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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

23373

Name

CRTC1

Synonymous

CREB regulated transcription coactivator 1;CRTC1;CREB regulated transcription coactivator 1

Definition

CREB-regulated transcription coactivator 1|mucoepidermoid carcinoma translocated protein 1|transducer of regulated cAMP response element-binding protein (CREB) 1

Position

19p13.11

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1036C>G; p.L346V; 19:18768509-18768509

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.1747G>A; p.G583R; 19:18777224-18777224

 breastcarcinomaSubstitution - Missense

c.1596G>A; p.A532A; 19:18775724-18775724

 breastcarcinomaSubstitution - coding silent

c.1713_1714insC; p.S572fs*4; 19:18777190-18777191

 breastcarcinoma; ductal_carcinomaInsertion - Frameshift

c.1846C>A; p.P616T; 19:18777323-18777323

 central_nervous_system; braingliomaSubstitution - Missense

c.879C>T; p.A293A; 19:18760221-18760221

 central_nervous_system; braingliomaSubstitution - coding silent

c.834C>T; p.T278T; 19:18760176-18760176

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1281G>C; p.E427D; 19:18768754-18768754

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.570G>T; p.E190D; 19:18753531-18753531

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1431T>G; p.T477T; 19:18774905-18774905

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.711C>T; p.P237P; 19:18760053-18760053

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.389G>T; p.S130I; 19:18747060-18747060

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1416C>T; p.S472S; 19:18771537-18771537

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1358C>A; p.S453Y; 19:18771479-18771479

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1314C>T; p.I438I; 19:18768787-18768787

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.334G>A; p.G112S; 19:18745913-18745913

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1539C>T; p.N513N; 19:18775667-18775667

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1726G>T; p.E576*; 19:18777203-18777203

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1888C>G; p.R630G; 19:18777365-18777365

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.1805T>C; p.I602T; 19:18777282-18777282

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.626C>T; p.T209M; 19:18759552-18759552

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.1870G>C; p.A624P; 19:18777347-18777347

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.539-2A>C; p.?; 19:18753498-18753498

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.539-2A>C; p.?; 19:18753498-18753498

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.539-2A>C; p.?; 19:18753498-18753498

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.539-1G>C; p.?; 19:18753499-18753499

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaUnknown

c.1898G>C; p.R633P; 19:18777375-18777375

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.918C>G; p.H306Q; 19:18765435-18765435

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.1609C>A; p.L537I; 19:18775737-18775737

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.265C>T; p.L89L; 19:18745844-18745844

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.959C>T; p.A320V; 19:18765476-18765476

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1571G>C; p.G524A; 19:18775699-18775699

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1571G>C; p.G524A; 19:18775699-18775699

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1571G>C; p.G524A; 19:18775699-18775699

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.8C>T; p.T3I; 19:18683710-18683710

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1831C>T; p.H611Y; 19:18777308-18777308

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1639T>C; p.S547P; 19:18775767-18775767

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1444A>G; p.S482G; 19:18774918-18774918

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.224C>T; p.T75I; 19:18743007-18743007

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.832A>G; p.T278A; 19:18760174-18760174

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.426G>A; p.A142A; 19:18747097-18747097

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1091C>T; p.P364L; 19:18768564-18768564

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.492G>A; p.Q164Q; 19:18749829-18749829

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1445G>A; p.S482N; 19:18774919-18774919

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.349C>T; p.R117W; 19:18745928-18745928

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.595C>A; p.L199I; 19:18753556-18753556

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1706_1707delCC; p.P571fs*4; 19:18777183-18777184

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1270_1271insC; p.E427fs*24; 19:18768743-18768744

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.1270_1271insC; p.E427fs*24; 19:18768743-18768744

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.1270_1271insC; p.E427fs*24; 19:18768743-18768744

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.936delC; p.L314fs*3; 19:18765453-18765453

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.991C>T; p.P331S; 19:18765508-18765508

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1370A>G; p.Q457R; 19:18771491-18771491

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1204G>A; p.A402T; 19:18768677-18768677

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.543A>G; p.L181L; 19:18753504-18753504

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.322C>T; p.R108C; 19:18745901-18745901

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1343G>A; p.R448H; 19:18771464-18771464

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.483G>A; p.T161T; 19:18749820-18749820

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1511A>G; p.Q504R; 19:18774985-18774985

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.690A>C; p.E230D; 19:18760032-18760032

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1271delC; p.P426fs*85; 19:18768744-18768744

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1262T>G; p.L421R; 19:18768735-18768735

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1752C>T; p.V584V; 19:18777229-18777229

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1888C>T; p.R630W; 19:18777365-18777365

 large_intestine; coloncarcinomaSubstitution - Missense

c.1888C>T; p.R630W; 19:18777365-18777365

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1235C>T; p.P412L; 19:18768708-18768708

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.726_727insG; p.S245fs*206; 19:18760068-18760069

 large_intestinecarcinoma; adenocarcinomaInsertion - Frameshift

c.727delG; p.S245fs*5; 19:18760069-18760069

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1569G>T; p.P523P; 19:18775697-18775697

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.609A>G; p.A203A; 19:18753570-18753570

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1714A>T; p.S572C; 19:18777191-18777191

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1862C>T; p.A621V; 19:18777339-18777339

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.981C>G; p.P327P; 19:18765498-18765498

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1365C>T; p.A455A; 19:18771486-18771486

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1416_1421delCTCCCC; p.S472_P474>R; 19:18771537-18771542

 lungcarcinoma; non_small_cell_carcinomaComplex - deletion inframe

c.644_645CC>TT; p.S215F; 19:18759570-18759571

 NSmalignant_melanomaSubstitution - Missense

c.1458C>T; p.D486D; 19:18774932-18774932

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.1569G>A; p.P523P; 19:18775697-18775697

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.965G>A; p.R322H; 19:18765482-18765482

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.330G>A; p.R110R; 19:18745909-18745909

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1641G>A; p.S547S; 19:18775769-18775769

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1491G>C; p.Q497H; 19:18774965-18774965

 pancreascarcinomaSubstitution - Missense

c.1706delC; p.S572fs*6; 19:18777183-18777183

 pancreascarcinoma; acinar_carcinomaDeletion - Frameshift

c.1399G>C; p.G467R; 19:18771520-18771520

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.338C>T; p.S113F; 19:18745917-18745917

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.1261C>T; p.L421F; 19:18768734-18768734

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.164C>T; p.P55L; 19:18742947-18742947

 skinmalignant_melanomaSubstitution - Missense

c.248C>T; p.P83L; 19:18745827-18745827

 skinmalignant_melanomaSubstitution - Missense

c.945C>T; p.S315S; 19:18765462-18765462

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1569G>T; p.P523P; 19:18775697-18775697

 skinmalignant_melanomaSubstitution - coding silent

c.891G>A; p.M297I; 19:18765408-18765408

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1461G>A; p.A487A; 19:18774935-18774935

 skinmalignant_melanomaSubstitution - coding silent

c.1788C>T; p.P596P; 19:18777265-18777265

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1787C>T; p.P596L; 19:18777264-18777264

 skinmalignant_melanomaSubstitution - Missense

c.1375C>T; p.P459S; 19:18771496-18771496

 skinmalignant_melanomaSubstitution - Missense

c.243G>A; p.Q81Q; 19:18743026-18743026

 skinmalignant_melanomaSubstitution - coding silent

c.1320+1G>A; p.?; 19:18768794-18768794

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.763C>T; p.P255S; 19:18760105-18760105

 skinmalignant_melanomaSubstitution - Missense

c.709C>T; p.P237S; 19:18760051-18760051

 skinmalignant_melanomaSubstitution - Missense

c.781C>T; p.P261S; 19:18760123-18760123

 skinmalignant_melanomaSubstitution - Missense

c.191C>T; p.S64F; 19:18742974-18742974

 skinmalignant_melanomaSubstitution - Missense

c.1719C>T; p.L573L; 19:18777196-18777196

 skinmalignant_melanomaSubstitution - coding silent

c.1767C>T; p.F589F; 19:18777244-18777244

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1298C>T; p.S433L; 19:18768771-18768771

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1542C>T; p.A514A; 19:18775670-18775670

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.308G>T; p.R103M; 19:18745887-18745887

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.915G>A; p.Q305Q; 19:18765432-18765432

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1641G>A; p.S547S; 19:18775769-18775769

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.940C>G; p.L314V; 19:18765457-18765457

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1271_1272insC; p.E427fs*24; 19:18768744-18768745

 stomachcarcinoma; intestinal_adenocarcinomaInsertion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.1706delC; p.S572fs*6; 19:18777183-18777183

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.902G>A; p.G301D; 19:18765419-18765419

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.886+1G>A; p.?; 19:18760229-18760229

 stomachcarcinoma; adenocarcinomaUnknown

c.674C>T; p.P225L; 19:18760016-18760016

 thyroidcarcinomaSubstitution - Missense

c.843C>A; p.L281L; 19:18760185-18760185

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.843C>A; p.L281L; 19:18760185-18760185

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.966T>C; p.R322R; 19:18765483-18765483

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.966T>C; p.R322R; 19:18765483-18765483

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.531G>T; p.Q177H; 19:18749868-18749868

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.531G>T; p.Q177H; 19:18749868-18749868

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.977C>T; p.S326L; 19:18765494-18765494

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1036C>T; p.L346L; 19:18768509-18768509

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.1036C>T; p.L346L; 19:18768509-18768509

 urinary_tract; bladdercarcinomaSubstitution - coding silent