ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2017

Name

CTTN

Synonymous

cortactin;CTTN;cortactin

Definition

1110020L01Rik|amplaxin|ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)|oncogene EMS1|src substrate cortactin

Position

11q13

Gene Type

protein-coding

COSMIC confirmed somatic mutation   [Top]

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1480G>C; p.G494R; 11:70433682-70433682

 breastcarcinoma; lobular_carcinomaSubstitution - Missense

c.1484T>G; p.I495S; 11:70433686-70433686

 breastcarcinomaSubstitution - Missense

c.254G>C; p.G85A; 11:70409923-70409923

 breastcarcinomaSubstitution - Missense

c.1234G>A; p.E412K; 11:70431248-70431248

 breastcarcinomaSubstitution - Missense

c.712G>A; p.V238M; 11:70420432-70420432

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.437A>G; p.E146G; 11:70415697-70415697

 central_nervous_system; braingliomaSubstitution - Missense

c.1326G>A; p.P442P; 11:70433160-70433160

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.211G>A; p.E71K; 11:70409880-70409880

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1459G>A; p.D487N; 11:70433661-70433661

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1491C>T; p.A497A; 11:70433693-70433693

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1547A>T; p.D516V; 11:70435056-70435056

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1521C>T; p.G507G; 11:70435030-70435030

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1271C>T; p.A424V; 11:70433105-70433105

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.318G>A; p.S106S; 11:70414568-70414568

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.627C>T; p.S209S; 11:70419804-70419804

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1055C>T; p.A352V; 11:70429078-70429078

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.918C>T; p.F306F; 11:70422956-70422956

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.502C>T; p.R168*; 11:70417057-70417057

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.1318A>C; p.T440P; 11:70433152-70433152

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.989T>A; p.V330E; 11:70425363-70425363

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.948G>A; p.R316R; 11:70422986-70422986

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.1309G>C; p.V437L; 11:70433143-70433143

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1072G>A; p.A358T; 11:70429095-70429095

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.72C>T; p.T24T; 11:70407369-70407369

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1494C>T; p.V498V; 11:70433696-70433696

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.546G>A; p.T182T; 11:70417101-70417101

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1473C>T; p.N491N; 11:70433675-70433675

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.48C>T; p.D16D; 11:70407345-70407345

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.48C>T; p.D16D; 11:70407345-70407345

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1377G>A; p.Q459Q; 11:70433211-70433211

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.932G>A; p.G311E; 11:70422970-70422970

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.359G>T; p.G120V; 11:70414609-70414609

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.750G>T; p.W250C; 11:70420470-70420470

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1203G>A; p.T401T; 11:70431217-70431217

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1203G>A; p.T401T; 11:70431217-70431217

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1271C>T; p.A424V; 11:70433105-70433105

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1518G>A; p.A506A; 11:70435027-70435027

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1593C>T; p.R531R; 11:70435102-70435102

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1581C>T; p.D527D; 11:70435090-70435090

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1466A>G; p.Y489C; 11:70433668-70433668

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.585C>T; p.F195F; 11:70419762-70419762

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.931G>A; p.G311R; 11:70422969-70422969

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.819C>T; p.F273F; 11:70421498-70421498

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1202C>T; p.T401M; 11:70431216-70431216

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.397G>T; p.D133Y; 11:70414647-70414647

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.1325C>T; p.P442L; 11:70433159-70433159

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.A17T; 11:70407346-70407346

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.712G>T; p.V238L; 11:70420432-70420432

 livercarcinomaSubstitution - Missense

c.712G>T; p.V238L; 11:70420432-70420432

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.499G>A; p.D167N; 11:70417054-70417054

 livercarcinomaSubstitution - Missense

c.518C>T; p.A173V; 11:70417073-70417073

 livercarcinomaSubstitution - Missense

c.399T>A; p.D133E; 11:70414649-70414649

 livercarcinomaSubstitution - Missense

c.399T>A; p.D133E; 11:70414649-70414649

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.400C>A; p.Q134K; 11:70414650-70414650

 livercarcinomaSubstitution - Missense

c.400C>A; p.Q134K; 11:70414650-70414650

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1320G>A; p.T440T; 11:70433154-70433154

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.701G>A; p.G234E; 11:70420421-70420421

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1232C>T; p.T411I; 11:70431246-70431246

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.88-1G>C; p.?; 11:70407517-70407517

 lung; right_upper_lobecarcinoma; adenocarcinomaUnknown

c.999C>G; p.A333A; 11:70425373-70425373

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1491C>T; p.A497A; 11:70433693-70433693

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1597G>T; p.V533L; 11:70435106-70435106

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.1474G>C; p.D492H; 11:70433676-70433676

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1582G>C; p.G528R; 11:70435091-70435091

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1250C>A; p.S417*; 11:70431264-70431264

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1474G>T; p.D492Y; 11:70433676-70433676

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.210G>T; p.K70N; 11:70409879-70409879

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1359C>T; p.Y453Y; 11:70433193-70433193

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.311A>G; p.Y104C; 11:70414561-70414561

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.163A>T; p.I55L; 11:70409832-70409832

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.791-1G>A; p.?; 11:70421469-70421469

 lungcarcinoma; adenocarcinomaUnknown

c.1387G>C; p.A463P; 11:70433221-70433221

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.53G>T; p.G18V; 11:70407350-70407350

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.754C>T; p.H252Y; 11:70420474-70420474

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.809G>A; p.G270E; 11:70421488-70421488

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1616G>T; p.G539V; 11:70435125-70435125

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.513G>T; p.K171N; 11:70417068-70417068

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.646C>T; p.Q216*; 11:70419823-70419823

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1126C>T; p.R376W; 11:70429149-70429149

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.932G>C; p.G311A; 11:70422970-70422970

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1083A>G; p.K361K; 11:70429106-70429106

 pancreascarcinomaSubstitution - coding silent

c.1077G>A; p.K359K; 11:70429100-70429100

 pancreascarcinomaSubstitution - coding silent

c.967A>G; p.T323A; 11:70425341-70425341

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.831G>A; p.S277S; 11:70421510-70421510

 pancreascarcinomaSubstitution - coding silent

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinomaSubstitution - Missense

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinomaSubstitution - Missense

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinomaSubstitution - Missense

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinomaSubstitution - Missense

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.1202C>T; p.T401M; 11:70431216-70431216

 pancreascarcinomaSubstitution - Missense

c.821G>T; p.G274V; 11:70421500-70421500

 pancreascarcinomaSubstitution - Missense

c.517G>T; p.A173S; 11:70417072-70417072

 peritoneum; appendixother; pseudomyxoma_peritoneiSubstitution - Missense

c.1139A>G; p.E380G; 11:70429162-70429162

 pleurapulmonary_blastomaSubstitution - Missense

c.637T>G; p.F213V; 11:70419814-70419814

 prostatecarcinomaSubstitution - Missense

c.1387G>A; p.A463T; 11:70433221-70433221

 prostatecarcinomaSubstitution - Missense

c.1313G>A; p.S438N; 11:70433147-70433147

 prostatecarcinomaSubstitution - Missense

c.603C>T; p.I201I; 11:70419780-70419780

 skinmalignant_melanomaSubstitution - coding silent

c.814A>G; p.K272E; 11:70421493-70421493

 skinmalignant_melanomaSubstitution - Missense

c.932G>A; p.G311E; 11:70422970-70422970

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.629_630CC>TT; p.A210V; 11:70419806-70419807

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.338C>T; p.S113L; 11:70414588-70414588

 skinmalignant_melanomaSubstitution - Missense

c.1425_1426CC>TT; p.P476S; 11:70433259-70433260

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.165A>T; p.I55I; 11:70409834-70409834

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.242C>T; p.S81F; 11:70409911-70409911

 skinmalignant_melanomaSubstitution - Missense

c.590G>A; p.G197D; 11:70419767-70419767

 skinmalignant_melanomaSubstitution - Missense

c.286G>A; p.D96N; 11:70409955-70409955

 skin; head_neckmalignant_melanoma; superficial_spreadingSubstitution - Missense

c.575C>T; p.S192F; 11:70419752-70419752

 skinmalignant_melanomaSubstitution - Missense

c.1427C>T; p.P476L; 11:70433261-70433261

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.782C>T; p.S261F; 11:70420502-70420502

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1116G>A; p.E372E; 11:70429139-70429139

 skinmalignant_melanomaSubstitution - coding silent

c.1039A>G; p.T347A; 11:70429062-70429062

 skinmalignant_melanomaSubstitution - Missense

c.354C>T; p.V118V; 11:70414604-70414604

 skinmalignant_melanomaSubstitution - coding silent

c.1493T>C; p.V498A; 11:70433695-70433695

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.427G>A; p.G143R; 11:70415687-70415687

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1219G>A; p.A407T; 11:70431233-70431233

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.982A>G; p.T328A; 11:70425356-70425356

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.656C>T; p.T219M; 11:70419833-70419833

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.769C>T; p.Q257*; 11:70420489-70420489

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.630C>A; p.A210A; 11:70419807-70419807

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.120T>C; p.G40G; 11:70407550-70407550

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.766T>A; p.L256M; 11:70420486-70420486

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.705A>G; p.K235K; 11:70420425-70420425

 thyroidother; neoplasmSubstitution - coding silent

c.485A>G; p.Y162C; 11:70417040-70417040

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.958-1G>A; p.?; 11:70425331-70425331

 urinary_tract; bladdercarcinomaUnknown

c.958-1G>A; p.?; 11:70425331-70425331

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaUnknown

c.1447G>A; p.D483N; 11:70433649-70433649

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.1447G>A; p.D483N; 11:70433649-70433649

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1212G>C; p.V404V; 11:70431226-70431226

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1528G>A; p.E510K; 11:70435037-70435037

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.646C>G; p.Q216E; 11:70419823-70419823

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.88-8C>G; p.?; 11:70407510-70407510

 urinary_tract; bladdercarcinomaUnknown

c.698G>A; p.G233E; 11:70420418-70420418

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1614C>T; p.Y538Y; 11:70435123-70435123

 urinary_tract; bladdercarcinomaSubstitution - coding silent