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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2931

Name

GSK3A

Synonymous

glycogen synthase kinase 3 alpha;GSK3A;glycogen synthase kinase 3 alpha

Definition

GSK-3 alpha|glycogen synthase kinase-3 alpha|serine/threonine-protein kinase GSK3A

Position

19q13.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1295T>C; p.I432T; 19:42232140-42232140

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1361T>C; p.L454P; 19:42232074-42232074

 bone; ribEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.418G>T; p.E140*; 19:42240008-42240008

 breastcarcinomaSubstitution - Nonsense

c.430C>G; p.L144V; 19:42239996-42239996

 breastcarcinomaSubstitution - Missense

c.758A>G; p.D253G; 19:42234587-42234587

 breastcarcinomaSubstitution - Missense

c.1363A>C; p.T455P; 19:42232072-42232072

 breastcarcinomaSubstitution - Missense

c.710C>T; p.S237F; 19:42234635-42234635

 breastcarcinomaSubstitution - Missense

c.1043A>G; p.N348S; 19:42233165-42233165

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1250G>A; p.R417H; 19:42232531-42232531

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1250G>A; p.R417H; 19:42232531-42232531

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.850T>C; p.Y284H; 19:42234407-42234407

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1045C>A; p.P349T; 19:42233163-42233163

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.436G>A; p.A146T; 19:42239990-42239990

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.436G>A; p.A146T; 19:42239990-42239990

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.511A>G; p.N171D; 19:42236902-42236902

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.848G>A; p.R283H; 19:42234409-42234409

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1132G>A; p.A378T; 19:42232649-42232649

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.449T>C; p.V150A; 19:42239977-42239977

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1374A>G; p.S458S; 19:42232061-42232061

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1125G>T; p.E375D; 19:42232656-42232656

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.502G>T; p.D168Y; 19:42236911-42236911

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1199A>T; p.H400L; 19:42232582-42232582

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.688C>G; p.R230G; 19:42234657-42234657

 kidneyother; neoplasmSubstitution - Missense

c.1119G>A; p.P373P; 19:42232662-42232662

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1010delG; p.G337fs*11; 19:42233198-42233198

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.572T>C; p.L191P; 19:42236700-42236700

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1033C>T; p.R345*; 19:42233175-42233175

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.346G>T; p.E116*; 19:42240080-42240080

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1134G>A; p.A378A; 19:42232647-42232647

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.310G>A; p.V104I; 19:42240116-42240116

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.983A>G; p.Q328R; 19:42233305-42233305

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.561C>T; p.D187D; 19:42236711-42236711

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.635C>T; p.A212V; 19:42236637-42236637

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.364A>G; p.I122V; 19:42240062-42240062

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.436G>A; p.A146T; 19:42239990-42239990

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1395G>A; p.P465P; 19:42230851-42230851

 large_intestine; rectumNSSubstitution - coding silent

c.353C>A; p.A118D; 19:42240073-42240073

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.353C>A; p.A118D; 19:42240073-42240073

 large_intestine; coloncarcinomaSubstitution - Missense

c.353C>A; p.A118D; 19:42240073-42240073

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1378+2T>C; p.?; 19:42232055-42232055

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.814C>T; p.R272*; 19:42234443-42234443

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.397G>A; p.V133M; 19:42240029-42240029

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.397G>A; p.V133M; 19:42240029-42240029

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1199A>G; p.H400R; 19:42232582-42232582

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1200C>T; p.H400H; 19:42232581-42232581

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.848G>A; p.R283H; 19:42234409-42234409

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.388T>G; p.F130V; 19:42240038-42240038

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.388T>G; p.F130V; 19:42240038-42240038

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.244G>A; p.A82T; 19:42242222-42242222

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.727C>T; p.R243C; 19:42234618-42234618

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1191C>A; p.A397A; 19:42232590-42232590

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1097A>C; p.K366T; 19:42233111-42233111

 livercarcinomaSubstitution - Missense

c.283C>G; p.R95G; 19:42242183-42242183

 livercarcinomaSubstitution - Missense

c.283C>G; p.R95G; 19:42242183-42242183

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.784T>C; p.C262R; 19:42234561-42234561

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.579G>T; p.L193L; 19:42236693-42236693

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.809T>G; p.L270W; 19:42234448-42234448

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.562G>T; p.E188*; 19:42236710-42236710

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.688C>T; p.R230C; 19:42234657-42234657

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1199A>G; p.H400R; 19:42232582-42232582

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1200C>G; p.H400Q; 19:42232581-42232581

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1446C>T; p.S482S; 19:42230800-42230800

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.162G>A; p.G54G; 19:42242304-42242304

 ovaryother; neoplasmSubstitution - coding silent

c.366C>G; p.I122M; 19:42240060-42240060

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1134G>T; p.A378A; 19:42232647-42232647

 prostatecarcinomaSubstitution - coding silent

c.848G>A; p.R283H; 19:42234409-42234409

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1210G>T; p.D404Y; 19:42232571-42232571

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.795C>T; p.G265G; 19:42234550-42234550

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1252C>T; p.P418S; 19:42232529-42232529

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1119G>A; p.P373P; 19:42232662-42232662

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1193G>A; p.C398Y; 19:42232588-42232588

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1137C>T; p.L379L; 19:42232644-42232644

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1099-2A>G; p.?; 19:42232684-42232684

 stomachcarcinoma; adenocarcinomaUnknown

c.1088C>A; p.P363H; 19:42233120-42233120

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.729C>T; p.R243R; 19:42234616-42234616

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.319C>T; p.L107L; 19:42240107-42240107

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1111C>A; p.R371R; 19:42232670-42232670

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1111C>A; p.R371R; 19:42232670-42232670

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.462G>C; p.K154N; 19:42239964-42239964

 urinary_tract; bladdercarcinomaSubstitution - Missense