 23:123886534-123886534

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.470A>G; p.N157S; 23:123886132-123886132

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1162G>A; p.D388N; 23:123900555-123900555

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.349G>C; p.V117L; 23:123886011-123886011

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.347A>G; p.K116R; 23:123886009-123886009

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.713G>A; p.R238Q; 23:123886375-123886375

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.713G>A; p.R238Q; 23:123886375-123886375

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.2T>C; p.M1T; 23:123885664-123885664

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1479A>C; p.K493N; 23:123907166-123907166

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.533A>G; p.H178R; 23:123886195-123886195

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1268A>C; p.Q423P; 23:123900661-123900661

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1206C>T; p.S402S; 23:123900599-123900599

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.536T>C; p.L179P; 23:123886198-123886198

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.669C>T; p.H223H; 23:123886331-123886331

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.716G>A; p.S239N; 23:123886378-123886378

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1145T>C; p.M382T; 23:123900538-123900538

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.117T>C; p.G39G; 23:123885779-123885779

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.773G>T; p.R258I; 23:123886435-123886435

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.766C>A; p.L256I; 23:123886428-123886428

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1482T>G; p.I494M; 23:123907169-123907169

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1191T>G; p.I397M; 23:123900584-123900584

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.54T>C; p.N18N; 23:123885716-123885716

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.132A>G; p.A44A; 23:123885794-123885794

 livercarcinomaSubstitution - coding silent

c.132A>G; p.A44A; 23:123885794-123885794

 livercarcinomaSubstitution - coding silent

c.493G>T; p.A165S; 23:123886155-123886155

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.493G>T; p.A165S; 23:123886155-123886155

 livercarcinomaSubstitution - Missense

c.1349G>T; p.C450F; 23:123907036-123907036

 livercarcinomaSubstitution - Missense

c.819G>A; p.G273G; 23:123886481-123886481

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.481T>A; p.Y161N; 23:123886143-123886143

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1415A>G; p.K472R; 23:123907102-123907102

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1235C>T; p.A412V; 23:123900628-123900628

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.270C>A; p.C90*; 23:123885932-123885932

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.263C>A; p.P88Q; 23:123885925-123885925

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.447A>G; p.I149M; 23:123886109-123886109

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.249C>A; p.H83Q; 23:123885911-123885911

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.766C>G; p.L256V; 23:123886428-123886428

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.766C>G; p.L256V; 23:123886428-123886428

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.233C>A; p.S78*; 23:123885895-123885895

 lungcarcinoma; small_cell_carcinomaSubstitution - Nonsense

c.1310C>T; p.T437I; 23:123906997-123906997

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1339G>T; p.E447*; 23:123907026-123907026

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1138A>G; p.I380V; 23:123900531-123900531

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.116G>A; p.G39D; 23:123885778-123885778

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.786G>T; p.M262I; 23:123886448-123886448

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1474C>A; p.Q492K; 23:123907161-123907161

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.252G>T; p.R84S; 23:123885914-123885914

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.978G>A; p.G326G; 23:123891238-123891238

 ovaryother; neoplasmSubstitution - coding silent

c.1109T>C; p.I370T; 23:123900502-123900502

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1385T>A; p.F462Y; 23:123907072-123907072

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.533A>G; p.H178R; 23:123886195-123886195

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1336G>C; p.E446Q; 23:123907023-123907023

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.185G>A; p.R62Q; 23:123885847-123885847

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1120C>T; p.P374S; 23:123900513-123900513

 skinmalignant_melanomaSubstitution - Missense

c.1240C>T; p.L414L; 23:123900633-123900633

 skinmalignant_melanomaSubstitution - coding silent

c.904C>T; p.H302Y; 23:123888645-123888645

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.156T>C; p.F52F; 23:123885818-123885818

 skinmalignant_melanomaSubstitution - coding silent

c.934_935CC>TT; p.P312F; 23:123888675-123888676

 skinmalignant_melanomaSubstitution - Missense

c.592G>A; p.V198M; 23:123886254-123886254

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.713G>A; p.R238Q; 23:123886375-123886375

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.192T>G; p.F64L; 23:123885854-123885854

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1192C>T; p.Q398*; 23:123900585-123900585

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1440G>A; p.K480K; 23:123907127-123907127

 urinary_tract; bladdercarcinomaSubstitution - coding silent