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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

329

Name

BIRC2

Synonymous

baculoviral IAP repeat containing 2;BIRC2;baculoviral IAP repeat containing 2

Definition

IAP homolog B|IAP-2|NFR2-TRAF signalling complex protein|RING finger protein 48|TNFR2-TRAF-signaling complex protein 2|apoptosis inhibitor 1|baculoviral IAP repeat-containing 2|baculoviral IAP repeat-containing protein 2|inhibitor of apoptosis protein 2

Position

11q22

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.93G>T; p.W31C; 11:102349947-102349947

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.378G>T; p.K126N; 11:102350232-102350232

 breastcarcinomaSubstitution - Missense

c.907G>T; p.D303Y; 11:102350855-102350855

 breastcarcinomaSubstitution - Missense

c.605C>G; p.S202*; 11:102350459-102350459

 breastcarcinoma; HER-positive_carcinomaSubstitution - Nonsense

c.1356A>C; p.E452D; 11:102368538-102368538

 breastcarcinomaSubstitution - Missense

c.91T>A; p.W31R; 11:102349945-102349945

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.206G>T; p.R69L; 11:102350060-102350060

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1008G>C; p.L336F; 11:102362908-102362908

 central_nervous_system; thalamusglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1785T>C; p.C595C; 11:102378111-102378111

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.533G>T; p.S178I; 11:102350387-102350387

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1522G>T; p.E508*; 11:102377651-102377651

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.758C>A; p.S253Y; 11:102350612-102350612

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.27T>G; p.L9L; 11:102349881-102349881

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1005C>A; p.F335L; 11:102362905-102362905

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1005C>A; p.F335L; 11:102362905-102362905

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.892G>A; p.V298M; 11:102350746-102350746

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1303C>G; p.L435V; 11:102368485-102368485

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.582G>A; p.W194*; 11:102350436-102350436

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.542T>C; p.M181T; 11:102350396-102350396

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1739C>A; p.S580Y; 11:102378065-102378065

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1780G>A; p.E594K; 11:102378106-102378106

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.946T>C; p.W316R; 11:102350894-102350894

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.946T>C; p.W316R; 11:102350894-102350894

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.545G>A; p.S182N; 11:102350399-102350399

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1350T>C; p.A450A; 11:102368532-102368532

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.1193C>A; p.S398Y; 11:102368375-102368375

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.86C>T; p.S29L; 11:102349940-102349940

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.896-1G>T; p.?; 11:102350843-102350843

 kidneyother; neoplasmUnknown

c.994A>G; p.R332G; 11:102350942-102350942

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1013G>T; p.R338L; 11:102362913-102362913

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.352T>G; p.S118A; 11:102350206-102350206

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1686G>A; p.L562L; 11:102378012-102378012

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.709A>G; p.M237V; 11:102350563-102350563

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.980C>T; p.A327V; 11:102350928-102350928

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1522G>T; p.E508*; 11:102377651-102377651

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.758C>A; p.S253Y; 11:102350612-102350612

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.235G>T; p.D79Y; 11:102350089-102350089

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1622T>C; p.V541A; 11:102377857-102377857

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.832T>C; p.Y278H; 11:102350686-102350686

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.811G>A; p.A271T; 11:102350665-102350665

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.62T>C; p.I21T; 11:102349916-102349916

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1323A>C; p.K441N; 11:102368505-102368505

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1036G>T; p.D346Y; 11:102362936-102362936

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1734A>C; p.E578D; 11:102378060-102378060

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.430G>C; p.E144Q; 11:102350284-102350284

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.454T>C; p.S152P; 11:102350308-102350308

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.263T>C; p.L88P; 11:102350117-102350117

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.699G>T; p.K233N; 11:102350553-102350553

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1384C>T; p.R462W; 11:102377513-102377513

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1266G>T; p.E422D; 11:102368448-102368448

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.325A>T; p.S109C; 11:102350179-102350179

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1808C>T; p.P603L; 11:102378134-102378134

 livercarcinomaSubstitution - Missense

c.1808C>T; p.P603L; 11:102378134-102378134

 livercarcinomaSubstitution - Missense

c.1723A>G; p.M575V; 11:102378049-102378049

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1723A>G; p.M575V; 11:102378049-102378049

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1366+1G>T; p.?; 11:102368549-102368549

 lung; right_upper_lobecarcinoma; adenocarcinomaUnknown

c.744A>G; p.P248P; 11:102350598-102350598

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.171C>T; p.P57P; 11:102350025-102350025

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1225G>T; p.V409L; 11:102368407-102368407

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.555A>T; p.E185D; 11:102350409-102350409

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.956G>A; p.G319E; 11:102350904-102350904

 lungcarcinoma; undifferentiated_carcinomaSubstitution - Missense

c.1026A>T; p.Q342H; 11:102362926-102362926

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.548C>T; p.T183I; 11:102350402-102350402

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.638G>T; p.G213V; 11:102350492-102350492

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.992C>A; p.P331Q; 11:102350940-102350940

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.270G>T; p.L90L; 11:102350124-102350124

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.533G>T; p.S178I; 11:102350387-102350387

 oesophaguscarcinomaSubstitution - Missense

c.973G>C; p.E325Q; 11:102350921-102350921

 oesophaguscarcinomaSubstitution - Missense

c.958G>A; p.D320N; 11:102350906-102350906

 oesophaguscarcinomaSubstitution - Missense

c.406G>C; p.A136P; 11:102350260-102350260

 oesophaguscarcinomaSubstitution - Missense

c.1124T>A; p.I375N; 11:102368306-102368306

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.962A>G; p.D321G; 11:102350910-102350910

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.779G>C; p.S260T; 11:102350633-102350633

 oesophaguscarcinomaSubstitution - Missense

c.327C>T; p.S109S; 11:102350181-102350181

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1748T>A; p.F583Y; 11:102378074-102378074

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.1748T>A; p.F583Y; 11:102378074-102378074

 pancreascarcinomaSubstitution - Missense

c.1598C>G; p.S533C; 11:102377727-102377727

 parathyroidcarcinomaSubstitution - Missense

c.714A>C; p.S238S; 11:102350568-102350568

 prostatecarcinomaSubstitution - coding silent

c.1501C>G; p.Q501E; 11:102377630-102377630

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1565A>G; p.N522S; 11:102377694-102377694

 skinmalignant_melanomaSubstitution - Missense

c.467T>A; p.L156H; 11:102350321-102350321

 skinmalignant_melanomaSubstitution - Missense

c.515C>A; p.S172*; 11:102350369-102350369

 skinmalignant_melanomaSubstitution - Nonsense

c.421C>T; p.P141S; 11:102350275-102350275

 skinmalignant_melanomaSubstitution - Missense

c.1129C>T; p.H377Y; 11:102368311-102368311

 skinmalignant_melanomaSubstitution - Missense

c.1430C>T; p.P477L; 11:102377559-102377559

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.17C>T; p.S6F; 11:102349871-102349871

 skin; trunkmalignant_melanomaSubstitution - Missense

c.451G>A; p.G151S; 11:102350305-102350305

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.181C>T; p.P61S; 11:102350035-102350035

 skinmalignant_melanomaSubstitution - Missense

c.1828A>G; p.K610E; 11:102378154-102378154

 skinmalignant_melanomaSubstitution - Missense

c.346C>G; p.L116V; 11:102350200-102350200

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1692G>A; p.R564R; 11:102378018-102378018

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.575A>G; p.H192R; 11:102350429-102350429

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.41C>T; p.S14L; 11:102349895-102349895

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1517C>T; p.A506V; 11:102377646-102377646

 thyroidother; neoplasmSubstitution - Missense

c.1468A>G; p.K490E; 11:102377597-102377597

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.491G>T; p.R164I; 11:102350345-102350345

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.491G>T; p.R164I; 11:102350345-102350345

 urinary_tract; bladdercarcinomaSubstitution - Missense