Entrez Gene

Basic Information
Gene ID	1969
Name	EPHA2
Synonymous	EPH receptor A2;EPHA2;EPH receptor A2
Definition	ephrin type-A receptor 2\|epithelial cell receptor protein tyrosine kinase\|soluble EPHA2 variant 1\|tyrosine-protein kinase receptor ECK
Position	1p36
Gene Type	protein-coding

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
COSMIC confirmed somatic mutation [Top]

c.2563C>A; p.Q855K; 1:16130332-16130332	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.981delA; p.S330fs*63; 1:16138184-16138184	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Deletion - Frameshift
c.307C>T; p.R103C; 1:16148894-16148894	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.1243delC; p.R415fs*8; 1:16137922-16137922	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Deletion - Frameshift
c.738C>T; p.H246H; 1:16148463-16148463	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.979+1G>A; p.?; 1:16138274-16138274	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Unknown
c.480C>T; p.H160H; 1:16148721-16148721	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2536A>G; p.I846V; 1:16130359-16130359	bone; rib	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.493G>A; p.V165M; 1:16148708-16148708	breast	carcinoma	Substitution - Missense
c.2601C>T; p.I867I; 1:16130294-16130294	breast	carcinoma	Substitution - coding silent
c.2601C>T; p.I867I; 1:16130294-16130294	breast	carcinoma	Substitution - coding silent
c.1207G>A; p.E403K; 1:16137958-16137958	breast	carcinoma	Substitution - Missense
c.2301C>T; p.D767D; 1:16132088-16132088	breast	carcinoma	Substitution - coding silent
c.2473G>T; p.E825*; 1:16131723-16131723	breast	carcinoma	Substitution - Nonsense
c.625G>A; p.A209T; 1:16148576-16148576	breast	carcinoma	Substitution - Missense
c.1012G>A; p.V338M; 1:16138153-16138153	breast	carcinoma	Substitution - Missense
c.2227C>G; p.R743G; 1:16132162-16132162	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2450C>T; p.P817L; 1:16131746-16131746	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.146G>A; p.G49D; 1:16150903-16150903	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; large_cell	Substitution - Missense
c.724G>A; p.E242K; 1:16148477-16148477	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.653C>G; p.S218C; 1:16148548-16148548	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1200C>T; p.S400S; 1:16137965-16137965	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1911G>T; p.G637G; 1:16133322-16133322	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2040C>T; p.G680G; 1:16133193-16133193	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1130G>T; p.G377V; 1:16138035-16138035	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.334G>A; p.A112T; 1:16148867-16148867	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.979+1G>A; p.?; 1:16138274-16138274	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1703G>A; p.R568H; 1:16133895-16133895	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1678C>T; p.R560C; 1:16134472-16134472	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.830C>T; p.S277L; 1:16138424-16138424	eye; uveal_tract	malignant_melanoma; spindle	Substitution - Missense
c.2825+5G>T; p.?; 1:16129429-16129429	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Unknown
c.1359C>T; p.S453S; 1:16135724-16135724	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2723C>T; p.T908M; 1:16129536-16129536	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; essential_thrombocythaemia	Substitution - Missense
c.769A>C; p.I257L; 1:16148432-16148432	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.2298C>T; p.D766D; 1:16132091-16132091	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.952C>T; p.Q318*; 1:16138302-16138302	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2222C>T; p.A741V; 1:16132167-16132167	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.732T>C; p.R244R; 1:16148469-16148469	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.823G>T; p.A275S; 1:16148378-16148378	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1940C>T; p.T647M; 1:16133293-16133293	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1383G>A; p.P461P; 1:16135700-16135700	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.762G>A; p.L254L; 1:16148439-16148439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1233C>A; p.T411T; 1:16137932-16137932	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2040C>T; p.G680G; 1:16133193-16133193	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2161C>T; p.R721W; 1:16132228-16132228	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1630G>A; p.G544S; 1:16134520-16134520	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1379delC; p.P460fs*33; 1:16135704-16135704	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1379delC; p.P460fs*33; 1:16135704-16135704	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1379delC; p.P460fs*33; 1:16135704-16135704	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1379delC; p.P460fs*33; 1:16135704-16135704	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1379delC; p.P460fs*33; 1:16135704-16135704	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1617C>T; p.G539G; 1:16134533-16134533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.141G>A; p.P47P; 1:16150908-16150908	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1195G>A; p.V399M; 1:16137970-16137970	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.810G>T; p.E270D; 1:16148391-16148391	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1988A>G; p.E663G; 1:16133245-16133245	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>T; p.Y87Y; 1:16148940-16148940	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2329G>T; p.G777C; 1:16131867-16131867	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1228T>A; p.F410I; 1:16137937-16137937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2246G>A; p.S749N; 1:16132143-16132143	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.188C>T; p.P63L; 1:16149013-16149013	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2612T>G; p.L871R; 1:16130283-16130283	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1147G>A; p.V383M; 1:16138018-16138018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1382C>T; p.P461L; 1:16135701-16135701	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1453C>T; p.R485C; 1:16135165-16135165	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.987C>T; p.P329P; 1:16138178-16138178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.987C>T; p.P329P; 1:16138178-16138178	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.987C>T; p.P329P; 1:16138178-16138178	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.987C>T; p.P329P; 1:16138178-16138178	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1495C>A; p.P499T; 1:16135123-16135123	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2731G>A; p.E911K; 1:16129528-16129528	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2783C>A; p.A928D; 1:16129476-16129476	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2357C>T; p.P786L; 1:16131839-16131839	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2143C>T; p.Q715*; 1:16132246-16132246	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2143C>T; p.Q715*; 1:16132246-16132246	large_intestine; colon	carcinoma	Substitution - Nonsense
c.2143C>T; p.Q715*; 1:16132246-16132246	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1473C>T; p.S491S; 1:16135145-16135145	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2447G>A; p.R816Q; 1:16131749-16131749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2107T>C; p.F703L; 1:16132386-16132386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2127C>T; p.G709G; 1:16132262-16132262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1373delT; p.I458fs*35; 1:16135710-16135710	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.921C>T; p.C307C; 1:16138333-16138333	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.260A>G; p.Y87C; 1:16148941-16148941	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.260A>G; p.Y87C; 1:16148941-16148941	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.719delG; p.G240fs*153; 1:16148482-16148482	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.719delG; p.G240fs*153; 1:16148482-16148482	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1549delG; p.A517fs*21; 1:16135069-16135069	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2125G>A; p.G709S; 1:16132264-16132264	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.86-2A>G; p.?; 1:16150965-16150965	liver	carcinoma	Unknown
c.86-2A>G; p.?; 1:16150965-16150965	liver	carcinoma	Unknown
c.86-2A>G; p.?; 1:16150965-16150965	liver	carcinoma	Unknown
c.1429-2A>G; p.?; 1:16135191-16135191	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1672A>T; p.I558F; 1:16134478-16134478	liver	carcinoma	Substitution - Missense
c.2095G>A; p.A699T; 1:16132398-16132398	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2547C>A; p.L849L; 1:16130348-16130348	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.883G>A; p.E295K; 1:16138371-16138371	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1329G>T; p.R443S; 1:16135754-16135754	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2030G>T; p.R677L; 1:16133203-16133203	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1987G>T; p.E663*; 1:16133246-16133246	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.618_619GG>TT; p.Q206_G207>HC; 1:16148582-16148583	lung	carcinoma; adenocarcinoma	Complex - compound substitution
c.2520G>A; p.M840I; 1:16130375-16130375	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1618G>A; p.G540S; 1:16134532-16134532	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.440C>T; p.P147L; 1:16148761-16148761	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2528C>T; p.P843L; 1:16130367-16130367	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.836G>C; p.G279A; 1:16138418-16138418	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2447G>T; p.R816L; 1:16131749-16131749	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.424A>G; p.I142V; 1:16148777-16148777	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2785G>T; p.G929C; 1:16129474-16129474	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1274G>T; p.R425L; 1:16137891-16137891	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2614G>T; p.D872Y; 1:16130281-16130281	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1752C>T; p.P584P; 1:16133593-16133593	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1820A>C; p.E607A; 1:16133525-16133525	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.906G>A; p.E302E; 1:16138348-16138348	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.832C>T; p.P278S; 1:16138422-16138422	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2525G>A; p.C842Y; 1:16130370-16130370	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2287G>A; p.V763M; 1:16132102-16132102	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2217C>T; p.D739D; 1:16132172-16132172	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.836G>A; p.G279E; 1:16138418-16138418	NS	malignant_melanoma	Substitution - Missense
c.836G>A; p.G279E; 1:16138418-16138418	NS	malignant_melanoma	Substitution - Missense
c.398A>G; p.N133S; 1:16148803-16148803	NS	malignant_melanoma	Substitution - Missense
c.1151G>A; p.R384H; 1:16138014-16138014	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.703G>T; p.V235L; 1:16148498-16148498	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.166C>T; p.Q56*; 1:16149035-16149035	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1379delC; p.P460fs*33; 1:16135704-16135704	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.635delC; p.P212fs*181; 1:16148566-16148566	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.409C>T; p.R137C; 1:16148792-16148792	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.440C>T; p.P147L; 1:16148761-16148761	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2740G>T; p.E914*; 1:16129519-16129519	oesophagus	carcinoma	Substitution - Nonsense
c.155G>A; p.W52*; 1:16149046-16149046	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2736G>C; p.W912C; 1:16129523-16129523	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.602G>T; p.C201F; 1:16148599-16148599	ovary	other; neoplasm	Substitution - Missense
c.602G>T; p.C201F; 1:16148599-16148599	ovary	other; neoplasm	Substitution - Missense
c.152G>C; p.G51A; 1:16150897-16150897	ovary	other; neoplasm	Substitution - Missense
c.980G>T; p.R327L; 1:16138185-16138185	ovary	other; neoplasm	Substitution - Missense
c.2869C>T; p.R957C; 1:16125277-16125277	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2062A>C; p.M688L; 1:16132431-16132431	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.717G>A; p.G239G; 1:16148484-16148484	pancreas	carcinoma	Substitution - coding silent
c.1987G>A; p.E663K; 1:16133246-16133246	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.922G>A; p.E308K; 1:16138332-16138332	pancreas	carcinoma	Substitution - Missense
c.507C>T; p.S169S; 1:16148694-16148694	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent
c.2021A>G; p.N674S; 1:16133212-16133212	pancreas	carcinoma	Substitution - Missense
c.2581C>T; p.R861C; 1:16130314-16130314	pancreas	carcinoma	Substitution - Missense
c.2581C>T; p.R861C; 1:16130314-16130314	pancreas	carcinoma	Substitution - Missense
c.570G>A; p.A190A; 1:16148631-16148631	prostate	adenoma	Substitution - coding silent
c.2285G>A; p.R762H; 1:16132104-16132104	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1532C>T; p.T511M; 1:16135086-16135086	prostate	carcinoma	Substitution - Missense
c.1343G>A; p.S448N; 1:16135740-16135740	prostate	carcinoma	Substitution - Missense
c.2629G>T; p.A877S; 1:16130266-16130266	prostate	adenoma	Substitution - Missense
c.2711T>G; p.V904G; 1:16129548-16129548	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2914G>C; p.V972L; 1:16125232-16125232	prostate	carcinoma	Substitution - Missense
c.635C>T; p.P212L; 1:16148566-16148566	skin	malignant_melanoma	Substitution - Missense
c.1010C>T; p.A337V; 1:16138155-16138155	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.579C>T; p.S193S; 1:16148622-16148622	skin	malignant_melanoma	Substitution - coding silent
c.2827G>A; p.D943N; 1:16125319-16125319	skin	malignant_melanoma	Substitution - Missense
c.2824G>A; p.D942N; 1:16129435-16129435	skin	malignant_melanoma	Substitution - Missense
c.2824G>A; p.D942N; 1:16129435-16129435	skin	malignant_melanoma	Substitution - Missense
c.942C>T; p.F314F; 1:16138312-16138312	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1819G>A; p.E607K; 1:16133526-16133526	skin	malignant_melanoma	Substitution - Missense
c.985C>T; p.P329S; 1:16138180-16138180	skin	malignant_melanoma	Substitution - Missense
c.1819G>A; p.E607K; 1:16133526-16133526	skin	malignant_melanoma	Substitution - Missense
c.1378C>T; p.P460S; 1:16135705-16135705	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.285C>T; p.F95F; 1:16148916-16148916	skin	malignant_melanoma	Substitution - coding silent
c.765_766insG; p.P256fs*27; 1:16148435-16148436	skin	malignant_melanoma	Insertion - Frameshift
c.1859G>A; p.G620E; 1:16133486-16133486	skin	malignant_melanoma	Substitution - Missense
c.418A>T; p.T140S; 1:16148783-16148783	skin	malignant_melanoma	Substitution - Missense
c.2657A>G; p.D886G; 1:16130238-16130238	skin	malignant_melanoma	Substitution - Missense
c.2061C>T; p.P687P; 1:16132432-16132432	skin	malignant_melanoma	Substitution - coding silent
c.2718C>T; p.F906F; 1:16129541-16129541	skin	malignant_melanoma	Substitution - coding silent
c.2581C>T; p.R861C; 1:16130314-16130314	skin	malignant_melanoma	Substitution - Missense
c.2116G>A; p.E706K; 1:16132273-16132273	skin	malignant_melanoma	Substitution - Missense
c.2303C>T; p.P768L; 1:16132086-16132086	skin	malignant_melanoma	Substitution - Missense
c.1054C>G; p.Q352E; 1:16138111-16138111	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2531C>T; p.S844F; 1:16130364-16130364	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2060C>T; p.P687L; 1:16132433-16132433	skin	malignant_melanoma	Substitution - Missense
c.917C>T; p.S306F; 1:16138337-16138337	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1654G>A; p.A552T; 1:16134496-16134496	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.715G>A; p.G239R; 1:16148486-16148486	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2369C>T; p.S790F; 1:16131827-16131827	skin	malignant_melanoma	Substitution - Missense
c.2369C>T; p.S790F; 1:16131827-16131827	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2369C>T; p.S790F; 1:16131827-16131827	skin	malignant_melanoma	Substitution - Missense
c.1472C>T; p.S491F; 1:16135146-16135146	skin	malignant_melanoma	Substitution - Missense
c.1488C>T; p.D496D; 1:16135130-16135130	skin	malignant_melanoma	Substitution - coding silent
c.1462G>A; p.E488K; 1:16135156-16135156	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2711T>G; p.V904G; 1:16129548-16129548	skin	malignant_melanoma	Substitution - Missense
c.754G>A; p.E252K; 1:16148447-16148447	skin	malignant_melanoma	Substitution - Missense
c.775C>T; p.Q259*; 1:16148426-16148426	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Nonsense
c.1519G>A; p.V507M; 1:16135099-16135099	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1128C>T; p.C376C; 1:16138037-16138037	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.322T>C; p.F108L; 1:16148879-16148879	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.824-1G>A; p.?; 1:16138431-16138431	stomach	carcinoma; adenocarcinoma	Unknown
c.2273T>G; p.F758C; 1:16132116-16132116	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1823T>G; p.I608S; 1:16133522-16133522	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.503G>A; p.R168H; 1:16148698-16148698	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1805T>C; p.L602S; 1:16133540-16133540	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2824G>A; p.D942N; 1:16129435-16129435	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1379delC; p.P460fs*33; 1:16135704-16135704	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1274G>A; p.R425H; 1:16137891-16137891	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2411G>A; p.G804D; 1:16131785-16131785	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1931C>T; p.A644V; 1:16133302-16133302	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1252G>A; p.V418I; 1:16137913-16137913	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2228G>A; p.R743H; 1:16132161-16132161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1090G>A; p.V364I; 1:16138075-16138075	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2041G>A; p.V681I; 1:16133192-16133192	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1682G>T; p.R561M; 1:16134468-16134468	stomach	carcinoma	Substitution - Missense
c.2277C>T; p.G759G; 1:16132112-16132112	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1457G>A; p.R486H; 1:16135161-16135161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2374C>T; p.R792W; 1:16131822-16131822	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.843T>A; p.F281L; 1:16138411-16138411	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2329G>A; p.G777S; 1:16131867-16131867	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2329G>A; p.G777S; 1:16131867-16131867	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1926G>A; p.P642P; 1:16133307-16133307	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.719delG; p.G240fs*153; 1:16148482-16148482	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2874C>T; p.I958I; 1:16125272-16125272	thyroid	other; neoplasm	Substitution - coding silent
c.2874C>T; p.I958I; 1:16125272-16125272	thyroid	other; neoplasm	Substitution - coding silent
c.1379delC; p.P460fs*33; 1:16135704-16135704	thyroid	carcinoma; anaplastic_carcinoma	Deletion - Frameshift
c.2064G>T; p.M688I; 1:16132429-16132429	thyroid	other; neoplasm	Substitution - Missense
c.1072G>T; p.E358*; 1:16138093-16138093	thyroid	other; neoplasm	Substitution - Nonsense
c.764T>G; p.V255G; 1:16148437-16148437	thyroid	other; neoplasm	Substitution - Missense
c.764T>G; p.V255G; 1:16148437-16148437	thyroid	other; neoplasm	Substitution - Missense
c.764T>G; p.V255G; 1:16148437-16148437	thyroid	other; neoplasm	Substitution - Missense
c.1983C>T; p.L661L; 1:16133250-16133250	thyroid	other; neoplasm	Substitution - coding silent
c.1393C>T; p.R465*; 1:16135690-16135690	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1738G>C; p.E580Q; 1:16133860-16133860	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1987G>A; p.E663K; 1:16133246-16133246	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1969C>T; p.R657*; 1:16133264-16133264	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.635delC; p.P212fs*181; 1:16148566-16148566	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1367G>A; p.W456*; 1:16135716-16135716	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2227C>T; p.R743C; 1:16132162-16132162	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2143C>T; p.Q715*; 1:16132246-16132246	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Nonsense
c.2450C>T; p.P817L; 1:16131746-16131746	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2143C>T; p.Q715*; 1:16132246-16132246	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.213C>T; p.N71N; 1:16148988-16148988	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1516C>T; p.Q506*; 1:16135102-16135102	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1070G>A; p.R357H; 1:16138095-16138095	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1678C>T; p.R560C; 1:16134472-16134472	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1625_1631delCTGTCGG; p.A542fs*39; 1:16134519-16134525	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1141G>A; p.A381T; 1:16138024-16138024	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1223A>G; p.Y408C; 1:16137942-16137942	urinary_tract; bladder	carcinoma	Substitution - Missense
c.205G>T; p.V69L; 1:16148996-16148996	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1918G>T; p.E640*; 1:16133315-16133315	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1938G>C; p.K646N; 1:16133295-16133295	urinary_tract; bladder	carcinoma	Substitution - Missense
c.149A>G; p.K50R; 1:16150900-16150900	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2481G>A; p.M827I; 1:16130414-16130414	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.2481G>A; p.M827I; 1:16130414-16130414	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2719C>A; p.R907S; 1:16129540-16129540	urinary_tract; bladder	carcinoma	Substitution - Missense

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COSMIC confirmed somatic mutation [Top]

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