ONGene
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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2308

Name

FOXO1

Synonymous

forkhead box O1;FOXO1;forkhead box O1

Definition

forkhead box protein O1|forkhead box protein O1A|forkhead, Drosophila, homolog of, in rhabdomyosarcoma

Position

13q14.1

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1340C>T; p.S447L; 13:40560151-40560151

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.947G>A; p.R316Q; 13:40560544-40560544

 breastcarcinomaSubstitution - Missense

c.878C>A; p.S293Y; 13:40560613-40560613

 breastcarcinomaSubstitution - Missense

c.1280G>T; p.G427V; 13:40560211-40560211

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.996G>C; p.M332I; 13:40560495-40560495

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1649C>T; p.S550L; 13:40559842-40559842

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.800G>A; p.R267Q; 13:40560691-40560691

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1373C>T; p.A458V; 13:40560118-40560118

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.640C>T; p.R214C; 13:40560851-40560851

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1550_1552delTGA; p.M517delM; 13:40559939-40559941

 endometriumcarcinoma; endometrioid_carcinomaDeletion - In frame

c.1763G>A; p.G588D; 13:40559728-40559728

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1825C>T; p.R609C; 13:40559666-40559666

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.940C>T; p.R314C; 13:40560551-40560551

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1170G>A; p.S390S; 13:40560321-40560321

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1222G>A; p.A408T; 13:40560269-40560269

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1120C>A; p.L374I; 13:40560371-40560371

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1545A>C; p.K515N; 13:40559946-40559946

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.674G>A; p.R225H; 13:40560817-40560817

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.674G>A; p.R225H; 13:40560817-40560817

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.648T>A; p.N216K; 13:40560843-40560843

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.69C>T; p.C23C; 13:40666144-40666144

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - coding silent

c.567G>A; p.W189*; 13:40665646-40665646

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Nonsense

c.28A>G; p.I10V; 13:40666185-40666185

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.1A>G; p.M1V; 13:40666212-40666212

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.56G>C; p.R19P; 13:40666157-40666157

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.608G>A; p.S203N; 13:40665605-40665605

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.70A>G; p.T24A; 13:40666143-40666143

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.579C>A; p.S193R; 13:40665634-40665634

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.1A>T; p.M1L; 13:40666212-40666212

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.64T>C; p.S22P; 13:40666149-40666149

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.64T>C; p.S22P; 13:40666149-40666149

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.71C>T; p.T24I; 13:40666142-40666142

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.71C>T; p.T24I; 13:40666142-40666142

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.71C>T; p.T24I; 13:40666142-40666142

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.224G>C; p.S75T; 13:40665989-40665989

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.61C>T; p.R21C; 13:40666152-40666152

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.1566T>C; p.H522H; 13:40559925-40559925

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.976G>C; p.G326R; 13:40560515-40560515

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.119C>T; p.S40F; 13:40666094-40666094

 kidneyother; neoplasmSubstitution - Missense

c.1736C>A; p.S579Y; 13:40559755-40559755

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.984C>G; p.L328L; 13:40560507-40560507

 kidneyother; neoplasmSubstitution - coding silent

c.562G>A; p.E188K; 13:40665651-40665651

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1609C>T; p.R537C; 13:40559882-40559882

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1721C>A; p.A574D; 13:40559770-40559770

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.925A>G; p.N309D; 13:40560566-40560566

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.925A>G; p.N309D; 13:40560566-40560566

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.641G>A; p.R214H; 13:40560850-40560850

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1269delA; p.K423fs*9; 13:40560222-40560222

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.513G>A; p.K171K; 13:40665700-40665700

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1657A>G; p.N553D; 13:40559834-40559834

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1105G>A; p.E369K; 13:40560386-40560386

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.947G>A; p.R316Q; 13:40560544-40560544

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.836C>T; p.S279F; 13:40560655-40560655

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.738C>T; p.S246S; 13:40560753-40560753

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.738C>T; p.S246S; 13:40560753-40560753

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1223C>T; p.A408V; 13:40560268-40560268

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.426T>C; p.A142A; 13:40665787-40665787

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.940C>T; p.R314C; 13:40560551-40560551

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.591C>G; p.F197L; 13:40665622-40665622

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1325T>G; p.L442R; 13:40560166-40560166

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1374G>A; p.A458A; 13:40560117-40560117

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.630+6T>G; p.?; 13:40665577-40665577

 livercarcinomaUnknown

c.96T>A; p.F32L; 13:40666117-40666117

 livercarcinomaSubstitution - Missense

c.96T>A; p.F32L; 13:40666117-40666117

 livercarcinomaSubstitution - Missense

c.1275A>G; p.T425T; 13:40560216-40560216

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.751A>C; p.R251R; 13:40560740-40560740

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.774C>T; p.D258D; 13:40560717-40560717

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1770G>T; p.M590I; 13:40559721-40559721

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1337A>C; p.K446T; 13:40560154-40560154

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1328A>G; p.Q443R; 13:40560163-40560163

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1649C>G; p.S550W; 13:40559842-40559842

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.929G>T; p.W310L; 13:40560562-40560562

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1360C>T; p.Q454*; 13:40560131-40560131

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1595C>A; p.S532Y; 13:40559896-40559896

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1866C>G; p.L622L; 13:40559625-40559625

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1145C>T; p.S382L; 13:40560346-40560346

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1056C>T; p.A352A; 13:40560435-40560435

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1684G>A; p.V562I; 13:40559807-40559807

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.56G>A; p.R19Q; 13:40666157-40666157

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1028T>A; p.V343E; 13:40560463-40560463

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1604A>C; p.N535T; 13:40559887-40559887

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1386G>C; p.L462F; 13:40560105-40560105

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1485C>T; p.N495N; 13:40560006-40560006

 ovaryother; neoplasmSubstitution - coding silent

c.544A>G; p.T182A; 13:40665669-40665669

 ovaryother; neoplasmSubstitution - Missense

c.869C>A; p.S290*; 13:40560622-40560622

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.1649C>T; p.S550L; 13:40559842-40559842

 skinmalignant_melanomaSubstitution - Missense

c.1080C>T; p.P360P; 13:40560411-40560411

 skinmalignant_melanomaSubstitution - coding silent

c.967A>G; p.T323A; 13:40560524-40560524

 skinmalignant_melanomaSubstitution - Missense

c.1739C>T; p.S580F; 13:40559752-40559752

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1217C>T; p.S406L; 13:40560274-40560274

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.943_944CC>TT; p.P315F; 13:40560547-40560548

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1344T>G; p.S448R; 13:40560147-40560147

 skinmalignant_melanomaSubstitution - Missense

c.805C>T; p.R269*; 13:40560686-40560686

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1143C>T; p.L381L; 13:40560348-40560348

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1736_1737CC>TT; p.S579F; 13:40559754-40559755

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.940C>T; p.R314C; 13:40560551-40560551

 skinmalignant_melanomaSubstitution - Missense

c.1905G>A; p.V635V; 13:40559586-40559586

 skinmalignant_melanomaSubstitution - coding silent

c.990C>T; p.P330P; 13:40560501-40560501

 skinmalignant_melanomaSubstitution - coding silent

c.1556C>T; p.P519L; 13:40559935-40559935

 skinmalignant_melanomaSubstitution - Missense

c.1218G>A; p.S406S; 13:40560273-40560273

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1223C>T; p.A408V; 13:40560268-40560268

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1506G>A; p.S502S; 13:40559985-40559985

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.779A>G; p.N260S; 13:40560712-40560712

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1380A>G; p.G460G; 13:40560111-40560111

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1493T>C; p.M498T; 13:40559998-40559998

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.673C>T; p.R225C; 13:40560818-40560818

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1374G>A; p.A458A; 13:40560117-40560117

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1374G>A; p.A458A; 13:40560117-40560117

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1416C>G; p.P472P; 13:40560075-40560075

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1416C>G; p.P472P; 13:40560075-40560075

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.1073C>T; p.T358I; 13:40560418-40560418

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.926A>G; p.N309S; 13:40560565-40560565

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.926A>G; p.N309S; 13:40560565-40560565

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1241T>C; p.L414S; 13:40560250-40560250

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1941A>G; p.T647T; 13:40559550-40559550

 urinary_tract; bladdercarcinomaSubstitution - coding silent