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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2251

Name

FGF6

Synonymous

fibroblast growth factor 6;FGF6;fibroblast growth factor 6

Definition

FGF-6|HST-2|HSTF-2|heparin secretory-transforming protein 2|heparin-binding growth factor 6

Position

12p13

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.565G>C; p.V189L; 12:4434277-4434277

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.211G>A; p.G71R; 12:4445360-4445360

 bone; fibulaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.562C>T; p.R188W; 12:4434280-4434280

 breastcarcinomaSubstitution - Missense

c.367G>A; p.V123M; 12:4444216-4444216

 breastcarcinomaSubstitution - Missense

c.128G>A; p.R43H; 12:4445443-4445443

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.321C>T; p.S107S; 12:4445250-4445250

 breastcarcinomaSubstitution - coding silent

c.184C>T; p.R62C; 12:4445387-4445387

 breastcarcinomaSubstitution - Missense

c.306C>G; p.P102P; 12:4445265-4445265

 breastcarcinomaSubstitution - coding silent

c.377G>A; p.G126D; 12:4444206-4444206

 central_nervous_system; braingliomaSubstitution - Missense

c.559G>A; p.G187R; 12:4434283-4434283

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.379G>A; p.V127M; 12:4444204-4444204

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.481G>T; p.E161*; 12:4434361-4434361

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.450G>A; p.T150T; 12:4444133-4444133

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.450+1G>A; p.?; 12:4444132-4444132

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.367G>A; p.V123M; 12:4444216-4444216

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; myelofibrosisSubstitution - Missense

c.107T>C; p.V36A; 12:4445464-4445464

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.328C>A; p.H110N; 12:4445243-4445243

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.192G>A; p.G64G; 12:4445379-4445379

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.238G>T; p.V80L; 12:4445333-4445333

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.351G>C; p.L117L; 12:4444232-4444232

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.237G>C; p.L79F; 12:4445334-4445334

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.562C>T; p.R188W; 12:4434280-4434280

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.307G>A; p.D103N; 12:4445264-4445264

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.63G>A; p.T21T; 12:4445508-4445508

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.508G>A; p.A170T; 12:4434334-4434334

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.49C>T; p.R17C; 12:4445522-4445522

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.187G>A; p.A63T; 12:4445384-4445384

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.128G>A; p.R43H; 12:4445443-4445443

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.38G>A; p.R13Q; 12:4445533-4445533

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125*; 12:4444210-4444210

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.366T>C; p.T122T; 12:4444217-4444217

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.188C>T; p.A63V; 12:4445383-4445383

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.186C>T; p.R62R; 12:4445385-4445385

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.186C>T; p.R62R; 12:4445385-4445385

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.185G>A; p.R62H; 12:4445386-4445386

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.607C>A; p.H203N; 12:4434235-4434235

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.37C>T; p.R13W; 12:4445534-4445534

 large_intestine; colonadenomaSubstitution - Missense

c.414C>T; p.F138F; 12:4444169-4444169

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.414C>T; p.F138F; 12:4444169-4444169

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.563G>A; p.R188Q; 12:4434279-4434279

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.228T>C; p.S76S; 12:4445343-4445343

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.594C>G; p.I198M; 12:4434248-4434248

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.452C>A; p.P151H; 12:4434390-4434390

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.127C>A; p.R43S; 12:4445444-4445444

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.223delG; p.E75fs*54; 12:4445348-4445348

 lungcarcinoma; adenocarcinomaDeletion - Frameshift

c.176_177CC>AA; p.S59*; 12:4445394-4445395

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.161G>T; p.W54L; 12:4445410-4445410

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.190G>T; p.G64W; 12:4445381-4445381

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.342C>T; p.P114P; 12:4445229-4445229

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.58G>T; p.G20C; 12:4445513-4445513

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.11G>T; p.G4V; 12:4445560-4445560

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.530A>T; p.Q177L; 12:4434312-4434312

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.374G>A; p.R125Q; 12:4444209-4444209

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.307G>T; p.D103Y; 12:4445264-4445264

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.32T>C; p.M11T; 12:4445539-4445539

 NSNSSubstitution - Missense

c.389T>A; p.L130H; 12:4444194-4444194

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.571C>T; p.R191W; 12:4434271-4434271

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.572G>A; p.R191Q; 12:4434270-4434270

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.227G>T; p.S76I; 12:4445344-4445344

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.367G>A; p.V123M; 12:4444216-4444216

 pancreascarcinomaSubstitution - Missense

c.395G>C; p.G132A; 12:4444188-4444188

 pancreascarcinomaSubstitution - Missense

c.561A>G; p.G187G; 12:4434281-4434281

 pancreascarcinomaSubstitution - coding silent

c.242G>C; p.G81A; 12:4445329-4445329

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.415G>A; p.V139I; 12:4444168-4444168

 prostatecarcinomaSubstitution - Missense

c.250C>T; p.R84W; 12:4445321-4445321

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.612C>T; p.F204F; 12:4434230-4434230

 skinmalignant_melanomaSubstitution - coding silent

c.2T>G; p.M1R; 12:4445569-4445569

 skinmalignant_melanomaSubstitution - Missense

c.434G>A; p.G145E; 12:4444149-4444149

 skinmalignant_melanomaSubstitution - Missense

c.434G>A; p.G145E; 12:4444149-4444149

 skinmalignant_melanomaSubstitution - Missense

c.460C>T; p.Q154*; 12:4434382-4434382

 skinmalignant_melanomaSubstitution - Nonsense

c.506A>T; p.N169I; 12:4434336-4434336

 skinmalignant_melanomaSubstitution - Missense

c.223G>A; p.E75K; 12:4445348-4445348

 skinmalignant_melanomaSubstitution - Missense

c.355G>A; p.E119K; 12:4444228-4444228

 skin; trunkmalignant_melanoma; nodularSubstitution - Missense

c.258G>A; p.R86R; 12:4445313-4445313

 skinmalignant_melanomaSubstitution - coding silent

c.437G>A; p.R146K; 12:4444146-4444146

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.204G>A; p.E68E; 12:4445367-4445367

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.27C>T; p.I9I; 12:4445544-4445544

 skinmalignant_melanomaSubstitution - coding silent

c.414C>T; p.F138F; 12:4444169-4444169

 skinmalignant_melanomaSubstitution - coding silent

c.414C>T; p.F138F; 12:4444169-4444169

 skinmalignant_melanomaSubstitution - coding silent

c.415G>A; p.V139I; 12:4444168-4444168

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.321C>T; p.S107S; 12:4445250-4445250

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.449C>T; p.T150M; 12:4444134-4444134

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.256C>T; p.R86W; 12:4445315-4445315

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.250C>T; p.R84W; 12:4445321-4445321

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.104T>C; p.V35A; 12:4445467-4445467

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.572G>A; p.R191Q; 12:4434270-4434270

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.141G>A; p.T47T; 12:4445430-4445430

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.521A>T; p.D174V; 12:4434321-4434321

 thyroidother; neoplasmSubstitution - Missense

c.189C>G; p.A63A; 12:4445382-4445382

 thyroidother; neoplasmSubstitution - coding silent

c.128G>A; p.R43H; 12:4445443-4445443

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.477C>T; p.F159F; 12:4434365-4434365

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.373C>T; p.R125*; 12:4444210-4444210

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.373C>T; p.R125*; 12:4444210-4444210

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Nonsense

c.374G>A; p.R125Q; 12:4444209-4444209

 urinary_tract; bladdercarcinomaSubstitution - Missense