Entrez Gene

Basic Information
Gene ID	2255
Name	FGF10
Synonymous	fibroblast growth factor 10;FGF10;fibroblast growth factor 10
Definition	FGF-10\|keratinocyte growth factor 2\|produced by fibroblasts of urinary bladder lamina propria
Position	5p13-p12
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.64T>C; p.C22R; 5:44388619-44388619	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.578G>A; p.R193Q; 5:44305044-44305044	breast	carcinoma	Substitution - Missense
c.257C>T; p.T86I; 5:44388426-44388426	breast	carcinoma	Substitution - Missense
c.616G>T; p.V206L; 5:44305006-44305006	central_nervous_system; brain	glioma; astrocytoma_Grade_III	Substitution - Missense
c.452A>C; p.K151T; 5:44305170-44305170	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.73T>C; p.L25L; 5:44388610-44388610	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.92C>T; p.S31F; 5:44388591-44388591	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.285C>T; p.N95N; 5:44388398-44388398	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.429+9T>C; p.?; 5:44310418-44310418	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Unknown
c.97G>A; p.V33I; 5:44388586-44388586	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.97G>A; p.V33I; 5:44388586-44388586	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.118C>A; p.L40I; 5:44388565-44388565	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.433G>T; p.E145*; 5:44305189-44305189	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.68_70delGCT; p.C23delC; 5:44388613-44388615	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.97G>A; p.V33I; 5:44388586-44388586	large_intestine; caecum	adenoma	Substitution - Missense
c.238A>C; p.R80R; 5:44388445-44388445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.383G>A; p.S128N; 5:44310473-44310473	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.383G>A; p.S128N; 5:44310473-44310473	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.544G>T; p.G182*; 5:44305078-44305078	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.386A>G; p.N129S; 5:44310470-44310470	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.203G>A; p.R68Q; 5:44388480-44388480	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.158C>A; p.S53Y; 5:44388525-44388525	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.610A>G; p.M204V; 5:44305012-44305012	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.161C>T; p.S54F; 5:44388522-44388522	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.268C>A; p.L90I; 5:44388415-44388415	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.209A>G; p.Y70C; 5:44388474-44388474	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.239G>T; p.R80I; 5:44388444-44388444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.354C>T; p.I118I; 5:44310502-44310502	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.557C>A; p.P186Q; 5:44305065-44305065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.584A>T; p.K195I; 5:44305038-44305038	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5G>C; p.W2S; 5:44388678-44388678	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.578G>T; p.R193L; 5:44305044-44305044	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.477T>A; p.N159K; 5:44305145-44305145	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.214C>T; p.H72Y; 5:44388469-44388469	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.418C>A; p.L140I; 5:44310438-44310438	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.238A>G; p.R80G; 5:44388445-44388445	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.279G>C; p.E93D; 5:44388404-44388404	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.471G>T; p.E157D; 5:44305151-44305151	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.471G>T; p.E157D; 5:44305151-44305151	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.111C>T; p.C37C; 5:44388572-44388572	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.165C>T; p.S55S; 5:44388518-44388518	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.32C>T; p.S11L; 5:44388651-44388651	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.358G>C; p.V120L; 5:44310498-44310498	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.162C>A; p.S54S; 5:44388521-44388521	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.483C>A; p.Y161*; 5:44305139-44305139	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.354C>T; p.I118I; 5:44310502-44310502	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.452A>C; p.K151T; 5:44305170-44305170	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.445G>T; p.D149Y; 5:44305177-44305177	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.550G>T; p.G184*; 5:44305072-44305072	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.318C>T; p.C106C; 5:44388365-44388365	oesophagus	carcinoma	Substitution - coding silent
c.446A>T; p.D149V; 5:44305176-44305176	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.544G>A; p.G182R; 5:44305078-44305078	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.334G>T; p.E112*; 5:44310522-44310522	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Nonsense
c.298G>A; p.G100R; 5:44388385-44388385	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>A; p.V123I; 5:44310489-44310489	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.486T>C; p.N162N; 5:44305136-44305136	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.561G>A; p.R187R; 5:44305061-44305061	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.178C>G; p.P60A; 5:44388505-44388505	ovary	other; neoplasm	Substitution - Missense
c.50C>A; p.P17H; 5:44388633-44388633	pancreas	carcinoma	Substitution - Missense
c.286G>T; p.G96W; 5:44388397-44388397	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.68_70delGCT; p.C23delC; 5:44388613-44388615	skin	malignant_melanoma	Deletion - In frame
c.68_70delGCT; p.C23delC; 5:44388613-44388615	skin	malignant_melanoma	Deletion - In frame
c.578G>A; p.R193Q; 5:44305044-44305044	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.515A>T; p.N172I; 5:44305107-44305107	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.164C>T; p.S55F; 5:44388519-44388519	skin	malignant_melanoma	Substitution - Missense
c.561G>A; p.R187R; 5:44305061-44305061	skin	malignant_melanoma	Substitution - coding silent
c.561G>A; p.R187R; 5:44305061-44305061	skin	malignant_melanoma	Substitution - coding silent
c.424G>A; p.G142S; 5:44310432-44310432	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.472G>A; p.E158K; 5:44305150-44305150	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.286G>A; p.G96R; 5:44388397-44388397	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.497C>T; p.S166L; 5:44305125-44305125	skin	malignant_melanoma	Substitution - Missense
c.582G>A; p.R194R; 5:44305040-44305040	skin	malignant_melanoma	Substitution - coding silent
c.582G>A; p.R194R; 5:44305040-44305040	skin	malignant_melanoma	Substitution - coding silent
c.354C>T; p.I118I; 5:44310502-44310502	skin; trunk	malignant_melanoma; nodular	Substitution - coding silent
c.608C>T; p.P203L; 5:44305014-44305014	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.146C>T; p.A49V; 5:44388537-44388537	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.394T>G; p.L132V; 5:44310462-44310462	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.596C>T; p.A199V; 5:44305026-44305026	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.312G>A; p.E104E; 5:44388371-44388371	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.321G>A; p.P107P; 5:44388362-44388362	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.235T>G; p.W79G; 5:44388448-44388448	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.14T>G; p.I5R; 5:44388669-44388669	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.295A>G; p.S99G; 5:44388388-44388388	thyroid	other; neoplasm	Substitution - Missense
c.292G>A; p.V98I; 5:44388391-44388391	thyroid	other; neoplasm	Substitution - Missense
c.155C>G; p.S52C; 5:44388528-44388528	urinary_tract; bladder	carcinoma	Substitution - Missense

Oncogene database

COSMIC confirmed somatic mutation [Top]

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