Entrez Gene

Basic Information
Gene ID	3198
Name	HOXA1
Synonymous	homeobox A1;HOXA1;homeobox A1
Definition	HOX A1 homeodomain protein\|Hox 1.6-like protein\|homeo box A1\|homeobox 1F\|homeobox protein Hox-1F\|homeobox protein Hox-A1\|lab-like protein
Position	7p15.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.258G>T; p.L86L; 7:27095655-27095655	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.838C>T; p.R280C; 7:27094610-27094610	breast	carcinoma	Substitution - Missense
c.582C>T; p.P194P; 7:27095331-27095331	breast	carcinoma	Substitution - coding silent
c.216_218delTCG; p.R73delR; 7:27095695-27095697	breast	carcinoma	Deletion - In frame
c.583G>A; p.A195T; 7:27095330-27095330	breast	carcinoma	Substitution - Missense
c.200A>C; p.H67P; 7:27095713-27095713	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.284G>A; p.C95Y; 7:27095629-27095629	central_nervous_system; brain	glioma	Substitution - Missense
c.580C>T; p.P194S; 7:27095333-27095333	central_nervous_system; brain	glioma	Substitution - Missense
c.773G>A; p.R258H; 7:27094675-27094675	central_nervous_system; temporoparietal	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.692C>T; p.A231V; 7:27094756-27094756	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.221A>G; p.H74R; 7:27095692-27095692	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.947C>A; p.S316Y; 7:27094501-27094501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.697C>T; p.R233C; 7:27094751-27094751	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.154C>T; p.R52C; 7:27095759-27095759	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.180G>T; p.Q60H; 7:27095733-27095733	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.854A>T; p.K285M; 7:27094594-27094594	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.521C>T; p.A174V; 7:27095392-27095392	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.773G>A; p.R258H; 7:27094675-27094675	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.207_215delCCACCACCA; p.H70_H72delHHH; 7:27095698-27095706	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Deletion - In frame
c.790G>T; p.A264S; 7:27094658-27094658	kidney	other; neoplasm	Substitution - Missense
c.733G>A; p.E245K; 7:27094715-27094715	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.713C>A; p.T238N; 7:27094735-27094735	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.877T>C; p.L293L; 7:27094571-27094571	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.412C>T; p.P138S; 7:27095501-27095501	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.226delC; p.Q76fs*38; 7:27095687-27095687	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.215_216insCCA; p.H72_R73insH; 7:27095697-27095698	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - In frame
c.215_216insCCA; p.H72_R73insH; 7:27095697-27095698	large_intestine	carcinoma; adenocarcinoma	Insertion - In frame
c.194A>C; p.H65P; 7:27095719-27095719	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.822G>A; p.K274K; 7:27094626-27094626	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.334G>A; p.A112T; 7:27095579-27095579	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.281G>T; p.S94I; 7:27095632-27095632	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.950C>T; p.S317L; 7:27094498-27094498	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.333C>T; p.Y111Y; 7:27095580-27095580	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.738G>A; p.K246K; 7:27094710-27094710	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.922G>A; p.E308K; 7:27094526-27094526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.216_218delTCG; p.R73delR; 7:27095695-27095697	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.335C>T; p.A112V; 7:27095578-27095578	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.87_88insA; p.S30fs*4; 7:27095825-27095826	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.175delG; p.V59fs*55; 7:27095738-27095738	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.213_215delCCA; p.H72delH; 7:27095698-27095700	large_intestine	carcinoma; adenocarcinoma	Deletion - In frame
c.652G>T; p.G218W; 7:27095261-27095261	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.652G>T; p.G218W; 7:27095261-27095261	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.697C>T; p.R233C; 7:27094751-27094751	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.397G>A; p.G133R; 7:27095516-27095516	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.121G>A; p.A41T; 7:27095792-27095792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.553G>A; p.A185T; 7:27095360-27095360	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.207_215delCCACCACCA; p.H70_H72delHHH; 7:27095698-27095706	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.773G>A; p.R258H; 7:27094675-27094675	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.913G>A; p.E305K; 7:27094535-27094535	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.859C>T; p.R287C; 7:27094589-27094589	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.494G>C; p.G165A; 7:27095419-27095419	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.797T>A; p.L266Q; 7:27094651-27094651	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.377G>T; p.C126F; 7:27095536-27095536	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.693G>A; p.A231A; 7:27094755-27094755	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.205C>A; p.H69N; 7:27095708-27095708	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.644C>A; p.P215H; 7:27095269-27095269	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.514G>T; p.A172S; 7:27095399-27095399	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.652G>T; p.G218W; 7:27095261-27095261	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.356T>A; p.V119E; 7:27095557-27095557	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.989C>G; p.T330S; 7:27094459-27094459	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.146G>T; p.G49V; 7:27095767-27095767	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.513G>T; p.L171L; 7:27095400-27095400	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.123G>T; p.A41A; 7:27095790-27095790	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.766C>T; p.R256C; 7:27094682-27094682	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.932C>A; p.S311*; 7:27094516-27094516	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.962C>A; p.P321H; 7:27094486-27094486	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.186T>C; p.G62G; 7:27095727-27095727	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.575G>A; p.R192H; 7:27095338-27095338	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.531_533delTAA; p.N178delN; 7:27095380-27095382	oesophagus	carcinoma; adenocarcinoma	Deletion - In frame
c.505C>T; p.Q169*; 7:27095408-27095408	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.945C>T; p.S315S; 7:27094503-27094503	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.398G>A; p.G133E; 7:27095515-27095515	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.47G>C; p.S16T; 7:27095866-27095866	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.555C>A; p.A185A; 7:27095358-27095358	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.431A>T; p.H144L; 7:27095482-27095482	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.41T>C; p.I14T; 7:27095872-27095872	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.41T>C; p.I14T; 7:27095872-27095872	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.252G>T; p.G84G; 7:27095661-27095661	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.59C>T; p.S20L; 7:27095854-27095854	pancreas	carcinoma	Substitution - Missense
c.859C>T; p.R287C; 7:27094589-27094589	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.909C>T; p.N303N; 7:27094539-27094539	prostate	carcinoma	Substitution - coding silent
c.583G>A; p.A195T; 7:27095330-27095330	prostate	carcinoma	Substitution - Missense
c.252G>A; p.G84G; 7:27095661-27095661	skin	malignant_melanoma	Substitution - coding silent
c.829T>C; p.F277L; 7:27094619-27094619	skin	malignant_melanoma	Substitution - Missense
c.260G>A; p.G87E; 7:27095653-27095653	skin	malignant_melanoma	Substitution - Missense
c.4G>A; p.D2N; 7:27095909-27095909	skin	malignant_melanoma	Substitution - Missense
c.786C>T; p.I262I; 7:27094662-27094662	skin	malignant_melanoma	Substitution - coding silent
c.671G>A; p.G224D; 7:27094777-27094777	skin	malignant_melanoma	Substitution - Missense
c.27C>T; p.F9F; 7:27095886-27095886	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.728A>T; p.E243V; 7:27094720-27094720	skin	malignant_melanoma	Substitution - Missense
c.112C>T; p.Q38*; 7:27095801-27095801	skin	malignant_melanoma	Substitution - Nonsense
c.981C>T; p.T327T; 7:27094467-27094467	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.840C>T; p.R280R; 7:27094608-27094608	skin	malignant_melanoma	Substitution - coding silent
c.654G>A; p.G218G; 7:27094794-27094794	skin	malignant_melanoma	Substitution - coding silent
c.587C>T; p.S196L; 7:27095326-27095326	skin	malignant_melanoma	Substitution - Missense
c.165G>A; p.V55V; 7:27095748-27095748	skin	malignant_melanoma	Substitution - coding silent
c.91G>A; p.D31N; 7:27095822-27095822	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.122C>T; p.A41V; 7:27095791-27095791	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.520G>T; p.A174S; 7:27095393-27095393	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.378C>T; p.C126C; 7:27095535-27095535	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.697C>T; p.R233C; 7:27094751-27094751	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.697C>T; p.R233C; 7:27094751-27094751	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.146G>A; p.G49D; 7:27095767-27095767	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.769G>A; p.A257T; 7:27094679-27094679	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.218G>A; p.R73H; 7:27095695-27095695	thyroid	other; neoplasm	Substitution - Missense
c.638A>G; p.N213S; 7:27095275-27095275	thyroid	carcinoma	Substitution - Missense
c.213C>T; p.H71H; 7:27095700-27095700	thyroid	other; neoplasm	Substitution - coding silent
c.851A>G; p.Q284R; 7:27094597-27094597	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.216_218delTCG; p.R73delR; 7:27095695-27095697	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.216_218delTCG; p.R73delR; 7:27095695-27095697	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.216_218delTCG; p.R73delR; 7:27095695-27095697	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.216_218delTCG; p.R73delR; 7:27095695-27095697	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - In frame
c.126C>T; p.V42V; 7:27095787-27095787	urinary_tract; bladder	carcinoma	Substitution - coding silent

Oncogene database

COSMIC confirmed somatic mutation [Top]

Bioinformatics and cancer genomics links

Bioinformatics centers

Bioinformatics centers

Welcome to Bioinfo-MinZhao!