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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3308

Name

HSPA4

Synonymous

heat shock 70kDa protein 4;HSPA4;heat shock 70kDa protein 4

Definition

epididymis secretory sperm binding protein Li 5a|heat shock 70 kDa protein 4|heat shock 70-related protein APG-2|heat shock 70kD protein 4|heat shock protein, 110 kDa|hsp70 RY

Position

5q31.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.2504C>G; p.P835R; 5:133104417-133104417

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.108-1G>T; p.?; 5:133064979-133064979

 autonomic_ganglianeuroblastomaUnknown

c.2147T>C; p.F716S; 5:133101868-133101868

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.1854G>A; p.K618K; 5:133097211-133097211

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.6G>C; p.S2S; 5:133052256-133052256

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.2392_2406del15; p.K798_Q802delKNAEQ; 5:133104305-133104319

 breastcarcinomaDeletion - In frame

c.268G>T; p.D90Y; 5:133067519-133067519

 breastcarcinomaSubstitution - Missense

c.1210C>T; p.L404L; 5:133089127-133089127

 breastcarcinomaSubstitution - coding silent

c.2252T>C; p.L751P; 5:133103959-133103959

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.1194A>G; p.V398V; 5:133089111-133089111

 breastcarcinomaSubstitution - coding silent

c.807G>C; p.E269D; 5:133076797-133076797

 breastcarcinomaSubstitution - Missense

c.254C>G; p.S85C; 5:133067505-133067505

 breastcarcinomaSubstitution - Missense

c.794G>A; p.R265Q; 5:133076784-133076784

 breastcarcinomaSubstitution - Missense

c.1585C>A; p.P529T; 5:133092724-133092724

 breastcarcinomaSubstitution - Missense

c.2431G>T; p.D811Y; 5:133104344-133104344

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.2431G>T; p.D811Y; 5:133104344-133104344

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastomaSubstitution - Missense

c.646A>G; p.N216D; 5:133074109-133074109

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.160A>C; p.S54R; 5:133065032-133065032

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.289G>T; p.G97*; 5:133067540-133067540

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1037G>A; p.R346Q; 5:133088455-133088455

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1129G>A; p.A377T; 5:133088547-133088547

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1276G>T; p.A426S; 5:133089593-133089593

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.2398G>A; p.A800T; 5:133104311-133104311

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.665T>C; p.V222A; 5:133076655-133076655

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.140C>T; p.S47L; 5:133065012-133065012

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1542G>A; p.Q514Q; 5:133091356-133091356

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.655A>T; p.K219*; 5:133074118-133074118

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.2397T>C; p.N799N; 5:133104310-133104310

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2483C>T; p.S828L; 5:133104396-133104396

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.822G>T; p.K274N; 5:133076812-133076812

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.739G>T; p.E247*; 5:133076729-133076729

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.794G>A; p.R265Q; 5:133076784-133076784

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.388G>A; p.E130K; 5:133070455-133070455

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.589A>T; p.N197Y; 5:133074052-133074052

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.914A>C; p.K305T; 5:133086787-133086787

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1774G>T; p.E592*; 5:133096221-133096221

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.19G>T; p.D7Y; 5:133052269-133052269

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1757T>A; p.L586*; 5:133096204-133096204

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Nonsense

c.1069T>A; p.F357I; 5:133088487-133088487

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1045G>T; p.A349S; 5:133088463-133088463

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.229G>A; p.D77N; 5:133067480-133067480

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.2252T>C; p.L751P; 5:133103959-133103959

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1719G>C; p.K573N; 5:133096166-133096166

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1431A>C; p.K477N; 5:133091245-133091245

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1067A>C; p.K356T; 5:133088485-133088485

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1254A>G; p.E418E; 5:133089571-133089571

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.428C>T; p.S143L; 5:133070495-133070495

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2319+10G>A; p.?; 5:133104036-133104036

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.1000G>A; p.D334N; 5:133088418-133088418

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.903G>T; p.M301I; 5:133076893-133076893

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2062C>T; p.R688C; 5:133101783-133101783

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.449A>G; p.D150G; 5:133073249-133073249

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2260A>G; p.K754E; 5:133103967-133103967

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1081G>T; p.E361*; 5:133088499-133088499

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1448G>A; p.R483Q; 5:133091262-133091262

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.2252T>C; p.L751P; 5:133103959-133103959

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.715G>A; p.V239M; 5:133076705-133076705

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.2390delA; p.N799fs*>42; 5:133104303-133104303

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.2390delA; p.N799fs*>42; 5:133104303-133104303

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.2390delA; p.N799fs*>42; 5:133104303-133104303

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1877A>T; p.Y626F; 5:133097234-133097234

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.745G>A; p.G249R; 5:133076735-133076735

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.822G>T; p.K274N; 5:133076812-133076812

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1546G>T; p.A516S; 5:133091360-133091360

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.802C>G; p.Q268E; 5:133076792-133076792

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.914A>C; p.K305T; 5:133086787-133086787

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.775delA; p.I260fs*17; 5:133076765-133076765

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1893G>A; p.K631K; 5:133097250-133097250

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.2203_2204insA; p.S737fs*4; 5:133103910-133103911

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.332A>G; p.N111S; 5:133070399-133070399

 livercarcinomaSubstitution - Missense

c.332A>G; p.N111S; 5:133070399-133070399

 livercarcinomaSubstitution - Missense

c.2408A>G; p.N803S; 5:133104321-133104321

 livercarcinomaSubstitution - Missense

c.2408A>G; p.N803S; 5:133104321-133104321

 livercarcinomaSubstitution - Missense

c.908+9A>G; p.?; 5:133076907-133076907

 livercarcinomaUnknown

c.1000G>T; p.D334Y; 5:133088418-133088418

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.546A>C; p.G182G; 5:133074009-133074009

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.632C>T; p.S211F; 5:133074095-133074095

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.2084G>C; p.R695P; 5:133101805-133101805

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.321G>A; p.E107E; 5:133070388-133070388

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.947G>T; p.R316I; 5:133086820-133086820

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.551A>G; p.Y184C; 5:133074014-133074014

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1048G>T; p.V350L; 5:133088466-133088466

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.566C>T; p.P189L; 5:133074029-133074029

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1487C>G; p.S496C; 5:133091301-133091301

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1933C>G; p.R645G; 5:133099548-133099548

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.1201C>T; p.P401S; 5:133089118-133089118

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.562C>T; p.L188F; 5:133074025-133074025

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1488T>G; p.S496S; 5:133091302-133091302

 NSNSSubstitution - coding silent

c.2385G>C; p.E795D; 5:133104298-133104298

 NSNSSubstitution - Missense

c.138T>C; p.R46R; 5:133065010-133065010

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1110A>G; p.E370E; 5:133088528-133088528

 pancreascarcinomaSubstitution - coding silent

c.99C>T; p.R33R; 5:133052349-133052349

 pancreascarcinomaSubstitution - coding silent

c.845C>T; p.S282L; 5:133076835-133076835

 pancreascarcinomaSubstitution - Missense

c.1481G>A; p.S494N; 5:133091295-133091295

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1294C>T; p.L432F; 5:133089611-133089611

 skinmalignant_melanomaSubstitution - Missense

c.1348C>T; p.Q450*; 5:133089665-133089665

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1262C>T; p.S421F; 5:133089579-133089579

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.155C>T; p.A52V; 5:133065027-133065027

 skinmalignant_melanomaSubstitution - Missense

c.1957G>A; p.E653K; 5:133099572-133099572

 skinmalignant_melanomaSubstitution - Missense

c.506G>A; p.R169Q; 5:133073306-133073306

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.817C>T; p.L273F; 5:133076807-133076807

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.780C>T; p.I260I; 5:133076770-133076770

 skinmalignant_melanomaSubstitution - coding silent

c.2273C>T; p.T758I; 5:133103980-133103980

 skinmalignant_melanomaSubstitution - Missense

c.562C>T; p.L188F; 5:133074025-133074025

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2440G>T; p.G814C; 5:133104353-133104353

 skinmalignant_melanomaSubstitution - Missense

c.1037G>A; p.R346Q; 5:133088455-133088455

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.832A>T; p.S278C; 5:133076822-133076822

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1584A>G; p.E528E; 5:133092723-133092723

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1756T>G; p.L586V; 5:133096203-133096203

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1240T>C; p.S414P; 5:133089157-133089157

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.986-1G>C; p.?; 5:133088403-133088403

 stomachcarcinoma; intestinal_adenocarcinomaUnknown

c.333_334insT; p.T113fs*3; 5:133070400-133070401

 stomachcarcinoma; intestinal_adenocarcinomaInsertion - Frameshift

c.1138-4C>T; p.?; 5:133089051-133089051

 stomachcarcinoma; adenocarcinomaUnknown

c.1571T>G; p.V524G; 5:133092710-133092710

 thyroidother; neoplasmSubstitution - Missense

c.736G>T; p.E246*; 5:133076726-133076726

 thyroidother; neoplasmSubstitution - Nonsense

c.136C>T; p.R46C; 5:133065008-133065008

 thyroidcarcinomaSubstitution - Missense

c.2298A>C; p.K766N; 5:133104005-133104005

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1062C>T; p.I354I; 5:133088480-133088480

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1116C>G; p.V372V; 5:133088534-133088534

 urinary_tract; bladdercarcinomaSubstitution - coding silent