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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

26585

Name

GREM1

Synonymous

gremlin 1, DAN family BMP antagonist;GREM1;gremlin 1, DAN family BMP antagonist

Definition

DAN domain family member 2|cell proliferation-inducing gene 2 protein|colorectal adenoma and carcinoma 1|cysteine knot superfamily 1, BMP antagonist 1|down-regulated in Mos-transformed cells protein|gremlin 1, cysteine knot superfamily, homolog|gremlin 1-

Position

15q13.3

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.523C>A; p.Q175K; 15:32731213-32731213

 adrenal_gland; adrenal_glandadrenal_cortical_carcinoma; functioningSubstitution - Missense

c.332G>C; p.R111P; 15:32731022-32731022

 breastcarcinomaSubstitution - Missense

c.271C>T; p.R91*; 15:32730961-32730961

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.333C>A; p.R111R; 15:32731023-32731023

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.237G>T; p.E79D; 15:32730927-32730927

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.11C>A; p.T4K; 15:32730701-32730701

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.347G>A; p.R116H; 15:32731037-32731037

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.99delC; p.P35fs*49; 15:32730789-32730789

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.346C>A; p.R116S; 15:32731036-32731036

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.461T>C; p.V154A; 15:32731151-32731151

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.240C>G; p.A80A; 15:32730930-32730930

 livercarcinomaSubstitution - coding silent

c.240C>G; p.A80A; 15:32730930-32730930

 livercarcinomaSubstitution - coding silent

c.111C>T; p.D37D; 15:32730801-32730801

 livercarcinomaSubstitution - coding silent

c.111C>T; p.D37D; 15:32730801-32730801

 livercarcinomaSubstitution - coding silent

c.88C>G; p.Q30E; 15:32730778-32730778

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.87C>T; p.S29S; 15:32730777-32730777

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.322T>A; p.C108S; 15:32731012-32731012

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.186A>T; p.Q62H; 15:32730876-32730876

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.67G>A; p.E23K; 15:32730757-32730757

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.438C>A; p.P146P; 15:32731128-32731128

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.492T>A; p.P164P; 15:32731182-32731182

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.394C>T; p.R132W; 15:32731084-32731084

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.93T>G; p.G31G; 15:32730783-32730783

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.395G>A; p.R132Q; 15:32731085-32731085

 prostatecarcinomaSubstitution - Missense

c.72G>A; p.G24G; 15:32730762-32730762

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.103C>T; p.P35S; 15:32730793-32730793

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.187G>A; p.G63R; 15:32730877-32730877

 skinmalignant_melanomaSubstitution - Missense

c.78G>A; p.K26K; 15:32730768-32730768

 skinmalignant_melanomaSubstitution - coding silent

c.211G>A; p.E71K; 15:32730901-32730901

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.168G>A; p.R56R; 15:32730858-32730858

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.410C>T; p.S137F; 15:32731100-32731100

 skinmalignant_melanomaSubstitution - Missense

c.410C>T; p.S137F; 15:32731100-32731100

 skin; solemalignant_melanoma; acral_lentiginousSubstitution - Missense

c.490C>T; p.P164S; 15:32731180-32731180

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.377A>T; p.Y126F; 15:32731067-32731067

 thyroidother; neoplasmSubstitution - Missense

c.54G>T; p.L18L; 15:32730744-32730744

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.54G>T; p.L18L; 15:32730744-32730744

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.95C>T; p.A32V; 15:32730785-32730785

 urinary_tract; bladdercarcinomaSubstitution - Missense