Entrez Gene

Basic Information
Gene ID	2305
Name	FOXM1
Synonymous	forkhead box M1;FOXM1;forkhead box M1
Definition	Forkhead, drosophila, homolog-like 16\|HNF-3/fork-head homolog 11\|M-phase phosphoprotein 2\|MPM-2 reactive phosphoprotein 2\|forkhead box protein M1\|forkhead-related protein FKHL16\|hepatocyte nuclear factor 3 forkhead homolog 11\|transcription factor Trident\|
Position	12p13
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.1321C>A; p.L441M; 12:2861358-2861358	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.208A>G; p.M70V; 12:2874271-2874271	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2328C>T; p.I776I; 12:2858716-2858716	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2330G>A; p.S777N; 12:2858714-2858714	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2123T>C; p.L708P; 12:2858921-2858921	bone; femur	chondrosarcoma	Substitution - Missense
c.2122_2123insC; p.L708fs*2; 12:2858921-2858922	breast	carcinoma	Insertion - Frameshift
c.361C>A; p.L121I; 12:2874118-2874118	breast	carcinoma	Substitution - Missense
c.1667G>T; p.S556I; 12:2859377-2859377	breast	carcinoma	Substitution - Missense
c.490C>T; p.R164W; 12:2873989-2873989	breast	carcinoma	Substitution - Missense
c.2313G>C; p.K771N; 12:2858731-2858731	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.705G>A; p.E235E; 12:2868704-2868704	breast	carcinoma	Substitution - coding silent
c.1976C>T; p.P659L; 12:2859068-2859068	breast	carcinoma	Substitution - Missense
c.2041T>C; p.S681P; 12:2859003-2859003	breast	carcinoma	Substitution - Missense
c.2041T>C; p.S681P; 12:2859003-2859003	breast	carcinoma	Substitution - Missense
c.609G>T; p.E203D; 12:2872141-2872141	breast	carcinoma	Substitution - Missense
c.799G>C; p.E267Q; 12:2868610-2868610	breast	carcinoma	Substitution - Missense
c.1229_1231delTTG; p.L410_A411>P; 12:2864355-2864357	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Complex - deletion inframe
c.1552G>A; p.E518K; 12:2859492-2859492	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.876C>T; p.H292H; 12:2866492-2866492	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.853_855delATC; p.I285delI; 12:2866513-2866515	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - In frame
c.1995G>A; p.T665T; 12:2859049-2859049	central_nervous_system; brain	glioma	Substitution - coding silent
c.863A>G; p.N288S; 12:2866505-2866505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1928C>T; p.T643M; 12:2859116-2859116	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1788G>A; p.P596P; 12:2859256-2859256	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1035G>A; p.P345P; 12:2864738-2864738	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.454C>A; p.L152I; 12:2874025-2874025	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1464T>G; p.F488L; 12:2859580-2859580	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1137A>G; p.V379V; 12:2864449-2864449	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2254G>A; p.A752T; 12:2858790-2858790	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1643C>A; p.T548N; 12:2859401-2859401	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.259A>T; p.I87F; 12:2874220-2874220	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.680C>T; p.A227V; 12:2868729-2868729	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2284C>A; p.L762M; 12:2858760-2858760	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2284C>A; p.L762M; 12:2858760-2858760	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2284C>A; p.L762M; 12:2858760-2858760	large_intestine; colon	carcinoma	Substitution - Missense
c.2284C>A; p.L762M; 12:2858760-2858760	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.480C>T; p.C160C; 12:2873999-2873999	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1650A>G; p.R550R; 12:2859394-2859394	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.719C>G; p.S240C; 12:2868690-2868690	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1607C>A; p.S536*; 12:2859437-2859437	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1747C>T; p.R583W; 12:2859297-2859297	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.741C>T; p.F247F; 12:2868668-2868668	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.681G>A; p.A227A; 12:2868728-2868728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1831G>A; p.A611T; 12:2859213-2859213	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.913G>C; p.V305L; 12:2866455-2866455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1795C>T; p.L599F; 12:2859249-2859249	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1137A>G; p.V379V; 12:2864449-2864449	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2122delC; p.E709fs*12; 12:2858922-2858922	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2122delC; p.E709fs*12; 12:2858922-2858922	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.742G>A; p.A248T; 12:2868667-2868667	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.742G>A; p.A248T; 12:2868667-2868667	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.392C>T; p.A131V; 12:2874087-2874087	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1849G>T; p.A617S; 12:2859195-2859195	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1735A>G; p.R579G; 12:2859309-2859309	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1266G>T; p.K422N; 12:2864320-2864320	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1077C>T; p.L359L; 12:2864696-2864696	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.562C>T; p.R188*; 12:2872188-2872188	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.562C>T; p.R188*; 12:2872188-2872188	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1822C>T; p.R608C; 12:2859222-2859222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1843T>A; p.F615I; 12:2859201-2859201	liver	carcinoma	Substitution - Missense
c.725T>A; p.M242K; 12:2868684-2868684	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.164C>G; p.S55C; 12:2874315-2874315	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1478C>T; p.P493L; 12:2859566-2859566	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2181T>C; p.F727F; 12:2858863-2858863	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1100T>C; p.M367T; 12:2864486-2864486	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.644G>T; p.R215L; 12:2872106-2872106	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.766C>G; p.R256G; 12:2868643-2868643	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1690T>A; p.C564S; 12:2859354-2859354	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1589C>T; p.P530L; 12:2859455-2859455	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1071C>T; p.T357T; 12:2864702-2864702	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.965A>T; p.Q322L; 12:2866403-2866403	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.864_865CC>A; p.N288fs*31; 12:2866503-2866504	lung	carcinoma; adenocarcinoma	Complex - frameshift
c.122C>G; p.S41C; 12:2874357-2874357	oesophagus	carcinoma	Substitution - Missense
c.2211C>T; p.V737V; 12:2858833-2858833	oesophagus	carcinoma	Substitution - coding silent
c.342C>T; p.A114A; 12:2874137-2874137	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1048C>T; p.R350C; 12:2864725-2864725	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.582A>C; p.G194G; 12:2872168-2872168	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2136A>G; p.Q712Q; 12:2858908-2858908	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1092G>C; p.R364R; 12:2864494-2864494	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1866T>C; p.P622P; 12:2859178-2859178	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2020G>C; p.D674H; 12:2859024-2859024	pancreas	carcinoma	Substitution - Missense
c.2020G>C; p.D674H; 12:2859024-2859024	pancreas	carcinoma	Substitution - Missense
c.2020G>C; p.D674H; 12:2859024-2859024	pancreas	carcinoma	Substitution - Missense
c.2020G>C; p.D674H; 12:2859024-2859024	pancreas	carcinoma	Substitution - Missense
c.1324C>T; p.R442*; 12:2861355-2861355	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.598A>G; p.I200V; 12:2872152-2872152	prostate	carcinoma	Substitution - Missense
c.356C>T; p.P119L; 12:2874123-2874123	skin	malignant_melanoma	Substitution - Missense
c.933C>T; p.H311H; 12:2866435-2866435	skin	malignant_melanoma	Substitution - coding silent
c.2171C>T; p.S724F; 12:2858873-2858873	skin	malignant_melanoma	Substitution - Missense
c.1410T>C; p.P470P; 12:2859634-2859634	skin	malignant_melanoma	Substitution - coding silent
c.1118G>A; p.R373Q; 12:2864468-2864468	skin	malignant_melanoma	Substitution - Missense
c.458C>T; p.P153L; 12:2874021-2874021	skin	malignant_melanoma	Substitution - Missense
c.363C>T; p.L121L; 12:2874116-2874116	skin	malignant_melanoma	Substitution - coding silent
c.253C>T; p.H85Y; 12:2874226-2874226	skin	malignant_melanoma	Substitution - Missense
c.457C>T; p.P153S; 12:2874022-2874022	skin	malignant_melanoma	Substitution - Missense
c.1218G>A; p.M406I; 12:2864368-2864368	skin	malignant_melanoma	Substitution - Missense
c.2138G>A; p.R713K; 12:2858906-2858906	skin	malignant_melanoma	Substitution - Missense
c.1736G>A; p.R579K; 12:2859308-2859308	skin	malignant_melanoma	Substitution - Missense
c.2111G>A; p.S704N; 12:2858933-2858933	skin	malignant_melanoma	Substitution - Missense
c.2275G>A; p.G759S; 12:2858769-2858769	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.45G>A; p.R15R; 12:2874434-2874434	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2090T>C; p.L697P; 12:2858954-2858954	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1181C>T; p.S394L; 12:2864405-2864405	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1096A>C; p.K366Q; 12:2864490-2864490	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.643C>T; p.R215*; 12:2872107-2872107	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.16C>T; p.R6C; 12:2874463-2874463	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1094G>A; p.R365Q; 12:2864492-2864492	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.366G>A; p.R122R; 12:2874113-2874113	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.429A>C; p.P143P; 12:2874050-2874050	thyroid	carcinoma	Substitution - coding silent
c.954G>C; p.L318F; 12:2866414-2866414	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1185G>A; p.V395V; 12:2864401-2864401	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2365G>A; p.D789N; 12:2858679-2858679	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1725G>A; p.E575E; 12:2859319-2859319	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1253G>A; p.R418H; 12:2864333-2864333	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1253G>A; p.R418H; 12:2864333-2864333	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1570G>C; p.E524Q; 12:2859474-2859474	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1570G>C; p.E524Q; 12:2859474-2859474	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1620G>C; p.W540C; 12:2859424-2859424	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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