Entrez Gene

Basic Information
Gene ID	25849
Name	PARM1
Synonymous	prostate androgen-regulated mucin-like protein 1;PARM1;prostate androgen-regulated mucin-like protein 1
Definition	WSC4, cell wall integrity and stress response component 4 homolog\|castration-induced prostatic apoptosis-related protein 1\|prostatic androgen-regulated mucin-like protein 1\|prostatic androgen-repressed message 1\|prostatic androgen-repressed message-1
Position	4q13.3-q21.3
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.363G>A; p.T121T; 4:75012744-75012744	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.45A>T; p.G15G; 4:75012426-75012426	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.96G>A; p.P32P; 4:75012477-75012477	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.660A>C; p.T220T; 4:75013041-75013041	breast	carcinoma	Substitution - coding silent
c.550A>C; p.T184P; 4:75012931-75012931	breast	carcinoma	Substitution - Missense
c.576A>C; p.A192A; 4:75012957-75012957	breast	carcinoma	Substitution - coding silent
c.721A>C; p.T241P; 4:75013102-75013102	breast	carcinoma	Substitution - Missense
c.206C>G; p.T69R; 4:75012587-75012587	central_nervous_system; midbrain	glioma; oligoastrocytoma_Grade_III	Substitution - Missense
c.454C>G; p.Q152E; 4:75012835-75012835	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.424G>A; p.A142T; 4:75012805-75012805	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.769+1G>A; p.?; 4:75013151-75013151	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.403G>A; p.A135T; 4:75012784-75012784	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.285G>A; p.S95S; 4:75012666-75012666	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.63G>T; p.L21L; 4:75012444-75012444	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.237G>T; p.K79N; 4:75012618-75012618	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.645A>G; p.V215V; 4:75013026-75013026	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.96G>C; p.P32P; 4:75012477-75012477	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.574G>A; p.A192T; 4:75012955-75012955	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.285G>T; p.S95S; 4:75012666-75012666	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.68C>T; p.T23I; 4:75012449-75012449	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.95C>T; p.P32L; 4:75012476-75012476	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.128C>T; p.T43I; 4:75012509-75012509	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.424G>A; p.A142T; 4:75012805-75012805	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.115A>G; p.T39A; 4:75012496-75012496	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.150T>G; p.D50E; 4:75012531-75012531	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.225T>G; p.S75S; 4:75012606-75012606	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.690G>T; p.M230I; 4:75013071-75013071	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.155A>G; p.D52G; 4:75012536-75012536	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.767C>A; p.S256*; 4:75013148-75013148	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.26T>G; p.L9R; 4:74933353-74933353	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.96G>A; p.P32P; 4:75012477-75012477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.248T>C; p.I83T; 4:75012629-75012629	liver	carcinoma	Substitution - Missense
c.424G>A; p.A142T; 4:75012805-75012805	liver	carcinoma	Substitution - Missense
c.424G>A; p.A142T; 4:75012805-75012805	liver	carcinoma	Substitution - Missense
c.629C>A; p.A210D; 4:75013010-75013010	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.588G>A; p.P196P; 4:75012969-75012969	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.225T>C; p.S75S; 4:75012606-75012606	liver	carcinoma	Substitution - coding silent
c.225T>C; p.S75S; 4:75012606-75012606	liver	carcinoma	Substitution - coding silent
c.317C>T; p.P106L; 4:75012698-75012698	liver	carcinoma	Substitution - Missense
c.317C>T; p.P106L; 4:75012698-75012698	liver	carcinoma	Substitution - Missense
c.568C>T; p.P190S; 4:75012949-75012949	liver	carcinoma	Substitution - Missense
c.759A>G; p.A253A; 4:75013140-75013140	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.494C>A; p.P165Q; 4:75012875-75012875	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.307G>A; p.D103N; 4:75012688-75012688	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.76C>G; p.P26A; 4:75012457-75012457	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.63G>T; p.L21L; 4:75012444-75012444	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.310C>G; p.P104A; 4:75012691-75012691	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.889G>A; p.G297R; 4:75046203-75046203	pleura	pulmonary_blastoma	Substitution - Missense
c.366G>A; p.L122L; 4:75012747-75012747	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.349C>T; p.H117Y; 4:75012730-75012730	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.267G>A; p.E89E; 4:75012648-75012648	skin	malignant_melanoma	Substitution - coding silent
c.370G>A; p.E124K; 4:75012751-75012751	skin	malignant_melanoma	Substitution - Missense
c.735G>A; p.V245V; 4:75013116-75013116	skin	malignant_melanoma	Substitution - coding silent
c.47G>A; p.W16*; 4:75012428-75012428	skin	malignant_melanoma	Substitution - Nonsense
c.343G>A; p.G115R; 4:75012724-75012724	skin	malignant_melanoma	Substitution - Missense
c.515C>T; p.S172F; 4:75012896-75012896	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515C>T; p.S172F; 4:75012896-75012896	skin	malignant_melanoma	Substitution - Missense
c.501G>A; p.E167E; 4:75012882-75012882	skin	malignant_melanoma	Substitution - coding silent
c.383G>A; p.G128D; 4:75012764-75012764	skin	malignant_melanoma	Substitution - Missense
c.709G>A; p.E237K; 4:75013090-75013090	skin	malignant_melanoma	Substitution - Missense
c.284C>T; p.S95L; 4:75012665-75012665	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.284C>T; p.S95L; 4:75012665-75012665	skin	malignant_melanoma	Substitution - Missense
c.284C>T; p.S95L; 4:75012665-75012665	skin	malignant_melanoma	Substitution - Missense
c.89C>T; p.S30F; 4:75012470-75012470	skin	malignant_melanoma	Substitution - Missense
c.922G>A; p.D308N; 4:75046236-75046236	skin	malignant_melanoma	Substitution - Missense
c.436_437CC>TT; p.P146F; 4:75012817-75012818	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.314C>T; p.S105L; 4:75012695-75012695	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.199C>T; p.P67S; 4:75012580-75012580	skin	malignant_melanoma	Substitution - Missense
c.584C>T; p.S195F; 4:75012965-75012965	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.199C>T; p.P67S; 4:75012580-75012580	skin	malignant_melanoma	Substitution - Missense
c.657A>T; p.K219N; 4:75013038-75013038	skin	malignant_melanoma	Substitution - Missense
c.580G>A; p.E194K; 4:75012961-75012961	skin	malignant_melanoma	Substitution - Missense
c.329C>T; p.S110L; 4:75012710-75012710	skin	malignant_melanoma	Substitution - Missense
c.71C>T; p.S24L; 4:75012452-75012452	skin	malignant_melanoma	Substitution - Missense
c.745G>A; p.E249K; 4:75013126-75013126	skin	malignant_melanoma	Substitution - Missense
c.745G>A; p.E249K; 4:75013126-75013126	skin	malignant_melanoma	Substitution - Missense
c.493C>T; p.P165S; 4:75012874-75012874	skin	malignant_melanoma	Substitution - Missense
c.476C>T; p.S159L; 4:75012857-75012857	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.363G>A; p.T121T; 4:75012744-75012744	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.182A>G; p.H61R; 4:75012563-75012563	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.851A>T; p.H284L; 4:75046165-75046165	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.376A>C; p.S126R; 4:75012757-75012757	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.215C>A; p.A72D; 4:75012596-75012596	thyroid	other; neoplasm	Substitution - Missense
c.320C>T; p.S107F; 4:75012701-75012701	thyroid	other; neoplasm	Substitution - Missense
c.319T>G; p.S107A; 4:75012700-75012700	thyroid	other; neoplasm	Substitution - Missense
c.198C>A; p.L66L; 4:75012579-75012579	thyroid	other; neoplasm	Substitution - coding silent
c.470C>T; p.S157L; 4:75012851-75012851	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.470C>T; p.S157L; 4:75012851-75012851	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.645A>G; p.V215V; 4:75013026-75013026	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.126G>T; p.W42C; 4:75012507-75012507	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

Bioinformatics and cancer genomics links

Bioinformatics centers

Bioinformatics centers

Welcome to Bioinfo-MinZhao!