ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2771

Name

GNAI2

Synonymous

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2;GNAI2;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Definition

GTP-binding regulatory protein Gi alpha-2 chain|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-2|guanine nucleotide-binding protein G(i), alpha-2 subunit

Position

3p21.31

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.654C>T; p.G218G; 3:50256783-50256783

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.1005C>T; p.F335F; 3:50257627-50257627

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.12C>A; p.T4T; 3:50236347-50236347

 breastcarcinomaSubstitution - coding silent

c.292C>T; p.P98S; 3:50252527-50252527

 breastcarcinomaSubstitution - Missense

c.109C>A; p.L37M; 3:50236444-50236444

 breastcarcinomaSubstitution - Missense

c.801C>T; p.L267L; 3:50257014-50257014

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.511A>G; p.T171A; 3:50256238-50256238

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.412C>T; p.Q138*; 3:50253132-50253132

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.979G>A; p.A327T; 3:50257601-50257601

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.280G>A; p.D94N; 3:50252515-50252515

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.694G>T; p.D232Y; 3:50256823-50256823

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.724A>C; p.N242H; 3:50256937-50256937

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.553A>G; p.I185V; 3:50256280-50256280

 haematopoietic_and_lymphoid_tissue; soft_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.545C>T; p.T182I; 3:50256272-50256272

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.544A>G; p.T182A; 3:50256271-50256271

 haematopoietic_and_lymphoid_tissue; soft_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.136A>G; p.K46E; 3:50252117-50252117

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.465-2A>G; p.?; 3:50256190-50256190

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaUnknown

c.465-2A>G; p.?; 3:50256190-50256190

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaUnknown

c.487A>T; p.I163F; 3:50256214-50256214

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.528A>G; p.L176L; 3:50256255-50256255

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.536G>A; p.R179H; 3:50256263-50256263

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.536G>A; p.R179H; 3:50256263-50256263

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.536G>A; p.R179H; 3:50256263-50256263

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.542A>T; p.K181M; 3:50256269-50256269

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.542A>T; p.K181M; 3:50256269-50256269

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.428G>A; p.R143H; 3:50253148-50253148

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.719A>C; p.E240A; 3:50256848-50256848

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.978C>T; p.C326C; 3:50257600-50257600

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.694G>T; p.D232Y; 3:50256823-50256823

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.309C>T; p.D103D; 3:50253029-50253029

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.204G>A; p.Q68Q; 3:50252439-50252439

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.140G>A; p.S47N; 3:50252121-50252121

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.543G>A; p.K181K; 3:50256270-50256270

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.753C>T; p.F251F; 3:50256966-50256966

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.801C>T; p.L267L; 3:50257014-50257014

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.342C>A; p.A114A; 3:50253062-50253062

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.289G>A; p.D97N; 3:50252524-50252524

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.501C>T; p.D167D; 3:50256228-50256228

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.71G>T; p.R24L; 3:50236406-50236406

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.310G>A; p.A104T; 3:50253030-50253030

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.474C>T; p.N158N; 3:50256201-50256201

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.342C>T; p.A114A; 3:50253062-50253062

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.539T>C; p.V180A; 3:50256266-50256266

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.309C>T; p.D103D; 3:50253029-50253029

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.681_682insT; p.L228fs*5; 3:50256810-50256811

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.509C>T; p.P170L; 3:50256236-50256236

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.213G>A; p.A71A; 3:50252448-50252448

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.630G>T; p.K210N; 3:50256759-50256759

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.845G>A; p.S282N; 3:50257058-50257058

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.602A>G; p.D201G; 3:50256731-50256731

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1055G>A; p.C352Y; 3:50257677-50257677

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.530G>A; p.R177Q; 3:50256257-50256257

 livercarcinomaSubstitution - Missense

c.530G>A; p.R177Q; 3:50256257-50256257

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.463T>C; p.Y155H; 3:50253183-50253183

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.463T>C; p.Y155H; 3:50253183-50253183

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.790T>C; p.S264P; 3:50257003-50257003

 livercarcinomaSubstitution - Missense

c.477C>T; p.D159D; 3:50256204-50256204

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.426C>T; p.G142G; 3:50253146-50253146

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.343G>T; p.E115*; 3:50253063-50253063

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Nonsense

c.428G>A; p.R143H; 3:50253148-50253148

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.340G>A; p.A114T; 3:50253060-50253060

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.303G>A; p.A101A; 3:50252538-50252538

 prostatecarcinomaSubstitution - coding silent

c.340G>A; p.A114T; 3:50253060-50253060

 prostatecarcinomaSubstitution - Missense

c.246G>C; p.M82I; 3:50252481-50252481

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.556G>A; p.V186M; 3:50256283-50256283

 prostatecarcinomaSubstitution - Missense

c.428G>A; p.R143H; 3:50253148-50253148

 skinmalignant_melanomaSubstitution - Missense

c.243C>T; p.I81I; 3:50252478-50252478

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.185_186CC>TT; p.S62F; 3:50252420-50252421

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.933G>T; p.L311L; 3:50257555-50257555

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.545C>T; p.T182I; 3:50256272-50256272

 skinmalignant_melanomaSubstitution - Missense

c.791C>T; p.S264F; 3:50257004-50257004

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.681C>T; p.A227A; 3:50256810-50256810

 skinmalignant_melanomaSubstitution - coding silent

c.1005C>T; p.F335F; 3:50257627-50257627

 skinmalignant_melanomaSubstitution - coding silent

c.142A>T; p.T48S; 3:50252123-50252123

 skinmalignant_melanomaSubstitution - Missense

c.850C>T; p.L284L; 3:50257063-50257063

 skin; armmalignant_melanomaSubstitution - coding silent

c.488T>A; p.I163N; 3:50256215-50256215

 skinmalignant_melanomaSubstitution - Missense

c.402C>T; p.D134D; 3:50253122-50253122

 skinmalignant_melanomaSubstitution - coding silent

c.535C>T; p.R179C; 3:50256262-50256262

 skinmalignant_melanomaSubstitution - Missense

c.535C>T; p.R179C; 3:50256262-50256262

 skinmalignant_melanomaSubstitution - Missense

c.536G>A; p.R179H; 3:50256263-50256263

 skinmalignant_melanomaSubstitution - Missense

c.294C>T; p.P98P; 3:50252529-50252529

 skinmalignant_melanomaSubstitution - coding silent

c.491C>T; p.A164V; 3:50256218-50256218

 skinmalignant_melanomaSubstitution - Missense

c.530G>A; p.R177Q; 3:50256257-50256257

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.625C>T; p.R209W; 3:50256754-50256754

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.655G>A; p.V219I; 3:50256784-50256784

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.212C>T; p.A71V; 3:50252447-50252447

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1018G>A; p.V340I; 3:50257640-50257640

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.117G>T; p.L39F; 3:50236452-50236452

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.209G>A; p.R70Q; 3:50252444-50252444

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.209G>A; p.R70Q; 3:50252444-50252444

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense