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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3065

Name

HDAC1

Synonymous

histone deacetylase 1;HDAC1;histone deacetylase 1

Definition

reduced potassium dependency, yeast homolog-like 1

Position

1p34

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1335_1336delAG; p.E446fs*2; 1:32332205-32332206

 breastcarcinomaDeletion - Frameshift

c.286G>A; p.V96I; 1:32324484-32324484

 breastcarcinomaSubstitution - Missense

c.1422G>A; p.G474G; 1:32333017-32333017

 breastcarcinomaSubstitution - coding silent

c.1422-2A>T; p.?; 1:32333015-32333015

 breastcarcinomaUnknown

c.418C>T; p.H140Y; 1:32327001-32327001

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.1192G>A; p.E398K; 1:32331779-32331779

 breastcarcinomaSubstitution - Missense

c.50-2A>G; p.?; 1:32302619-32302619

 breastcarcinomaUnknown

c.966G>T; p.T322T; 1:32330895-32330895

 breastcarcinomaSubstitution - coding silent

c.1135G>T; p.V379F; 1:32331722-32331722

 breastcarcinomaSubstitution - Missense

c.1094G>A; p.R365Q; 1:32331681-32331681

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.504G>A; p.Q168Q; 1:32327545-32327545

 breastcarcinomaSubstitution - coding silent

c.1126G>A; p.A376T; 1:32331713-32331713

 breastcarcinomaSubstitution - Missense

c.1191C>T; p.D397D; 1:32331778-32331778

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.767C>T; p.A256V; 1:32330615-32330615

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1397_1399delAGG; p.E468delE; 1:32332725-32332727

 endometriumcarcinoma; endometrioid_carcinomaDeletion - In frame

c.206G>A; p.S69N; 1:32316708-32316708

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.932G>A; p.C311Y; 1:32330861-32330861

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.101G>A; p.R34Q; 1:32302672-32302672

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.240T>C; p.R80R; 1:32316742-32316742

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1360_1362delGAG; p.E455delE; 1:32332230-32332232

 endometriumcarcinoma; endometrioid_carcinomaDeletion - In frame

c.1023C>G; p.F341L; 1:32331517-32331517

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1162G>A; p.A388T; 1:32331749-32331749

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.921C>T; p.N307N; 1:32330850-32330850

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.258G>C; p.E86D; 1:32316760-32316760

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.92A>C; p.K31T; 1:32302663-32302663

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1397_1399delAGG; p.E468delE; 1:32332725-32332727

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1397_1399delAGG; p.E468delE; 1:32332725-32332727

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.1397_1399delAGG; p.E468delE; 1:32332725-32332727

 large_intestinecarcinoma; adenocarcinomaDeletion - In frame

c.1397_1399delAGG; p.E468delE; 1:32332725-32332727

 large_intestinecarcinoma; adenocarcinomaDeletion - In frame

c.540T>C; p.G180G; 1:32327581-32327581

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.844G>A; p.A282T; 1:32330773-32330773

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.74G>A; p.G25E; 1:32302645-32302645

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.74G>A; p.G25E; 1:32302645-32302645

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.232T>C; p.S78P; 1:32316734-32316734

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1192G>A; p.E398K; 1:32331779-32331779

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.199T>C; p.Y67H; 1:32316701-32316701

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.199T>C; p.Y67H; 1:32316701-32316701

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.570G>A; p.T190T; 1:32327611-32327611

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.691G>A; p.G231R; 1:32329122-32329122

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1292G>A; p.R431H; 1:32332162-32332162

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1264G>A; p.D422N; 1:32332134-32332134

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.101G>A; p.R34Q; 1:32302672-32302672

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.664T>G; p.Y222D; 1:32329095-32329095

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.813A>G; p.L271L; 1:32330661-32330661

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1381G>A; p.E461K; 1:32332709-32332709

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.183T>A; p.A61A; 1:32316685-32316685

 livercarcinomaSubstitution - coding silent

c.183T>A; p.A61A; 1:32316685-32316685

 livercarcinomaSubstitution - coding silent

c.49+1G>C; p.?; 1:32292219-32292219

 livercarcinomaUnknown

c.839-2A>G; p.?; 1:32330766-32330766

 livercarcinomaUnknown

c.229C>T; p.R77C; 1:32316731-32316731

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.229C>T; p.R77C; 1:32316731-32316731

 lungcarcinoma; bronchioloalveolar_adenocarcinomaSubstitution - Missense

c.1162G>A; p.A388T; 1:32331749-32331749

 lungcarcinoid-endocrine_tumour; atypicalSubstitution - Missense

c.1188G>C; p.E396D; 1:32331775-32331775

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.895G>T; p.G299*; 1:32330824-32330824

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1291C>T; p.R431C; 1:32332161-32332161

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.917G>T; p.R306L; 1:32330846-32330846

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.468C>T; p.I156I; 1:32327051-32327051

 NSNSSubstitution - coding silent

c.281-2A>T; p.?; 1:32324477-32324477

 oesophaguscarcinoma; adenocarcinomaUnknown

c.74G>C; p.G25A; 1:32302645-32302645

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.449T>G; p.F150C; 1:32327032-32327032

 pancreascarcinomaSubstitution - Missense

c.1372+9G>A; p.?; 1:32332251-32332251

 pancreascarcinomaUnknown

c.809G>A; p.R270Q; 1:32330657-32330657

 pancreascarcinomaSubstitution - Missense

c.162T>C; p.Y54Y; 1:32302733-32302733

 pancreascarcinomaSubstitution - coding silent

c.341C>T; p.T114I; 1:32324539-32324539

 pancreascarcinomaSubstitution - Missense

c.795C>T; p.S265S; 1:32330643-32330643

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1108C>T; p.L370F; 1:32331695-32331695

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1103A>G; p.E368G; 1:32331690-32331690

 skinmalignant_melanomaSubstitution - Missense

c.839-2_839-1insG; p.?; 1:32330766-32330767

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.750G>A; p.E250E; 1:32330598-32330598

 skinmalignant_melanomaSubstitution - coding silent

c.637-1G>A; p.?; 1:32329067-32329067

 skinmalignant_melanomaUnknown

c.1363G>A; p.E455K; 1:32332233-32332233

 skin; trunkmalignant_melanomaSubstitution - Missense

c.237C>T; p.I79I; 1:32316739-32316739

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.468C>T; p.I156I; 1:32327051-32327051

 skinmalignant_melanomaSubstitution - coding silent

c.756C>T; p.F252F; 1:32330604-32330604

 skinmalignant_melanomaSubstitution - coding silent

c.436G>A; p.E146K; 1:32327019-32327019

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.685C>T; p.R229*; 1:32329116-32329116

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.618A>G; p.P206P; 1:32327659-32327659

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.609G>T; p.E203D; 1:32327650-32327650

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.922G>A; p.V308I; 1:32330851-32330851

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1093C>T; p.R365*; 1:32331680-32331680

 thyroidcarcinoma; anaplastic_carcinomaSubstitution - Nonsense

c.943G>A; p.E315K; 1:32330872-32330872

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.943G>A; p.E315K; 1:32330872-32330872

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1090C>T; p.Q364*; 1:32331677-32331677

 urinary_tract; bladdercarcinomaSubstitution - Nonsense