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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2274

Name

FHL2

Synonymous

four and a half LIM domains 2;FHL2;four and a half LIM domains 2

Definition

LIM domain protein DRAL|aging-associated gene 11|down-regulated in rhabdomyosarcoma LIM protein|four and a half LIM domains protein 2|skeletal muscle LIM-protein 3

Position

2q12.2

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.725G>A; p.R242Q; 2:105361398-105361398

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.584T>A; p.L195Q; 2:105363389-105363389

 breastcarcinomaSubstitution - Missense

c.174C>G; p.D58E; 2:105373716-105373716

 breastcarcinomaSubstitution - Missense

c.285C>A; p.N95K; 2:105373605-105373605

 breastcarcinomaSubstitution - Missense

c.270A>G; p.T90T; 2:105373620-105373620

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.34G>A; p.E12K; 2:105386483-105386483

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.595C>T; p.R199C; 2:105363378-105363378

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.173A>T; p.D58V; 2:105373717-105373717

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelodysplastic_syndromeSubstitution - Missense

c.141C>T; p.I47I; 2:105386376-105386376

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.700A>G; p.T234A; 2:105361423-105361423

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.10C>T; p.R4C; 2:105386507-105386507

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.575G>A; p.R192K; 2:105363398-105363398

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.725G>A; p.R242Q; 2:105361398-105361398

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.804C>T; p.D268D; 2:105361319-105361319

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.819C>T; p.P273P; 2:105361304-105361304

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.782G>A; p.R261H; 2:105361341-105361341

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.801G>A; p.R267R; 2:105361322-105361322

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.613G>T; p.D205Y; 2:105363360-105363360

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.328C>G; p.P110A; 2:105373562-105373562

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.158A>T; p.D53V; 2:105373732-105373732

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.284A>G; p.N95S; 2:105373606-105373606

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.207G>C; p.S69S; 2:105373683-105373683

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.656A>C; p.K219T; 2:105363317-105363317

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.223C>T; p.L75L; 2:105373667-105373667

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.808A>T; p.I270F; 2:105361315-105361315

 pancreascarcinomaSubstitution - Missense

c.564C>A; p.C188*; 2:105363409-105363409

 pancreascarcinomaSubstitution - Nonsense

c.291C>A; p.Y97*; 2:105373599-105373599

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.822C>T; p.D274D; 2:105361301-105361301

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.426C>T; p.I142I; 2:105367645-105367645

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.61C>T; p.L21L; 2:105386456-105386456

 skinmalignant_melanomaSubstitution - coding silent

c.607C>T; p.R203C; 2:105363366-105363366

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.74G>T; p.S25I; 2:105386443-105386443

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.839G>T; p.*280L; 2:105361284-105361284

 stomachcarcinoma; diffuse_adenocarcinomaNonstop extension

c.391C>A; p.R131S; 2:105367680-105367680

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.713C>T; p.S238F; 2:105361410-105361410

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.224T>C; p.L75P; 2:105373666-105373666

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.724C>T; p.R242W; 2:105361399-105361399

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.609C>T; p.R203R; 2:105363364-105363364

 urinary_tract; bladdercarcinomaSubstitution - coding silent