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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3169

Name

FOXA1

Synonymous

forkhead box A1;FOXA1;forkhead box A1

Definition

HNF-3-alpha|HNF-3A|TCF-3A|forkhead box protein A1|hepatocyte nuclear factor 3-alpha|transcription factor 3A

Position

14q21.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1416C>G; p.S472S; 14:37591368-37591368

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.1328C>T; p.S443L; 14:37591456-37591456

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.1169G>A; p.G390E; 14:37591615-37591615

 boneosteosarcomaSubstitution - Missense

c.149T>G; p.M50R; 14:37592635-37592635

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.528C>G; p.I176M; 14:37592256-37592256

 breastcarcinomaSubstitution - Missense

c.528C>G; p.I176M; 14:37592256-37592256

 breastcarcinomaSubstitution - Missense

c.528C>G; p.I176M; 14:37592256-37592256

 breastcarcinomaSubstitution - Missense

c.776A>C; p.Y259S; 14:37592008-37592008

 breastcarcinomaSubstitution - Missense

c.741C>G; p.H247Q; 14:37592043-37592043

 breastcarcinomaSubstitution - Missense

c.579delG; p.S194fs*127; 14:37592205-37592205

 breastcarcinomaDeletion - Frameshift

c.676G>A; p.D226N; 14:37592108-37592108

 breastcarcinomaSubstitution - Missense

c.764A>T; p.E255V; 14:37592020-37592020

 breastcarcinomaSubstitution - Missense

c.767A>T; p.N256I; 14:37592017-37592017

 breastcarcinomaSubstitution - Missense

c.99_105delCATGAAC; p.M34fs*6; 14:37592679-37592685

 breastcarcinomaDeletion - Frameshift

c.739C>T; p.H247Y; 14:37592045-37592045

 breastcarcinomaSubstitution - Missense

c.757_761delATGTT; p.M253fs*38; 14:37592023-37592027

 breastcarcinomaDeletion - Frameshift

c.677A>G; p.D226G; 14:37592107-37592107

 breastcarcinomaSubstitution - Missense

c.526A>G; p.I176V; 14:37592258-37592258

 breastcarcinomaSubstitution - Missense

c.458C>T; p.A153V; 14:37592326-37592326

 breastcarcinomaSubstitution - Missense

c.649T>C; p.S217P; 14:37592135-37592135

 breastcarcinomaSubstitution - Missense

c.1227_1234delGGAGCAGC; p.E410fs*2; 14:37591550-37591557

 breastcarcinomaDeletion - Frameshift

c.749C>T; p.S250F; 14:37592035-37592035

 breastcarcinomaSubstitution - Missense

c.749C>T; p.S250F; 14:37592035-37592035

 breastcarcinomaSubstitution - Missense

c.749C>T; p.S250F; 14:37592035-37592035

 breastcarcinomaSubstitution - Missense

c.590A>G; p.Y197C; 14:37592194-37592194

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.796T>A; p.F266I; 14:37591988-37591988

 breastcarcinomaSubstitution - Missense

c.1241_1242insA; p.L415fs*>59; 14:37591542-37591543

 breastcarcinomaInsertion - Frameshift

c.642G>T; p.W214C; 14:37592142-37592142

 breastcarcinomaSubstitution - Missense

c.301G>A; p.V101M; 14:37592483-37592483

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.301G>A; p.V101M; 14:37592483-37592483

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.462C>T; p.G154G; 14:37592322-37592322

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.462C>T; p.G154G; 14:37592322-37592322

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.85G>A; p.V29I; 14:37592699-37592699

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.474C>T; p.D158D; 14:37592310-37592310

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1092C>T; p.P364P; 14:37591692-37591692

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1354C>G; p.P452A; 14:37591430-37591430

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1320C>T; p.G440G; 14:37591464-37591464

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.82T>C; p.S28P; 14:37592702-37592702

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.462C>T; p.G154G; 14:37592322-37592322

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.685G>A; p.V229I; 14:37592099-37592099

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.638G>A; p.R213H; 14:37592146-37592146

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.557C>T; p.A186V; 14:37592227-37592227

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.504C>T; p.H168H; 14:37592280-37592280

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.431C>T; p.A144V; 14:37592353-37592353

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.951C>T; p.T317T; 14:37591833-37591833

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.645G>A; p.Q215Q; 14:37592139-37592139

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1165A>C; p.K389Q; 14:37591619-37591619

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.1201T>A; p.S401T; 14:37591583-37591583

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.252C>T; p.G84G; 14:37592532-37592532

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.116G>T; p.G39V; 14:37592668-37592668

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.247G>A; p.A83T; 14:37592537-37592537

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.357G>A; p.Q119Q; 14:37592427-37592427

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.340G>T; p.G114C; 14:37592444-37592444

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.263_264insG; p.S89fs*138; 14:37592520-37592521

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.309C>T; p.A103A; 14:37592475-37592475

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.811C>A; p.Q271K; 14:37591973-37591973

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.710A>T; p.K237M; 14:37592074-37592074

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.551A>G; p.Q184R; 14:37592233-37592233

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1302C>T; p.P434P; 14:37591482-37591482

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1111C>T; p.P371S; 14:37591673-37591673

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.552G>A; p.Q184Q; 14:37592232-37592232

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.447C>T; p.G149G; 14:37592337-37592337

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.300C>T; p.G100G; 14:37592484-37592484

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.247G>A; p.A83T; 14:37592537-37592537

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1202C>A; p.S401Y; 14:37591582-37591582

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.528C>G; p.I176M; 14:37592256-37592256

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.472G>A; p.D158N; 14:37592312-37592312

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.378C>A; p.G126G; 14:37592406-37592406

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1168G>T; p.G390W; 14:37591616-37591616

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1362C>T; p.A454A; 14:37591422-37591422

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1085C>A; p.S362Y; 14:37591699-37591699

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.249C>G; p.A83A; 14:37592535-37592535

 oesophaguscarcinomaSubstitution - coding silent

c.725C>G; p.S242C; 14:37592059-37592059

 ovaryother; neoplasmSubstitution - Missense

c.890C>A; p.P297H; 14:37591894-37591894

 pancreascarcinomaSubstitution - Missense

c.1268C>T; p.A423V; 14:37591516-37591516

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1319G>T; p.G440V; 14:37591465-37591465

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.758T>G; p.M253R; 14:37592026-37592026

 prostatecarcinomaSubstitution - Missense

c.758T>G; p.M253R; 14:37592026-37592026

 prostatecarcinomaSubstitution - Missense

c.655C>A; p.R219S; 14:37592129-37592129

 prostatecarcinoma; small_cell_carcinomaSubstitution - Missense

c.1417T>G; p.*473E; 14:37591367-37591367

 prostatecarcinoma; adenocarcinomaNonstop extension

c.676G>A; p.D226N; 14:37592108-37592108

 prostatecarcinomaSubstitution - Missense

c.676G>A; p.D226N; 14:37592108-37592108

 prostatecarcinomaSubstitution - Missense

c.798C>G; p.F266L; 14:37591986-37591986

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.798C>G; p.F266L; 14:37591986-37591986

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.798C>G; p.F266L; 14:37591986-37591986

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.798C>G; p.F266L; 14:37591986-37591986

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.760T>G; p.F254V; 14:37592024-37592024

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1287C>T; p.Y429Y; 14:37591497-37591497

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.366C>T; p.A122A; 14:37592418-37592418

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.739C>T; p.H247Y; 14:37592045-37592045

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1358_1359insGG; p.A454fs*17; 14:37591425-37591426

 prostatecarcinomaInsertion - Frameshift

c.797T>C; p.F266S; 14:37591987-37591987

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.763G>A; p.E255K; 14:37592021-37592021

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.284G>C; p.S95T; 14:37592500-37592500

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.758T>C; p.M253T; 14:37592026-37592026

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.797T>G; p.F266C; 14:37591987-37591987

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.746A>T; p.D249V; 14:37592038-37592038

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.676G>T; p.D226Y; 14:37592108-37592108

 prostatecarcinomaSubstitution - Missense

c.1079delT; p.I360fs*29; 14:37591705-37591705

 prostatecarcinomaDeletion - Frameshift

c.758T>A; p.M253K; 14:37592026-37592026

 prostatecarcinomaSubstitution - Missense

c.758T>A; p.M253K; 14:37592026-37592026

 prostatecarcinomaSubstitution - Missense

c.1020delG; p.T341fs*9; 14:37591764-37591764

 prostatecarcinomaDeletion - Frameshift

c.695C>T; p.A232V; 14:37592089-37592089

 prostatecarcinomaSubstitution - Missense

c.679T>C; p.C227R; 14:37592105-37592105

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1075C>T; p.P359S; 14:37591709-37591709

 skinmalignant_melanomaSubstitution - Missense

c.242C>A; p.A81E; 14:37592542-37592542

 skinmalignant_melanomaSubstitution - Missense

c.1085C>T; p.S362F; 14:37591699-37591699

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1085C>T; p.S362F; 14:37591699-37591699

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1045T>C; p.L349L; 14:37591739-37591739

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1175C>T; p.P392L; 14:37591609-37591609

 skinmalignant_melanomaSubstitution - Missense

c.650_651CC>TT; p.S217F; 14:37592133-37592134

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.70G>A; p.E24K; 14:37594903-37594903

 skinmalignant_melanomaSubstitution - Missense

c.404A>G; p.N135S; 14:37592380-37592380

 skinmalignant_melanomaSubstitution - Missense

c.75C>T; p.A25A; 14:37592709-37592709

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - coding silent

c.209A>C; p.N70T; 14:37592575-37592575

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.795C>A; p.R265R; 14:37591989-37591989

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.468C>T; p.G156G; 14:37592316-37592316

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.652A>C; p.I218L; 14:37592132-37592132

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.676G>A; p.D226N; 14:37592108-37592108

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1164G>A; p.L388L; 14:37591620-37591620

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.653T>C; p.I218T; 14:37592131-37592131

 urinary_tract; bladdercarcinomaSubstitution - Missense