ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

25937

Name

WWTR1

Synonymous

WW domain containing transcription regulator 1;WWTR1;WW domain containing transcription regulator 1

Definition

WW domain-containing transcription regulator protein 1|transcriptional co-activator with PDZ-binding motif|transcriptional coactivator with PDZ-binding motif

Position

3q23-q24

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1052A>G; p.N351S; 3:149520956-149520956

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.962A>G; p.Y321C; 3:149526069-149526069

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.826C>G; p.Q276E; 3:149527915-149527915

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.576T>C; p.N192N; 3:149542530-149542530

 bone; tibiaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.864G>C; p.M288I; 3:149527877-149527877

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.895T>G; p.F299V; 3:149527846-149527846

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.895T>G; p.F299V; 3:149527846-149527846

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.895T>G; p.F299V; 3:149527846-149527846

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.909G>T; p.G303G; 3:149526122-149526122

 breastcarcinomaSubstitution - coding silent

c.189C>G; p.R63R; 3:149657118-149657118

 breastcarcinomaSubstitution - coding silent

c.235G>T; p.A79S; 3:149657072-149657072

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1050C>A; p.I350I; 3:149520958-149520958

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.981G>A; p.P327P; 3:149526050-149526050

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.671C>T; p.A224V; 3:149542435-149542435

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.671C>T; p.A224V; 3:149542435-149542435

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.706C>T; p.R236W; 3:149542400-149542400

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.268T>C; p.S90P; 3:149657039-149657039

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.742C>T; p.R248*; 3:149542364-149542364

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.742C>T; p.R248*; 3:149542364-149542364

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1067G>A; p.R356H; 3:149520941-149520941

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.1067G>A; p.R356H; 3:149520941-149520941

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.1067G>A; p.R356H; 3:149520941-149520941

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.265T>A; p.S89T; 3:149657042-149657042

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.920C>T; p.S307L; 3:149526111-149526111

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1105G>A; p.V369I; 3:149520903-149520903

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.63G>A; p.T21T; 3:149657244-149657244

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.57C>T; p.H19H; 3:149657250-149657250

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1026C>G; p.N342K; 3:149520982-149520982

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.446T>A; p.I149N; 3:149572986-149572986

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.383delC; p.P128fs*5; 3:149656924-149656924

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.872T>C; p.I291T; 3:149527869-149527869

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.221C>A; p.P74Q; 3:149657086-149657086

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.699_700insCAG; p.Q233_K234insQ; 3:149542406-149542407

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - In frame

c.742C>T; p.R248*; 3:149542364-149542364

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.742C>T; p.R248*; 3:149542364-149542364

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.742C>T; p.R248*; 3:149542364-149542364

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.896T>C; p.F299S; 3:149527845-149527845

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.896T>C; p.F299S; 3:149527845-149527845

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.895T>C; p.F299L; 3:149527846-149527846

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.895T>C; p.F299L; 3:149527846-149527846

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.444A>C; p.K148N; 3:149572988-149572988

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.432-8T>G; p.?; 3:149573008-149573008

 livercarcinomaUnknown

c.132G>T; p.R44R; 3:149657175-149657175

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.605G>T; p.S202I; 3:149542501-149542501

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.367G>C; p.E123Q; 3:149656940-149656940

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.474G>C; p.A158A; 3:149572958-149572958

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.817G>T; p.A273S; 3:149527924-149527924

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.131G>T; p.R44L; 3:149657176-149657176

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.4A>C; p.N2H; 3:149657303-149657303

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.801G>T; p.M267I; 3:149527940-149527940

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.885C>T; p.S295S; 3:149527856-149527856

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.916C>T; p.H306Y; 3:149526115-149526115

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.864G>A; p.M288I; 3:149527877-149527877

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.481C>G; p.Q161E; 3:149572951-149572951

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.484C>G; p.P162A; 3:149572948-149572948

 ovaryother; neoplasmSubstitution - Missense

c.272C>A; p.P91H; 3:149657035-149657035

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.516C>T; p.V172V; 3:149572916-149572916

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1104C>T; p.N368N; 3:149520904-149520904

 prostatecarcinomaSubstitution - coding silent

c.555C>T; p.S185S; 3:149572877-149572877

 skinmalignant_melanomaSubstitution - coding silent

c.447C>T; p.I149I; 3:149572985-149572985

 skinmalignant_melanomaSubstitution - coding silent

c.526_527CC>TT; p.P176L; 3:149572905-149572906

 skinmalignant_melanomaSubstitution - Missense

c.240G>A; p.G80G; 3:149657067-149657067

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.12C>T; p.A4A; 3:149657295-149657295

 skinmalignant_melanomaSubstitution - coding silent

c.916C>T; p.H306Y; 3:149526115-149526115

 skinmalignant_melanomaSubstitution - Missense

c.426C>T; p.F142F; 3:149656881-149656881

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.649G>A; p.G217R; 3:149542457-149542457

 skinmalignant_melanomaSubstitution - Missense

c.160A>G; p.K54E; 3:149657147-149657147

 skinmalignant_melanomaSubstitution - Missense

c.864G>A; p.M288I; 3:149527877-149527877

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1057C>T; p.Q353*; 3:149520951-149520951

 skin; abdomenmalignant_melanomaSubstitution - Nonsense

c.889G>A; p.D297N; 3:149527852-149527852

 skinmalignant_melanomaSubstitution - Missense

c.504C>T; p.L168L; 3:149572928-149572928

 skinmalignant_melanomaSubstitution - coding silent

c.532C>T; p.P178S; 3:149572900-149572900

 skinmalignant_melanomaSubstitution - Missense

c.514G>A; p.V172I; 3:149572918-149572918

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1059A>G; p.Q353Q; 3:149520949-149520949

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.383delC; p.P128fs*5; 3:149656924-149656924

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.697_699delCAG; p.Q233delQ; 3:149542407-149542409

 stomachcarcinoma; diffuse_adenocarcinomaDeletion - In frame

c.235G>T; p.A79S; 3:149657072-149657072

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.235G>T; p.A79S; 3:149657072-149657072

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.235G>T; p.A79S; 3:149657072-149657072

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.235G>T; p.A79S; 3:149657072-149657072

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.235G>T; p.A79S; 3:149657072-149657072

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.1200_1201insTTAA; p.*401fs*>2; 3:149520807-149520808

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.699G>C; p.Q233H; 3:149542407-149542407

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.864G>A; p.M288I; 3:149527877-149527877

 urinary_tract; bladdercarcinomaSubstitution - Missense